ATP5F1C and NGEF

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ATP5F1C	NGEF
Description		ATP synthase F1 subunit gamma	neuronal guanine nucleotide exchange factor
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Membrane Proton-transporting ATP Synthase Complex	Cytoplasm Cytosol Membrane Growth Cone Cell Projection Glutamatergic Synapse
	Molecular Function	RNA Binding Protein Binding ATP Hydrolysis Activity Proton-transporting ATP Synthase Activity, Rotational Mechanism	Guanyl-nucleotide Exchange Factor Activity Protein Binding Ephrin Receptor Binding
	Biological Process	Oxidative Phosphorylation ATP Biosynthetic Process Monoatomic Ion Transport Proton Motive Force-driven ATP Synthesis Proton Motive Force-driven Mitochondrial ATP Synthesis Proton Transmembrane Transport	Nervous System Development Cell Differentiation Regulation Of Actin Cytoskeleton Organization Regulation Of GTPase Activity Ephrin Receptor Signaling Pathway Regulation Of Small GTPase Mediated Signal Transduction Negative Regulation Of Dendritic Spine Morphogenesis Regulation Of Synapse Pruning
Pathways		Formation of ATP by chemiosmotic coupling Cristae formation Mitochondrial protein degradation	NRAGE signals death through JNK EPHA-mediated growth cone collapse EPHA-mediated growth cone collapse G alpha (12/13) signalling events RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle
Drugs		Quercetin 1-ACETYL-2-CARBOXYPIPERIDINE AUROVERTIN B Piceatannol N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE
Diseases
GWAS			Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Contrast sensitivity ( 24152035) Heel bone mineral density ( 28869591 30598549) Parkinson's disease ( 32201043) Pursuit maintenance gain ( 29064472) Schizophrenia ( 23974872 25056061 28991256 29483656 30285260) Sudden cardiac arrest ( 30169657) Superior temporal sulcus banks volume ( 31530798)
Interacting Genes		31 interacting genes: APP ATP5F1A ATP5F1B CA12 CCND3 CCT7 CDC42 CHMP2B DPP3 DUX4 EGFR ELOF1 ERCC6 FAM120A FBXO7 GATA3 GDPD2 ITIH2 MED15 MEOX2 MPP1 NDUFB3 NGEF PAWR PJA1 PNO1 POLA2 PTEN PTN SERPINA1 ZNF337	20 interacting genes: ATP5F1C C7orf25 C8orf33 EPHA4 FAM118B HCK LCOR MRPL44 NUDT21 RHOA SEPTIN2 SH2D1A SMO TAF1D TRIM55 TRIM63 TTK USP25 USP7 YIPF3
Entrez ID		509	25791
HPRD ID		00156	10442
Ensembl ID		ENSG00000165629	ENSG00000066248
Uniprot IDs		B4DL14 P36542 Q8TAS0	B4DDI2 Q8N5V2
PDB IDs		8H9E 8H9F 8H9I 8H9J 8H9L 8H9M 8H9P 8H9Q 8H9S 8H9T 8H9U 8H9V 8KHF 8KI3
Enriched GO Terms of Interacting Partners?		Regulation Of Locomotion Regulation Of Cell Migration Regulation Of Cell Motility Regulation Of Cell Cycle Angiostatin Binding Regulation Of Peptidyl-serine Phosphorylation Regulation Of Endothelial Cell Migration Regulation Of Cell Cycle Process Positive Regulation Of Cell Migration Proton-transporting Two-sector ATPase Complex Neuron Projection Organization Positive Regulation Of Cell Motility Positive Regulation Of Locomotion Regulation Of Postsynapse Organization Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Projection Organization Neuron Projection Development Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Negative Regulation Of Long-term Synaptic Potentiation Proton Motive Force-driven Mitochondrial ATP Synthesis Estrous Cycle Regulation Of G1/S Transition Of Mitotic Cell Cycle Transcription-coupled Nucleotide-excision Repair Cognition Regulation Of Mitotic Cell Cycle Proton Motive Force-driven ATP Synthesis Transmembrane Transporter Complex Negative Regulation Of Cell Population Proliferation Proton-transporting ATP Synthase Activity, Rotational Mechanism Regulation Of Cell Cycle G1/S Phase Transition Regulation Of MiRNA Transcription ATP Biosynthetic Process Protein Tyrosine Kinase Activator Activity Negative Regulation Of Cell Cycle Regulation Of MiRNA Metabolic Process Regulation Of Cell Population Proliferation Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Serine-type Endopeptidase Inhibitor Activity Regulation Of Epithelial Cell Proliferation MHC Class I Protein Binding Ovulation Cycle Dendritic Spine Morphogenesis Nervous System Development Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Response To Auditory Stimulus Proton-transporting ATP Synthase Complex Transcription Elongation Factor Complex Positive Regulation Of Peptidyl-serine Phosphorylation Nucleoside Triphosphate Biosynthetic Process Nucleobase-containing Compound Biosynthetic Process
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