CD200 and TMEM11

		CD200	TMEM11
Description		CD200 molecule	transmembrane protein 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Membrane Axon Neuron Projection Neuronal Cell Body Cell Body	Mitochondrion Mitochondrial Inner Membrane Plasma Membrane Membrane
	Molecular Function	Protein Binding Protein Binding Involved In Heterotypic Cell-cell Adhesion Cell-cell Adhesion Mediator Activity Glycosylated Region Protein Binding	Protein Binding
	Biological Process	Negative Regulation Of Leukocyte Activation Negative Regulation Of Cell Population Proliferation Negative Regulation Of Interleukin-6 Production Heterotypic Cell-cell Adhesion Negative Regulation Of Macrophage Activation Positive Regulation Of Macrophage Activation Negative Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Immune Response Cellular Response To Lipopolysaccharide Cellular Response To Type II Interferon Positive Regulation Of Transforming Growth Factor Beta Production Cell-cell Adhesion Regulation Of Neuroinflammatory Response Negative Regulation Of Neuroinflammatory Response Negative Regulation Of Matrix Metallopeptidase Secretion Negative Regulation Of Macrophage Migration Negative Regulation Of T Cell Migration	Mitochondrion Organization Inner Mitochondrial Membrane Organization
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Cristae formation
Drugs
Diseases
GWAS		Basal cell carcinoma ( 33549134) Blood protein levels ( 30072576) Cognitive decline rate in late mild cognitive impairment ( 26252872) Eosinophil count ( 27863252 32888494) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252 32888494) Neutrophil percentage of granulocytes ( 27863252) Sum eosinophil basophil counts ( 27863252)	Body mass index ( 26426971) Metabolite levels ( 23823483)
Interacting Genes		10 interacting genes: CASR CD200R1 CFAP91 HCRTR2 HUS1 MAST2 PLOD1 TMEM11 TMEM147 ZNF652	57 interacting genes: AQP6 ARL13B BDKRB2 BIK BNIP3 BNIP3L CCDC70 CCR4 CD200 CD79A CLDN7 CLN8 CREB3L1 CYB561 CYB5D2 DRD2 EBP ELOVL4 ERGIC3 FAM174A FAM209A FAM210B FATE1 FFAR2 GJB4 GORAB GPX8 KASH5 LEPROTL1 LMNA MRM1 MSMO1 MTIF3 MUC1 NDUFS3 OTX2 PDZK1IP1 PEX12 RETREG3 RIC3 RNASEH1 SCMH1 SGCB SLC10A6 SLC30A8 SUSD3 SUV39H1 TEX29 TMEM106C TMEM14B TMEM205 TMEM237 TMEM88 TMIE TMPRSS2 TNFSF14 YIPF6
Entrez ID		4345	8834
HPRD ID		01124	12680
Ensembl ID		ENSG00000091972	ENSG00000178307
Uniprot IDs		B4DDZ6 F8W7G1 P41217 U3KQQ2	P17152
PDB IDs
Enriched GO Terms of Interacting Partners?			Membrane Protein Binding Endoplasmic Reticulum-autophagosome Adaptor Activity
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