MAGEA8 and CCDC59

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MAGEA8	CCDC59
Description		MAGE family member A8	coiled-coil domain containing 59
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm
	Molecular Function	Protein Binding Histone Deacetylase Binding	RNA Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II
Pathways			Surfactant metabolism
Drugs
Diseases
GWAS			Hypospadias ( 25108383)
Interacting Genes		15 interacting genes: BEX5 CCDC59 GCA LMO2 LXN MAGEB4 MLH1 MTUS2 PKD2 TDRD7 UBE3A WT1 ZNF221 ZNF224 ZNF417	5 interacting genes: APP EXOSC7 HLF MAGEA8 QKI
Entrez ID		4107	29080
HPRD ID		02278	13696
Ensembl ID		ENSG00000156009	ENSG00000133773
Uniprot IDs		B2R9W4 P43361	Q9P031
PDB IDs		8FJB
Enriched GO Terms of Interacting Partners?		Metanephric S-shaped Body Morphogenesis S-shaped Body Morphogenesis Metanephric Mesenchyme Development Metanephric Epithelium Development Renal Tubule Morphogenesis Regulation Of Transcription By RNA Polymerase II Late Recombination Nodule Meiotic Metaphase I Homologous Chromosome Alignment Branching Involved In Ureteric Bud Morphogenesis Metanephric Cortical Collecting Duct Development Metanephric Cortex Development Metanephric Distal Tubule Development Mesonephric Epithelium Development Mesonephric Tubule Development Sperm Entry Positive Regulation Of Golgi Lumen Acidification Negative Regulation Of Metanephric Glomerular Mesangial Cell Proliferation Regulation Of Nucleobase-containing Compound Metabolic Process Metal Ion Binding Regulation Of Gene Expression Negative Regulation Of Nucleobase-containing Compound Metabolic Process Meiotic Spindle Midzone Assembly Meiotic Metaphase Chromosome Alignment Chiasma Polycystin Complex Metanephric Smooth Muscle Tissue Development Cellular Response To CAMP Mesenchyme Development Renal Artery Morphogenesis Kidney Epithelium Development Adrenal Cortex Formation Positive Regulation Of Metanephric Ureteric Bud Development Visceral Serous Pericardium Development Posterior Mesonephric Tubule Development Regulation Of Macromolecule Biosynthetic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Male Meiosis Chromosome Segregation MutLalpha Complex Cellular Response To Hydrostatic Pressure Detection Of Nodal Flow Regulation Of Golgi Lumen Acidification Negative Regulation Of Female Gonad Development Negative Regulation Of Glomerular Mesangial Cell Proliferation Response To CAMP Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Guanine/thymine Mispair Binding Homologous Chromosome Segregation	Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Regulation Of MiRNA Metabolic Process Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Positive Regulation Of Small Molecule Metabolic Process Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Regulation Of Nervous System Process Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Myofibroblast Contraction Internal N(7)-methylguanine-containing RNA Reader Activity Negative Regulation Of MiRNA Catabolic Process U5 SnRNA 3'-end Processing U1 SnRNA 3'-end Processing Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Negative Regulation Of Macromolecule Biosynthetic Process Cellular Response To Norepinephrine Stimulus Negative Regulation Of Biosynthetic Process Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Spliceosome-depend Formation Of Circular RNA Regulation Of Spontaneous Synaptic Transmission Regulation Of Macromolecule Biosynthetic Process NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Gene Expression Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Negative Regulation Of 3'-UTR-mediated MRNA Stabilization Exoribonuclease Complex Axon Choice Point Recognition Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) TRAMP-dependent TRNA Surveillance Pathway TRNA Surveillance
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