MAL and CD300LG

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MAL	CD300LG
Description		mal, T cell differentiation protein (MAL blood group)	CD300 molecule like family member g
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Membrane Apical Plasma Membrane Schmidt-Lanterman Incisure Plasma Membrane Raft Membrane Raft Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane	Endosome Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Multivesicular Body Membrane
	Molecular Function	Protein Binding Lipid Binding Peptidase Activator Activity Involved In Apoptotic Process Structural Constituent Of Myelin Sheath	Transmembrane Signaling Receptor Activity Protein Binding
	Biological Process	Membrane Raft Polarization Protein Localization To Paranode Region Of Axon Apoptotic Process Central Nervous System Development Central Nervous System Myelination Cell Differentiation Myelination Apical Protein Localization Protein Insertion Into Plasma Membrane Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors	Immune System Process Signal Transduction
Pathways			Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS			Apolipoprotein A1 levels ( 32203549) Eosinophil count ( 32888494) HDL cholesterol ( 28270201 30275531) HDL cholesterol levels ( 32203549) Lymphocyte count ( 32888494) Metabolic syndrome ( 31589552) Red cell distribution width ( 32888494) Triglyceride levels ( 32154731 32203549 33339817) Triglycerides ( 30275531)
Interacting Genes		81 interacting genes: AMHR2 AQP6 BCL2L13 BTN2A1 CALN1 CD300LG CD3G CD40 CD53 CD69 CLDN14 CLDN20 CLDN7 CLDN9 CLEC4C CLSTN3 CPLX4 CREB3L1 CXADR DAGLA EDA EMP1 EVI2A FAM209A FCRL2 FIBCD1 FNDC9 GJA8 GJB1 GPR152 GRAMD1A GSG1L HIBADH IL10RA IL20RB JAML KCNA1 KCNA10 KCNMB4 KLRC1 LDLRAD1 LMAN2L LMNA LRRC25 LRTM1 LSMEM1 MC4R MS4A4A MYD88 NCAPH2 NKAIN4 NPDC1 OPRM1 PERP PLA2G10 PRRT1 PTPRN RAMP1 SDC4 SGCB SHISA3 SHISA4 SLC10A1 SLC35H1 SMIM3 SPINT1 STX1A SYNDIG1 TEX29 TIGIT TM4SF18 TMEM106C TMEM174 TMEM207 TMEM213 TMEM248 TMEM30A TMEM52B TNFSF14 TSPO2 USP7	7 interacting genes: CYSRT1 KRTAP1-1 KRTAP10-3 KRTAP10-9 KRTAP5-7 MAL TMBIM6
Entrez ID		4118	146894
HPRD ID		01789	18222
Ensembl ID		ENSG00000172005	ENSG00000161649
Uniprot IDs		P21145	A0A8V8TQK5 Q6UXG3
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Plasma Membrane Protein Binding Gamma-delta T Cell Activation Anchoring Junction Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Postsynaptic Density Membrane Cell-cell Junction Organization Bicellular Tight Junction Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell Junction Organization Bicellular Tight Junction Assembly Tight Junction Assembly Tight Junction Organization Structural Molecule Activity Cell-cell Junction Assembly Leukocyte Activation	Intermediate Filament Keratin Filament Protein Insertion Into Plasma Membrane Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane Neuron Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Endoribonuclease Inhibitor Activity Membrane Raft Polarization Protein Localization To Paranode Region Of Axon Membrane Raft Distribution Peptidase Activator Activity Involved In Apoptotic Process Negative Regulation Of Calcium Ion Transport Into Cytosol Negative Regulation Of Hypoxia-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of IRE1-mediated Unfolded Protein Response Membrane Raft Localization Protein Localization To Axon Schmidt-Lanterman Incisure Structural Constituent Of Myelin Sheath Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Central Nervous System Myelination Negative Regulation Of Cellular Response To Hypoxia IRE1-mediated Unfolded Protein Response Negative Regulation Of Immunoglobulin Production
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