SLC35H1 and SLC10A6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC35H1	SLC10A6
Description		solute carrier family 35 member H1	solute carrier family 10 member 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cis-Golgi Network Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Plasma Membrane Membrane
	Molecular Function	Protein Binding Antiporter Activity	Protein Binding Bile Acid:sodium Symporter Activity Symporter Activity Sodium-dependent Organic Anion Transmembrane Transporter Activity
	Biological Process	Negative Regulation Of Gene Expression UDP-glucose Transmembrane Transport Fucosylation Protein O-linked Glycosylation Via Fucose Positive Regulation Of Notch Signaling Pathway	Monoatomic Ion Transport Sodium Ion Transport Lipid Transport Bile Acid And Bile Salt Transport Sodium-dependent Organic Anion Transport Transmembrane Transport
Pathways			SLC-mediated bile acid transport
Drugs
Diseases
GWAS			Eyebrow thickness ( 26926045) Insulin-related traits ( 22791750) Refractive error ( 32231278)
Interacting Genes		124 interacting genes: ACSL5 ADIPOQ AGPAT3 AGPAT4 APOD APOL2 APOL3 ARL6IP1 ARLN ASGR1 ATP13A1 BCL2L2 BET1 BMP10 BTN2A2 C14orf180 C1GALT1 C2 CCDC167 CLDN19 CMTM5 CNIH1 COL4A5 CREB3 CREB3L1 CYB561 CYB5B CYBC1 DNAJC30 EFNA5 EMC6 EMD EMP3 FA2H FAM3C FDFT1 FFAR2 FXYD3 FXYD6 FXYD6-FXYD2 GIMAP5 GOLT1A GOSR2 GPR152 IGFBP5 INSIG2 ITGAM LAT LEPROTL1 LHFPL5 LPAR3 MAL MAL2 MALL MS4A1 NINJ2 NKG7 NRM ORMDL1 ORMDL2 ORMDL3 PDCD1LG2 PEX16 PLLP PLN PLP1 PLP2 PNLIPRP1 PRB1 RTP2 RUSF1 SACM1L SCD SEC22A SEC22B SELENOK SERP1 SLC10A6 SLC12A5 SLC12A7 SLC30A3 SLC35F1 SLC38A7 SLC66A1 SMCO4 SSMEM1 STATH STRIT1 STX3 STX8 SYNDIG1 SYS1 TAP1 TECR TF THBD TMEM107 TMEM120B TMEM128 TMEM147 TMEM14A TMEM14B TMEM14C TMEM239 TMEM31 TMEM50B TMEM60 TMEM65 TMEM86A TMEM97 TPRG1 TSNARE1 TSPAN2 TSPAN33 TSPO2 TVP23B UNC93B1 UPK1B VAMP4 VEGFA VTI1B YIF1A YIPF4 YIPF6	175 interacting genes: ACSL5 AGPAT4 AIG1 ANKRD46 APOD ARL6IP1 ARLN ARV1 ATP13A1 BMP10 BTN2A2 C11orf24 C14orf180 C2CD2L C3orf52 CATSPERH CCDC167 CCL4 CDIPT CDS1 CFTR CLDND2 CMTM5 CNIH1 COL4A5 COMT COX20 CTSA CXCL16 CYB5B CYB5R3 CYP4F2 DERL1 DGAT2L6 EBP EMC6 ERG28 FA2H FAM3C FAXDC2 FIS1 FKBP8 FMO1 FUNDC2 FXYD3 FXYD6 FXYD6-FXYD2 GIMAP1 GIMAP5 GJB2 GJB6 GLB1 GOLT1B GOSR2 GPR151 GYPA GYPC HMOX1 HTATIP2 IGFBP5 ITGAM JAGN1 LPAR3 LSS MALL MFSD6 MGLL MS4A1 MS4A13 NAT8 NEU1 NINJ2 NRM OR7D4 ORMDL1 OSMR PEDS1-UBE2V1 PEX16 PIP4P1 PIP4P2 PLLP PLP1 PLP2 PNLIPRP1 PRAF2 PRRT2 PSEN1 PSENEN RNF24 RTP2 RUSF1 SACM1L SCAMP4 SCAMP5 SCD SEC22B SELENOK SERP1 SERP2 SFT2D2 SFXN1 SLC12A7 SLC25A46 SLC29A2 SLC30A2 SLC30A3 SLC35B4 SLC35G2 SLC35H1 SLC38A1 SLC38A7 SLC39A6 SLC39A9 SLC41A1 SLC61A1 SLC66A2 SLC7A1 SMAGP SMCO4 SMIM1 SNORC STATH STX12 STX3 STX7 STX8 SYNGR1 SYNJ2BP TAP1 TECR TF THBD TM4SF4 TMEM107 TMEM11 TMEM119 TMEM120B TMEM128 TMEM143 TMEM14A TMEM14B TMEM14C TMEM203 TMEM208 TMEM218 TMEM222 TMEM229B TMEM234 TMEM239 TMEM242 TMEM243 TMEM252 TMEM50B TMEM60 TMEM65 TMEM86A TMEM86B TPRG1 TRARG1 TREX1 TSNARE1 TSPAN2 TSPO2 TVP23B UBE2J1 UBIAD1 UNC50 VAMP1 VAMP3 VAMP4 YIPF1 YIPF2 YIPF6 ZDHHC15 ZFPL1
