CHMP1A and MITD1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CHMP1A	MITD1
Description		charged multivesicular body protein 1A	microtubule interacting and trafficking domain containing 1
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GO Annotations	Cellular Component	Autophagosome Membrane Kinetochore Condensed Nuclear Chromosome ESCRT III Complex Nucleus Nuclear Pore Cytoplasm Lysosomal Membrane Endosome Early Endosome Multivesicular Body Microtubule Organizing Center Kinetochore Microtubule Cytosol Plasma Membrane Endosome Membrane Endomembrane System Membrane Nuclear Matrix Midbody Multivesicular Body Membrane Extracellular Exosome Amphisome Membrane	Endosome Membrane Midbody Late Endosome Membrane Extracellular Exosome
	Molecular Function	Protein Binding Metallopeptidase Activity Zinc Ion Binding Protein Domain Specific Binding Identical Protein Binding Protein Homodimerization Activity	Protein Binding Protein Domain Specific Binding Phosphatidylinositol Binding Identical Protein Binding
	Biological Process	Plasma Membrane Repair Autophagy Nucleus Organization Vacuolar Transport Mitotic Chromosome Condensation Mitotic Metaphase Chromosome Alignment Negative Regulation Of Gene Expression Regulation Of Centrosome Duplication Protein Transport Vesicle-mediated Transport Nuclear Membrane Reassembly Endosome Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Late Endosome To Vacuole Transport Viral Budding From Plasma Membrane Cell Division Vesicle Fusion With Vacuole Multivesicular Body-lysosome Fusion Midbody Abscission Multivesicular Body Sorting Pathway Membrane Fission Autophagosome Maturation Regulation Of Mitotic Spindle Assembly Late Endosome To Lysosome Transport ESCRT III Complex Disassembly	Mitotic Cytokinesis Negative Regulation Of Protein Binding Viral Budding Via Host ESCRT Complex Cell Division Midbody Abscission Multivesicular Body Sorting Pathway
Pathways		HCMV Late Events
Drugs
Diseases
GWAS		Basal cell carcinoma ( 33549134) Brain morphology (MOSTest) ( 32665545) Diastolic blood pressure ( 30578418) Estimated glomerular filtration rate ( 31152163) Hemoglobin levels ( 32327693) Low tan response ( 29739929) Mean reticulocyte volume ( 32888494) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (calcium channel blockers) ( 31015401) Medication use (diuretics) ( 31015401) Plasma homocysteine levels ( 30339177) Red vs. brown/black hair color ( 30531825)	Bipolar disorder ( 21926972)
Interacting Genes		18 interacting genes: C14orf119 CHMP1B DDIT4L GORASP2 LNPK MITD1 NR1I2 PSMA1 SDCBP STAMBP TXN2 UBE2I USP8 VPS4A VPS4B VTA1 YES1 ZDHHC17	17 interacting genes: ATF7 CARD10 CEBPA CHMP1A CHMP1B CHMP2A CHMP5 DSCAM GPHN KANK2 MCPH1 NTAQ1 RTN3 TRIM14 TTC33 ZFYVE19 ZNF655
Entrez ID		5119	129531
HPRD ID		01237	14044
Ensembl ID		ENSG00000131165	ENSG00000158411
Uniprot IDs		A0A6Q8PFX8 Q9HD42	Q8WV92
PDB IDs		2JQ9 2YMB 4A5X	2YMB 4A5X 4A5Z
Enriched GO Terms of Interacting Partners?		ESCRT III Complex Disassembly ESCRT Complex Disassembly Multivesicular Body Sorting Pathway Viral Budding Via Host ESCRT Complex Midbody Abscission Nuclear Membrane Reassembly Viral Budding Mitotic Cytokinetic Process Endosome Organization Multivesicular Body Assembly Multivesicular Body Organization Late Endosome To Vacuole Transport Cytokinetic Process Endosome Transport Via Multivesicular Body Sorting Pathway Nuclear Membrane Organization Viral Budding From Plasma Membrane Membrane Assembly Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Midbody Late Endosome To Lysosome Transport Late Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Late Endosomal Microautophagy Nuclear Pore Cytoskeleton-dependent Cytokinesis Viral Release From Host Cell Plasma Membrane Repair Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Endosome Endosome Membrane Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Vesicle Organization Membrane Fission Protein-containing Complex Disassembly Viral Process Mitotic Metaphase Chromosome Alignment Late Endosome Membrane Autophagosome Maturation Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Vacuolar Transport Metaphase Chromosome Alignment Mitotic Cytokinesis Mitotic Nuclear Membrane Reassembly ATPase Complex Chromosome Localization Cell Division Extracellular Exosome Positive Regulation Of Exocytosis Nucleus Organization Proteolysis	Mitotic Cytokinetic Process Midbody Abscission ESCRT III Complex Amphisome Membrane Vesicle Fusion With Vacuole ESCRT III Complex Disassembly ESCRT Complex Disassembly Cytokinetic Process Multivesicular Body-lysosome Fusion Viral Budding From Plasma Membrane Lysosomal Membrane Organization Regulation Of Centrosome Cycle Late Endosome To Lysosome Transport Kinetochore Microtubule Viral Budding Via Host ESCRT Complex Regulation Of Mitotic Spindle Assembly Viral Budding Nuclear Membrane Reassembly Multivesicular Body Membrane Viral Release From Host Cell Plasma Membrane Repair Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Multivesicular Body Assembly Multivesicular Body Organization Regulation Of Spindle Assembly Late Endosome To Vacuole Transport Endosome Transport Via Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Organization Membrane Fission Multivesicular Body Mitotic Metaphase Chromosome Alignment Multivesicular Body Sorting Pathway Regulation Of Centrosome Duplication Nuclear Membrane Organization Autophagosome Maturation Regulation Of Cell Cycle Process Regulation Of Cell Cycle Autophagosome Membrane Metaphase Chromosome Alignment Membrane Assembly Midbody Chromosome Localization Endosome Organization Nuclear Pore Nucleus Organization Vesicle Fusion Organelle Membrane Fusion Regulation Of Microtubule-based Process Plasma Membrane Organization Lysosomal Transport
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