GEMIN4 and STXBP2

Number of citations of the paper that reports this interaction (PubMedID 11748230)
0

Data Source:
HPRD (in vivo)

		GEMIN4	STXBP2
Description		gem nuclear organelle associated protein 4	syntaxin binding protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Cajal Body Membrane Nuclear Body Small Nuclear Ribonucleoprotein Complex SMN Complex SMN-Sm Protein Complex Extracellular Exosome Gemini Of Cajal Bodies	Extracellular Region Cytosol Plasma Membrane Apical Plasma Membrane Secretory Granule Specific Granule Azurophil Granule Zymogen Granule Membrane Cytolytic Granule Phagocytic Vesicle Extracellular Exosome Tertiary Granule Presynapse
	Molecular Function	Protein Binding Ribonucleoprotein Complex Binding	Protein Binding Syntaxin-1 Binding Syntaxin Binding Syntaxin-3 Binding
	Biological Process	Spliceosomal SnRNP Assembly RRNA Processing MRNA Processing RNA Splicing	Leukocyte Mediated Cytotoxicity Intracellular Protein Transport Exocytosis Vesicle Docking Involved In Exocytosis Protein Transport Vesicle-mediated Transport Regulation Of Mast Cell Degranulation Neutrophil Degranulation Regulated Exocytosis Cellular Response To Type II Interferon Presynaptic Dense Core Vesicle Exocytosis
Pathways		snRNP Assembly SARS-CoV-2 modulates host translation machinery	Platelet degranulation Other interleukin signaling
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)
Interacting Genes		57 interacting genes: AGO2 ALPP CALCOCO2 CCDC185 CCT3 CDC20B CERCAM CFP DDX20 DHX9 DMPK FBXL12 FLAD1 GEMIN5 GLYR1 HR KANK2 KARS1 KRTAP13-2 KRTAP13-4 KRTAP15-1 KRTAP2-3 KRTAP2-4 KRTAP9-2 LGALS1 LGALS3 LY86 MORC4 NPPB NUFIP1 PIAS3 PSMB1 PTCD1 PTEN RAD51D RN7SL1 RNASE2 RNF10 RNU1-1 RNU2-1 S1PR4 SNRPB SNRPD1 SNRPD2 SPG21 SPRY1 SQSTM1 SRRT STXBP2 STXBP3 TAP1 TOP1 UFC1 USP15 USP2 ZNF326 ZNF35	15 interacting genes: DDX20 FILNC1 GEMIN2 GEMIN4 RFX2 SMN1 SNAP23 SNRPB SNRPD2 SNRPD3 STX1A STX2 STX3 STXBP3 VAMP2
Entrez ID		50628	6813
HPRD ID		07370	03423
Ensembl ID		ENSG00000179409	ENSG00000076944
Uniprot IDs		I3L2C7 P57678 Q8WUM5 Q9HC39	Q15833 Q53GF4
PDB IDs			4CCA
Enriched GO Terms of Interacting Partners?		SMN-Sm Protein Complex Protein-RNA Complex Assembly Spliceosomal SnRNP Assembly U2 SnRNP 7-methylguanosine Cap Hypermethylation RNA Processing U4 SnRNP Methylosome Intermediate Filament Small Nuclear Ribonucleoprotein Complex RNA Splicing U1 SnRNP Tertiary Granule U5 SnRNP Presynaptic Dense Core Vesicle Exocytosis U2-type Prespliceosome Assembly U12-type Spliceosomal Complex MRNA Processing Perichromatin Fibrils U2-type Spliceosomal Complex RNA Polymerase II Complex Binding U2-type Catalytic Step 2 Spliceosome RNA Metabolic Process Positive Regulation Of Dendritic Cell Differentiation PICln-Sm Protein Complex Neuronal Dense Core Vesicle Exocytosis U1 SnRNP Binding Neutrophil Degranulation Transcription Elongation-coupled Chromatin Remodeling Keratin Filament RISC-loading Complex Dense Core Granule Exocytosis U4/U6 X U5 Tri-snRNP Complex RNA Binding Anaphase-promoting Complex Binding Calcium Ion-regulated Exocytosis Of Neurotransmitter RISC Complex Assembly MRNA Splicing, Via Spliceosome Spliceosomal Complex Assembly SiRNA Binding SMN Complex U2-type Precatalytic Spliceosome RNA Splicing, Via Transesterification Reactions Cytosol Locomotor Rhythm Ubiquitin Ligase Activator Activity Gemini Of Cajal Bodies Protein Binding Ribonucleoside Triphosphate Phosphatase Activity MRNA Metabolic Process	SMN-Sm Protein Complex Spliceosomal SnRNP Assembly SNAP Receptor Activity SMN Complex Protein-RNA Complex Assembly Gemini Of Cajal Bodies SNARE Complex Spliceosomal Complex Assembly Small Nuclear Ribonucleoprotein Complex Protein-containing Complex Assembly RNA Splicing Exocytosis Vesicle Fusion Cellular Component Assembly Organelle Membrane Fusion Protein-containing Complex Organization 7-methylguanosine Cap Hypermethylation MRNA Processing Organelle Fusion U4 SnRNP Methylosome Vesicle Organization Membrane Fusion Vesicle Docking Specific Granule SNARE Binding MRNA Metabolic Process Organelle Localization By Membrane Tethering U1 SnRNP Secretion By Cell U5 SnRNP RNA Splicing, Via Transesterification Reactions Membrane Docking Vesicle-mediated Transport In Synapse U2-type Prespliceosome Assembly U12-type Spliceosomal Complex U2 SnRNP Secretory Granule U2-type Spliceosomal Complex Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex U2-type Catalytic Step 2 Spliceosome Secretion Synaptic Vesicle Exocytosis RNA Processing Calcium-ion Regulated Exocytosis Histone Pre-mRNA DCP Binding Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Synaptobrevin 2-SNAP-25-syntaxin-1a Complex U4/U6 X U5 Tri-snRNP Complex Neuron Projection
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