HSD17B11 and SFXN3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		HSD17B11	SFXN3
Description		hydroxysteroid 17-beta dehydrogenase 11	sideroflexin 3
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Lipid Droplet Cytosol	Mitochondrion Mitochondrial Inner Membrane Membrane Mitochondrial Membrane
	Molecular Function	Estradiol 17-beta-dehydrogenase [NAD(P)+] Activity Protein Binding Steroid Dehydrogenase Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor	Protein Binding Monoatomic Ion Transmembrane Transporter Activity L-serine Transmembrane Transporter Activity Transmembrane Transporter Activity
	Biological Process	Lipid Metabolic Process Steroid Biosynthetic Process Estrogen Biosynthetic Process Androgen Catabolic Process	One-carbon Metabolic Process Monoatomic Ion Transport Amino Acid Transport L-serine Transport Monoatomic Ion Transmembrane Transport Transmembrane Transport Serine Import Into Mitochondrion Mitochondrial Transmembrane Transport
Pathways		Estrogen biosynthesis
Drugs		Aetiocholanolone
Diseases
GWAS		Appendicular lean mass ( 28724990) Bulimia nervosa ( 23568457) Lean body mass ( 28724990)	Refractive error ( 32231278) Regular attendance at a pub or social club ( 29970889)
Interacting Genes		54 interacting genes: ADIPOQ AGPAT3 AGPAT4 ANKRD46 BNIP1 CMTM3 CSGALNACT2 CYBC1 DGAT2L6 DHRSX EHHADH ERG28 FAM241B GIMAP1 GOLT1A HTATIP2 LRCH4 MS4A1 NEU1 ORMDL1 OTULINL PLP2 PRAF2 PTPN9 RASGRP3 RMDN2 RTP2 SEC22A SERPINE1 SFRP4 SFT2D2 SFXN3 SLC25A46 SLC30A8 SLC67A1 STRIT1 STX7 SYS1 TMEM120B TMEM128 TMEM14B TMEM167B TMEM203 TMEM242 TMEM42 TMEM65 TMX2 TPRG1 TTPA TVP23B UBC UNC50 VEZT YIPF6	14 interacting genes: AQP6 CREB3 FCER1G HSD17B11 HSD17B13 LEPROTL1 REEP4 RETREG3 RUSF1 SCN3B TLCD4 TMEM14B TMEM51 TMX2
Entrez ID		51170	81855
HPRD ID		10881	15329
Ensembl ID		ENSG00000198189	ENSG00000107819
Uniprot IDs		Q8NBQ5	B4DRS6 Q9BWM7
PDB IDs		1YB1
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Golgi Membrane Protein Binding Endomembrane System SNAP Receptor Activity	Steroid Dehydrogenase Activity Endoplasmic Reticulum Estradiol 17-beta-dehydrogenase [NAD(P)+] Activity Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Organization Nitrate Transmembrane Transporter Activity Membrane IgE Receptor Activity Positive Regulation Of Deacetylase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?