MAGEA11 and TRMT1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MAGEA11	TRMT1
Description		MAGE family member A11	tRNA methyltransferase 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Body	Nucleus Nucleoplasm Cytoplasm Mitochondrion
	Molecular Function	Protein Binding Histone Deacetylase Binding	TRNA Binding RNA Binding Protein Binding Methyltransferase Activity Zinc Ion Binding TRNA (guanine) Methyltransferase Activity Transferase Activity Metal Ion Binding TRNA (guanine(26)-N2)-dimethyltransferase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II	TRNA N2-guanine Methylation TRNA Modification TRNA Processing Methylation
Pathways			tRNA modification in the nucleus and cytosol
Drugs
Diseases
GWAS			Brain morphology (MOSTest) ( 32665545) Lymphocyte percentage of white cells ( 27863252) Mean platelet volume ( 32888494) Neutrophil percentage of white cells ( 27863252) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		116 interacting genes: ACMSD ACSM2B ACTN1 AKR1C3 ALDH5A1 AR ARHGAP29 BCL2L11 BEX2 BIRC2 BRD1 C18orf54 C22orf39 CASP7 CAVIN3 CCDC106 CCDC14 CCDC146 CCDC185 CCDC27 CCNA2 CDC20B CDKN2B CEP76 CLUAP1 CORO1A COX7A2L CSNK2A1 CTTNBP2 DLGAP1 DNAJC10 DOCK10 ENOX2 EWSR1 FAM156A FAM161A FBXO46 GADD45GIP1 GCSH GNPDA1 HOXB5 IFI44 IL11 IL6ST ILF3 JADE3 KIAA0408 LMBR1L LNX1 MAPK3 MCRS1 MED28 MGME1 MLF1 MTA1 MXD3 MYOZ1 NCOA2 NDEL1 NDUFAF1 NDUFB9 NIF3L1 NOL4 NOS3 NSUN4 NTAQ1 OTUB2 PCBD2 PCF11 PDE4B PHYH PIK3IP1 PIN4 PLCXD3 PNKD PNKP POLR1D PPIF PPM1K PRDX3 PRKRIP1 PSMF1 RADIL RANBP10 RBM23 REX1BD SH2D4A SNX20 SNX7 SPMIP9 STAR SUCLA2 SUOX SUV39H2 TCEA2 TCEANC TCF25 TEKTL1 THEM5 TMEM123 TPM3 TRIM27 TRIM51 TRMT1 TXN2 UBE2D4 UBE3D USP20 UTP25 VTA1 WTAP XRN2 ZBTB16 ZCCHC12 ZNF655 ZSWIM2	7 interacting genes: CFTR FBXW9 HOOK2 MAGEA11 MRI1 TERF1 TNPO2
Entrez ID		4110	55621
HPRD ID		02281	08617
Ensembl ID		ENSG00000185247	ENSG00000104907
Uniprot IDs		G5E962 P43364	Q9NXH9
PDB IDs		6WJH	9DW6
Enriched GO Terms of Interacting Partners?		Mitochondrial Matrix Protein Binding Mitochondrion Catabolic Process	Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Negative Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere Positive Regulation Of Shelterin Complex Assembly S-methyl-5-thioribose-1-phosphate Isomerase Activity Positive Regulation Of Anion Channel Activity Negative Regulation Of Telomeric D-loop Disassembly Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Positive Regulation Of Monoatomic Anion Transport Positive Regulation Of Enamel Mineralization Isomerase Activity Fibrillar Center Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Transepithelial Water Transport Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Regulation Of Establishment Of Protein Localization To Chromosome Regulation Of Establishment Of Protein Localization To Telomere Telomerase Activity Shelterin Complex Meiotic Telomere Clustering Ankyrin Repeat Binding Chromosome Localization To Nuclear Envelope Involved In Homologous Chromosome Segregation Protein Localization To Perinuclear Region Of Cytoplasm FHF Complex L-methionine Salvage L-methionine Salvage From Methylthioadenosine Amelogenesis Nuclear Telomere Cap Complex Telomere Localization Telomeric D-loop Disassembly Double-stranded Telomeric DNA Binding ATPase-coupled Inorganic Anion Transmembrane Transporter Activity G-rich Strand Telomeric DNA Binding Telomeric Loop Disassembly Microtubule Binding T-circle Formation Telomere Capping Methionine Biosynthetic Process Regulation Of Monoatomic Anion Transport Epithelial Fluid Transport Golgi-associated Vesicle Membrane HOPS Complex
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?