ADIPOR1 and DPH3

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		ADIPOR1	DPH3
Description		adiponectin receptor 1	diphthamide biosynthesis 3
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GO Annotations	Cellular Component	Plasma Membrane Membrane	Nucleus Nucleoplasm Cytoplasm Cytosol Protein-containing Complex
	Molecular Function	Protein Binding Protein Kinase Binding Signaling Receptor Activity Identical Protein Binding Metal Ion Binding Adiponectin Binding Adipokinetic Hormone Receptor Activity	Protein Binding Ferrous Iron Binding Iron Chaperone Activity Metal Ion Binding
	Biological Process	Lipid Metabolic Process Fatty Acid Metabolic Process Hormone-mediated Signaling Pathway Negative Regulation Of Epithelial Cell Migration Negative Regulation Of Epithelial To Mesenchymal Transition Regulation Of Glucose Metabolic Process Regulation Of Lipid Metabolic Process Fatty Acid Oxidation Negative Regulation Of Cell Growth Leptin-mediated Signaling Pathway Adiponectin-activated Signaling Pathway Glucose Homeostasis Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Insulin Receptor Signaling Pathway Positive Regulation Of Cold-induced Thermogenesis Negative Regulation Of Non-canonical NF-kappaB Signal Transduction	TRNA Wobble Base 5-methoxycarbonylmethyl-2-thiouridinylation Protein Histidyl Modification To Diphthamide Negative Regulation Of Protein Secretion Positive Regulation Of Binding
Pathways		AMPK inhibits chREBP transcriptional activation activity	Synthesis of diphthamide-EEF2
Drugs
Diseases
GWAS		Mean platelet volume ( 27863252 32888494)
Interacting Genes		7 interacting genes: APPL1 CEP350 DPH3 NAA20 NFKBIL1 STK11 TBXA2R	6 interacting genes: ADIPOR1 MEOX2 PIH1D2 RPL8 SERGEF ZNF438
Entrez ID		51094	285381
HPRD ID		06402	16412
Ensembl ID		ENSG00000159346	ENSG00000154813
Uniprot IDs		Q96A54	Q96FX2
PDB IDs		5LXG 6KRZ 6KS0	2JR7
Enriched GO Terms of Interacting Partners?		Thromboxane Receptor Activity Thromboxane A2 Signaling Pathway Thromboxane A2 Receptor Activity Positive Regulation Of Macropinocytosis Negative Regulation Of Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis N-terminal Peptidyl-glutamine Acetylation NatB Complex N-terminal Peptidyl-aspartic Acid Acetylation N-terminal Peptidyl-glutamic Acid Acetylation Intracellular Protein-containing Complex Protein N-terminal-methionine Acetyltransferase Activity TRNA Wobble Base 5-methoxycarbonylmethyl-2-thiouridinylation Iron Chaperone Activity Protein Localization To Organelle Positive Regulation Of Vesicle Transport Along Microtubule Cellular Response To Lipopolysaccharide LRR Domain Binding Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Protein Localization To Nucleus Macropinosome Protein-N-terminal Amino-acid Acetyltransferase Activity
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