Entrez ID		51006	345274
HPRD ID		15371	11593
Ensembl ID		ENSG00000080189	ENSG00000145283
Uniprot IDs		B7Z6R4 Q9NQQ7	Q3KNW5
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum SNAP Receptor Activity Cellular Localization Structural Constituent Of Myelin Sheath Protein Binding Endomembrane System SNARE Complex Myelination Axon Ensheathment Membrane Fusion Golgi Membrane Intracellular Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intracellular Sphingolipid Homeostasis Negative Regulation Of Ceramide Biosynthetic Process Establishment Of Protein Localization Membrane Organization Organelle Fusion Golgi Vesicle Transport Negative Regulation Of Sphingolipid Biosynthetic Process Vesicle Fusion Vesicle-mediated Transport Organelle Membrane Fusion Establishment Of Localization In Cell Vesicle Fusion With Golgi Apparatus Serine Palmitoyltransferase Complex Establishment Of Protein Localization To Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Positive Regulation Of Transport Lipid Biosynthetic Process Chemical Homeostasis Exocytic Insertion Of Neurotransmitter Receptor To Postsynaptic Membrane Presynaptic Endosome Membrane Regulation Of Transport Protein Transport SNARE Binding Localization Within Membrane Regulation Of Ceramide Biosynthetic Process Regulation Of Sphingolipid Biosynthetic Process Respiratory Burst After Phagocytosis Regulation Of Membrane Lipid Metabolic Process Regulation Of Cellular Localization Membrane Docking Cholesterol Binding Vesicle Organization Lipid Metabolic Process Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Potassium:chloride Symporter Activity	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum SNAP Receptor Activity Endomembrane System Protein Binding SNARE Complex Vesicle Fusion Organelle Membrane Fusion Organelle Fusion Sterol Biosynthetic Process Lipid Metabolic Process Lipid Biosynthetic Process Membrane Fusion Establishment Of Protein Localization Membrane Organization Vesicle Docking Membrane Docking Vesicle-mediated Transport Golgi Membrane Mitochondrial Outer Membrane Plasma Membrane Organelle Localization By Membrane Tethering Golgi Apparatus Cholesterol Biosynthetic Process Transmembrane Transport Steroid Biosynthetic Process Amino Acid Transmembrane Transport Chloride Channel Inhibitor Activity Sterol Metabolic Process SNARE Binding Golgi Trans Cisterna Synaptic Vesicle Membrane Zinc Ion Transmembrane Transporter Activity Golgi Medial Cisterna Transport Vesicle Vesicle Organization Exocytic Insertion Of Neurotransmitter Receptor To Postsynaptic Membrane Phosphatidylinositol-4,5-bisphosphate 4-phosphatase Activity Alkenylglycerophosphocholine Hydrolase Activity Protein Transport Intracellular Chemical Homeostasis Structural Constituent Of Myelin Sheath Zinc Ion Transmembrane Transport Cellular Localization Zinc Ion Transport Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Intracellular Transport Chemical Homeostasis Small Molecule Biosynthetic Process
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