SCAND1 and ZNF174

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		SCAND1	ZNF174
Description		SCAN domain containing 1	zinc finger protein 174
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Chromatin Fibrillar Center Nucleus Nuclear Body
	Molecular Function	Protein Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Protein Homodimerization Activity Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Positive Regulation Of DNA-templated Transcription	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription
Pathways
Drugs
Diseases
GWAS		Hip circumference adjusted for BMI ( 25673412) Refractive error ( 32231278)
Interacting Genes		45 interacting genes: AGTRAP APH1A CALCOCO2 CCDC51 DGAT2L6 GOLGA6L9 GORASP2 KRT40 LHX4 MAPK3 MAPK8 MZF1 NDUFB5 NFE2 PICK1 PNMA1 POU2AF1 RER1 RNF186 RPRM SFT2D1 SHISA5 SLC17A9 TMEM207 TMEM239 TMEM95 TRIP6 TVP23A ZKSCAN3 ZKSCAN7 ZNF165 ZNF174 ZNF202 ZNF213 ZNF24 ZNF263 ZNF446 ZNF449 ZNF496 ZSCAN12 ZSCAN16 ZSCAN20 ZSCAN21 ZSCAN25 ZSCAN32	8 interacting genes: CDK6 MZF1 SCAND1 ZKSCAN8 ZNF20 ZNF24 ZSCAN18 ZSCAN22
Entrez ID		51282	7727
HPRD ID		15298	04876
Ensembl ID		ENSG00000171222	ENSG00000103343
Uniprot IDs		P57086 Q9NZG6	I3L2H2 Q15697
PDB IDs			1Y7Q
Enriched GO Terms of Interacting Partners?		DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding Zinc Ion Binding DNA Binding Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Metal Ion Binding Regulation Of Nucleobase-containing Compound Metabolic Process Protein Binding Xenophagy Sequence-specific DNA Binding Regulation Of Gene Expression MAP Kinase Activity Regulation Of Macromolecule Biosynthetic Process	Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Zinc Ion Binding DNA Binding Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Nucleus Cyclin D2-CDK6 Complex Cyclin D3-CDK6 Complex Cyclin D1-CDK6 Complex FBXO Family Protein Binding Metal Ion Binding Gliogenesis Negative Regulation Of Monocyte Differentiation Cell Dedifferentiation Type B Pancreatic Cell Development Lateral Ventricle Development Regulation Of Hematopoietic Stem Cell Differentiation
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