MEST and CRELD2

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		MEST	CRELD2
Description		mesoderm specific transcript	CRELD disulfide isomerase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Extracellular Exosome	Extracellular Space Endoplasmic Reticulum Golgi Apparatus
	Molecular Function	Catalytic Activity Protein Binding Hydrolase Activity	Protein Disulfide Isomerase Activity Calcium Ion Binding Protein Binding Isomerase Activity
	Biological Process	Mesoderm Development Regulation Of Lipid Storage Response To Retinoic Acid
Pathways
Drugs
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Acne (severe) ( 24927181)
Interacting Genes		24 interacting genes: APP BAG6 BLOC1S2 C6orf47 CD300C CEP70 CIAO2A CIDEB CMTM3 CRELD2 DBN1 FBXO7 FEZ1 FST GAD2 HGS ING5 IRF5 KIFAP3 LIME1 MPZL2 RNF19B ZNF205 ZNF579	8 interacting genes: C8orf33 CDKN2A CHRNA4 CHRNB2 HOXA1 LTB4R2 MEST SUV39H1
Entrez ID		4232	79174
HPRD ID		06776	08455
Ensembl ID		ENSG00000106484	ENSG00000184164
Uniprot IDs		A4D1L9 B4DQW6 Q5EB52	Q6UXH1
PDB IDs
Enriched GO Terms of Interacting Partners?		Gamma-tubulin Binding	Membrane Depolarization Acetylcholine Binding Behavioral Response To Nicotine Neurotransmitter Receptor Complex Acetylcholine Receptor Activity Acetylcholine-gated Monoatomic Cation-selective Channel Activity Acetylcholine-gated Channel Complex Cation Channel Complex Synaptic Transmission, Cholinergic Regulation Of Dopamine Secretion Ligand-gated Monoatomic Ion Channel Activity Neuromuscular Synaptic Transmission Extracellular Ligand-gated Monoatomic Ion Channel Activity Regulation Of Catecholamine Secretion Sensory Perception Of Pain Response To Nicotine Acetylcholine Receptor Signaling Pathway Postsynaptic Signal Transduction Response To Hypoxia Response To Decreased Oxygen Levels Cognition Excitatory Postsynaptic Potential Visual Behavior Regulation Of B Cell Proliferation Synaptic Membrane Response To Oxygen Levels Ligase Inhibitor Activity Lateral Geniculate Nucleus Development Semicircular Canal Formation Regulation Of Behavior Regulation Of Amine Transport Regulation Of Membrane Potential Regulation Of Postsynaptic Membrane Potential Abducens Nerve Formation Optokinetic Behavior Leukotriene B4 Receptor Activity Sensory Perception Positive Regulation Of Macrophage Apoptotic Process Apoptotic Process Involved In Mammary Gland Involution ENoSc Complex Leukotriene Receptor Activity Positive Regulation Of Apoptotic Process Involved In Mammary Gland Involution Regulation Of B Cell Activation Senescence-associated Heterochromatin Focus Synaptic Transmission Involved In Micturition Vestibulocochlear Nerve Development Regulation Of Circadian Sleep/wake Cycle, REM Sleep Histone H3K9 Trimethyltransferase Activity Leukotriene Signaling Pathway Negative Regulation Of Protein Neddylation
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