RNASEK and ATP13A1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RNASEK	ATP13A1
Description		ribonuclease K	ATPase 13A1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Vacuolar Proton-transporting V-type ATPase, V0 Domain Lysosomal Membrane Plasma Membrane Endosome Membrane Endomembrane System Membrane Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle Proton-transporting V-type ATPase Complex	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Nuclease Activity Endonuclease Activity RNA Endonuclease Activity Protein Binding Hydrolase Activity	Nucleotide Binding Protein Binding ATP Binding ABC-type Manganese Transporter Activity P-type Ion Transporter Activity ATP Hydrolysis Activity ATPase-coupled Monoatomic Cation Transmembrane Transporter Activity Metal Ion Binding P-type Transmembrane Transporter Activity Membrane Protein Dislocase Activity
	Biological Process	Monoatomic Ion Transport Endocytosis Receptor-mediated Endocytosis Vacuolar Acidification Lysosomal Lumen Acidification Receptor-mediated Endocytosis Of Virus By Host Cell Endosomal Lumen Acidification Intracellular PH Reduction Golgi Lumen Acidification Proton Transmembrane Transport	Intracellular Calcium Ion Homeostasis Protein Transport Monoatomic Ion Transmembrane Transport Transmembrane Transport Manganese Ion Transmembrane Transport Monoatomic Cation Transmembrane Transport Extraction Of Mislocalized Protein From ER Membrane
Pathways			Ion transport by P-type ATPases
Drugs
Diseases
GWAS			Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Bipolar II disorder ( 31043756) Lymphocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Platelet count ( 27863252 32888494) Plateletcrit ( 27863252 32888494) Refractive error ( 32231278) Response to fenofibrate (LDL cholesterol levels) ( 27002377) Serum alkaline phosphatase levels ( 33339817) Toenail selenium levels ( 25343990) White blood cell count ( 32888494)
Interacting Genes		26 interacting genes: ARV1 ATP13A1 BNIP3 CYSLTR2 FIS1 FXYD6 GIMAP5 HMOX2 LRCH4 NINJ2 RTP2 SEC22A SERF1A SERF1B SERP2 SMAGP STX8 TAAR1 TIMM23 TMEM203 TMEM222 TMEM60 TREX1 VAPB VTI1B ZDHHC21	37 interacting genes: AGTR1 APPBP2 AQP6 ARHGEF5 BIK BUD31 CBARP CXCR2 CYB5R3 EBP ELOVL4 ERGIC3 FAM209A FFAR2 GLP1R GPR42 KMT2E MANBAL MMD RNASEK RUNX1 SCN3B SLC10A1 SLC10A6 SLC16A13 SLC30A2 SLC30A8 SLC35H1 SLC71A2 SNCA SYPL2 TLCD4 TMBIM6 TMEM14B TMEM237 UNC93A VMA21
Entrez ID		440400	57130
HPRD ID		17568	12501
Ensembl ID		ENSG00000219200	ENSG00000105726
Uniprot IDs		A0A0C4DH89 Q6P5S7	Q9HD20
PDB IDs		6WLW 6WM2 6WM3 6WM4 7U4T 7UNF
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum SNAP Receptor Activity Membrane Organization Chloride Channel Inhibitor Activity Establishment Of Protein Localization Mitochondrial Fragmentation Involved In Apoptotic Process Intracellular Calcium Ion Homeostasis Cellular Localization Organelle Localization By Membrane Tethering Protein Targeting Calcium Ion Homeostasis Membrane Docking Positive Regulation Of Mitochondrial Fission Intracellular Chemical Homeostasis Regulation Of Mitochondrial Fission Mitochondrion Autophagosome Adaptor Activity Amyloid Fibril Formation Immune Complex Formation Adenyl Deoxyribonucleotide Binding Immune Response In Brain Or Nervous System Protein Targeting To Mitochondrion Cysteinyl Leukotriene Receptor Activity Extraction Of Mislocalized Protein From ER Membrane ABC-type Manganese Transporter Activity Membrane Protein Dislocase Activity Regulation Of Plasma Membrane Sterol Distribution G Protein-coupled Amine Receptor Activity Membrane Fusion Macroautophagy	Membrane Transmembrane Transport Chemical Homeostasis Bile Acid:sodium Symporter Activity Monoatomic Ion Homeostasis Monoatomic Cation Homeostasis Zinc:proton Antiporter Activity Protein Binding Intracellular Monoatomic Cation Homeostasis Zinc Ion Import Into Organelle Intracellular Monoatomic Ion Homeostasis Plasma Membrane Homeostatic Process
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