MT2A and EOLA1

Number of citations of the paper that reports this interaction (PubMedID 15541360)
0

Data Source:
HPRD (two hybrid, in vivo)

		MT2A	EOLA1
Description		metallothionein 2A	endothelium and lymphocyte associated ASCH domain 1
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Mitochondrion
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding
	Biological Process	Intracellular Copper Ion Homeostasis Intracellular Zinc Ion Homeostasis Detoxification Of Copper Ion Cellular Response To Interleukin-3 Cellular Response To Erythropoietin Negative Regulation Of Growth Cellular Response To Cadmium Ion Cellular Response To Copper Ion Cellular Response To Zinc Ion	Regulation Of Gene Expression Regulation Of Interleukin-6 Production
Pathways		Metallothioneins bind metals Metallothioneins bind metals Interferon gamma signaling
Drugs		Zinc Silver Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS
Interacting Genes		22 interacting genes: ADAMTS4 ARF6 ASS1 BARD1 DHODH ECT2 EOLA1 HMGB1 JMJD1C LAMTOR5 MCPH1 PAXIP1 PPDPF PRKD1 RCHY1 RIN3 SHBG SPINK7 STOM TNS2 USP25 USP40	3 interacting genes: MT2A NPC2 NUP88
Entrez ID		4502	91966
HPRD ID		08863	06625
Ensembl ID		ENSG00000125148	ENSG00000197620
Uniprot IDs		P02795	Q8TE69
PDB IDs		1MHU 2MHU	5Y7D
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Endocytosis Positive Regulation Of Mitotic Cytokinetic Process Positive Regulation Of Mitotic Cytokinesis Regulation Of Mitotic Cytokinesis Negative Regulation Of Transport Regulation Of Cellular Component Size Positive Regulation Of Protein Localization To Nucleus Liver Development Regulation Of Establishment Of Protein Localization Regulation Of Cellular Localization Cellular Response To Stress Regulation Of Nucleocytoplasmic Transport Regulation Of Protein Localization Erythrocyte Apoptotic Process Positive Regulation Of Establishment Of Protein Localization Regulation Of Endocytosis Negative Regulation Of Receptor-mediated Endocytosis Argininosuccinate Synthase Activity Argininosuccinate Metabolic Process Regulation Of Intracellular Protein Transport Regulation Of Protein Export From Nucleus Response To Ionizing Radiation Negative Regulation Of MRNA 3'-end Processing Dihydroorotate Dehydrogenase Activity Dihydroorotate Dehydrogenase (quinone) Activity Regulation Of Cytokinesis, Actomyosin Contractile Ring Assembly Positive Regulation Of Protein Import Into Nucleus Regulation Of Protein Localization To Nucleus Calcium-dependent Protein Kinase Regulator Activity Regulation Of Restriction Endodeoxyribonuclease Activity Positive Regulation Of Myeloid Progenitor Cell Differentiation Regulation Of Skeletal Muscle Contraction By Modulation Of Calcium Ion Sensitivity Of Myofibril Negative Regulation Of Mast Cell Chemotaxis	Cellular Response To Erythropoietin Cellular Response To Interleukin-3 Response To Erythropoietin Ribosomal Large Subunit Export From Nucleus Ribosomal Small Subunit Export From Nucleus Cholesterol Storage Sterol Binding Regulation Of Isoprenoid Metabolic Process Glycolipid Transport Ribosomal Subunit Export From Nucleus Detoxification Of Copper Ion Copper Ion Homeostasis Cellular Response To Cadmium Ion Cellular Response To Copper Ion Cellular Response To Zinc Ion Intracellular Copper Ion Homeostasis Structural Constituent Of Nuclear Pore Cholesterol Transfer Activity Intracellular Sterol Transport Intracellular Cholesterol Transport Intracellular Zinc Ion Homeostasis Cholesterol Efflux Response To Copper Ion Lipid Storage Intracellular Lipid Transport Response To Cadmium Ion Chemical Homeostasis Response To Zinc Ion Cholesterol Binding MRNA Export From Nucleus Cholesterol Transport Homeostatic Process RNA Export From Nucleus Intracellular Transport Nuclear Pore Phospholipid Transport Sterol Homeostasis Sterol Transport Azurophil Granule Lumen Lysosomal Lumen Carbohydrate Derivative Transport Cholesterol Homeostasis
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