OVGP1 and RASA4

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		OVGP1	RASA4
Description		oviductal glycoprotein 1	RAS p21 protein activator 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytosol Microtubule Cytoskeleton Transport Vesicle Cytoplasmic Vesicle Egg Coat Perivitelline Space	Cytoplasm Cytosol Plasma Membrane Membrane
	Molecular Function	Chitinase Activity Chitin Binding	GTPase Activator Activity Phospholipid Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Carbohydrate Metabolic Process Chitin Catabolic Process Single Fertilization Female Pregnancy Negative Regulation Of Binding Of Sperm To Zona Pellucida	Negative Regulation Of GTPase Activity Intracellular Signal Transduction Negative Regulation Of Ras Protein Signal Transduction Cellular Response To Calcium Ion Regulation Of Intracellular Signal Transduction
Pathways		Interaction With Cumulus Cells And The Zona Pellucida	Regulation of RAS by GAPs
Drugs
Diseases
GWAS		Response to antidepressants (symptom improvement) ( 29160301)	Chronotype ( 27494321) Morning vs. evening chronotype ( 27494321) Type 2 diabetes ( 32499647)
Interacting Genes		5 interacting genes: ASL DPYD MYH9 RASA4 STATH	6 interacting genes: APMAP ERBB3 HRAS JPT2 OVGP1 ZAN
Entrez ID		5016	10156
HPRD ID		04658	12135
Ensembl ID		ENSG00000085465	ENSG00000105808
Uniprot IDs		Q12889 Q86YN0	E7ERK1 O43374
PDB IDs
Enriched GO Terms of Interacting Partners?		L-arginine Biosynthetic Process Via Ornithine Argininosuccinate Lyase Activity Amino Acid Biosynthetic Process Nitrogen Utilization Ammonia Assimilation Cycle Uracil Binding Beta-alanine Metabolic Process Thymidine Catabolic Process Uracil Catabolic Process Beta-alanine Biosynthetic Process Dihydropyrimidine Dehydrogenase (NADP+) Activity Uropod Organization Cortical Granule Exocytosis Negative Regulation Of Actin Filament Severing Positive Regulation Of Protein Processing In Phagocytic Vesicle Extracellular Matrix Constituent, Lubricant Activity Pyrimidine Nucleoside Catabolic Process Thymine Metabolic Process Thymine Catabolic Process Purine Nucleobase Catabolic Process Myosin II Filament L-arginine Biosynthetic Process CMP Catabolic Process DUMP Catabolic Process Actomyosin Contractile Ring Structural Constituent Of Tooth Enamel Hydroxyapatite Binding DCMP Catabolic Process UMP Catabolic Process Cortical Granule Cytoplasmic Actin-based Contraction Involved In Cell Motility Deoxyribonucleoside Catabolic Process Saliva Secretion Amino Acid Metabolic Process Carboxylic Acid Biosynthetic Process Thymidine Metabolic Process Pyrimidine Nucleobase Catabolic Process Pyrimidine Ribonucleotide Catabolic Process Regulation Of Plasma Membrane Repair Establishment Of Meiotic Spindle Localization Establishment Of T Cell Polarity Actomyosin Supramolecular Fiber Urea Cycle Urea Metabolic Process Nitrogen Cycle Metabolic Process Pyrimidine Nucleoside Metabolic Process Nucleobase-containing Small Molecule Catabolic Process Deoxyribonucleoside Monophosphate Catabolic Process Uropod	Schwann Cell Development Positive Regulation Of Cardiac Muscle Tissue Development ERBB3:ERBB2 Complex Neuron Apoptotic Process Glial Cell Development Regulation Of Calcium-mediated Signaling Myelination Axon Ensheathment GTPase Complex Perivitelline Space ErbB-3 Class Receptor Binding Neuregulin Receptor Activity Neuregulin Binding Regulation Of Cardiac Muscle Tissue Development Negative Regulation Of Neuron Apoptotic Process Phospholipase C Activator Activity Negative Regulation Of Binding Of Sperm To Zona Pellucida Chitin Metabolic Process Regulation Of Binding Of Sperm To Zona Pellucida Chitin Catabolic Process Chitinase Activity Egg Coat Arylesterase Activity Positive Regulation Of Epithelial Cell Proliferation Schwann Cell Differentiation Oncogene-induced Cell Senescence Chitin Binding ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway Regulation Of Neuron Apoptotic Process T-helper 1 Type Immune Response Negative Regulation Of Motor Neuron Apoptotic Process Endocardial Cushion Development Regulation Of Motor Neuron Apoptotic Process Motor Neuron Apoptotic Process Apoptotic Signaling Pathway Positive Regulation Of Ruffle Assembly Endocytosis Involved In Viral Entry Into Host Cell Protein Tyrosine Kinase Activator Activity
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