NTN3 and NEO1

Number of citations of the paper that reports this interaction (PubMedID 10366627)
33

Data Source:
HPRD (in vivo)

		NTN3	NEO1
Description		netrin 3	neogenin 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Golgi Apparatus	Nucleoplasm Golgi Apparatus Plasma Membrane Cell Surface Membrane Growth Cone Intracellular Vesicle Plasma Membrane Protein Complex Postsynaptic Density Membrane Glutamatergic Synapse
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Signaling Receptor Binding Protein Binding	Protein Binding Signaling Receptor Activity Co-receptor Binding Cadherin Binding BMP Receptor Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Axonogenesis Axon Guidance	Neuron Migration Regulation Of DNA-templated Transcription Intracellular Iron Ion Homeostasis Cell Adhesion Axon Guidance Myoblast Fusion Protein Secretion Positive Regulation Of BMP Signaling Pathway Regulation Of Axon Regeneration Negative Regulation Of Axon Regeneration Negative Regulation Of Protein Secretion Multicellular Organismal-level Iron Ion Homeostasis Cell-cell Adhesion Trans-synaptic Signaling, Modulating Synaptic Transmission
Pathways		Myogenesis	Netrin-1 signaling Myogenesis
Drugs
Diseases
GWAS			Adventurousness ( 30643258) Appendicular lean mass ( 33097823) Blood protein levels ( 30072576) Brain morphology (MOSTest) ( 32665545) Dentures ( 31235808) Face memory ( 31596458) Heart rate variability traits (pvRSA/HF) ( 28613276) Heart rate variability traits (RMSSD) ( 28613276) Heart rate variability traits (SDNN) ( 28613276) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Nickel levels ( 26025379) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Red cell distribution width ( 32888494) Resting heart rate ( 27798624) Urate levels ( 31578528)
Interacting Genes		2 interacting genes: NEO1 PKD1	6 interacting genes: MTDH NTN1 NTN3 PITPNA PTK2 TTN
Entrez ID		4917	4756
HPRD ID		03827	03549
Ensembl ID		ENSG00000162068	ENSG00000067141
Uniprot IDs		O00634	Q59FP8 Q92859
PDB IDs			1X5F 1X5G 1X5H 1X5I 1X5J 1X5K 3P4L
Enriched GO Terms of Interacting Partners?		Calcium-independent Cell-matrix Adhesion Migrasome Polycystin Complex Lymph Vessel Morphogenesis Metanephric Ascending Thin Limb Development Metanephric Proximal Tubule Development Metanephric Distal Tubule Morphogenesis Distal Tubule Morphogenesis Metanephric Nephron Tubule Morphogenesis Mitocytosis Nephric Duct Development Mesonephric Duct Development Cell-cell Adhesion Proximal Tubule Development Co-receptor Binding Negative Regulation Of Axon Regeneration Plasma Membrane Protein Complex BMP Receptor Binding Cell Surface Negative Regulation Of Neuron Projection Regeneration Trans-synaptic Signaling, Modulating Synaptic Transmission Metanephric Epithelium Development Nephron Tubule Morphogenesis Nitrogen Cycle Metabolic Process Metanephric Collecting Duct Development Lung Epithelium Development Protein Heterotetramerization Metanephric Tubule Development Collecting Duct Development Golgi-associated Vesicle Membrane Metanephric Nephron Tubule Development Wnt Receptor Activity Cation Channel Complex Renal Tubule Morphogenesis Mitochondrion Distribution Intracellular Vesicle Cartilage Condensation Cell Adhesion Cell Aggregation Nephron Tubule Development Myoblast Fusion Multicellular Organismal-level Iron Ion Homeostasis Regulation Of Axon Regeneration Protein Heterooligomerization Calcium Channel Complex Embryonic Placenta Development Renal Tubule Development Regulation Of Neuron Projection Regeneration Spinal Cord Development Placenta Blood Vessel Development	Detection Of Muscle Stretch Axon Guidance Axonogenesis Neuron Projection Guidance Anatomical Structure Morphogenesis Response To Muscle Stretch Neuron Projection Morphogenesis Cell Projection Morphogenesis Detection Of Mechanical Stimulus Cell Projection Organization Neuron Projection Development Detection Of Abiotic Stimulus Titin-telethonin Complex Structural Molecule Activity Conferring Elasticity Sarcomerogenesis Protein Tyrosine Kinase Activity Quaternary Ammonium Group Binding Skeletal Muscle Myosin Thick Filament Assembly Cdc42 Protein Signal Transduction Phosphatidylglycerol Binding Myosin Filament Assembly Plasma Membrane Bounded Cell Projection Organization Phosphatidylcholine Transporter Activity Phosphatidylcholine Transfer Activity Response To Mechanical Stimulus Regulation Of Anatomical Structure Morphogenesis Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Vascular Endothelial Cell Response To Oscillatory Fluid Shear Stress Positive Regulation Of Macrophage Proliferation Telethonin Binding Skeletal Muscle Thin Filament Assembly Chemorepulsion Of Axon Anterior/posterior Axon Guidance Intercellular Canaliculus Signal Complex Assembly Mammary Gland Duct Morphogenesis Netrin-activated Signaling Pathway Detection Of Stimulus Striated Muscle Thin Filament Regulation Of Cell Junction Assembly Substrate-dependent Cell Migration, Cell Extension Phosphatidylinositol Transfer Activity JUN Kinase Binding Actin Cytoskeleton Protein Kinase A Signaling Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Motor Neuron Migration Cytoplasm Vascular Endothelial Cell Response To Fluid Shear Stress Muscle Alpha-actinin Binding
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