CENPP and AKAP19

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CENPP	AKAP19
Description		centromere protein P	A-kinase anchoring protein 19
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GO Annotations	Cellular Component	Chromosome, Centromeric Region Inner Kinetochore Nucleus Nucleoplasm Chromosome Nucleolus Cytosol	Plasma Membrane Membrane
	Molecular Function	Protein Binding	Protein Binding Protein Kinase A Regulatory Subunit Binding
	Biological Process	Chromosome Segregation CENP-A Containing Chromatin Assembly
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		End-stage renal disease ( 29885931) HDL cholesterol levels ( 32203549) Height ( 28552196 31562340) Malaria ( 31844061) Pulse pressure ( 30578418) Systolic blood pressure ( 30224653 30578418) Triglyceride levels ( 32203549) Urate levels ( 31578528) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		26 interacting genes: AKAP19 ATP6V0D2 BACH2 CCDC33 CCDC85B CEP44 GOLGA2 HAUS1 KIAA1328 KLC3 LMNA MBD3 NHLH1 NTAQ1 PKNOX2 POLR3K RNF126 RPIA SERTAD3 STXBP1 SYCE1L TEX11 TOX2 USHBP1 ZNF341 ZNF765	12 interacting genes: ARMC7 BATF2 CENPP FBXO7 MFSD6 MYOD1 NFKBIL1 PRKAR1A PRKAR2B RALGPS1 TDP2 ZMIZ2
Entrez ID		401541	84281
HPRD ID		17989	14436
Ensembl ID		ENSG00000188312	ENSG00000187699
Uniprot IDs		Q6IPU0	Q9BSF0
PDB IDs		7PB8 7PKN 7QOO 7R5S 7R5V 7XHN 7XHO 7YWX 7YYH	5HVZ
Enriched GO Terms of Interacting Partners?		Centrosome Cycle	CAMP-dependent Protein Kinase Complex CAMP-dependent Protein Kinase Regulator Activity CAMP-dependent Protein Kinase Inhibitor Activity Ubiquitin Protein Ligase Binding Protein Kinase A Catalytic Subunit Binding CAMP Binding Negative Regulation Of CAMP/PKA Signal Transduction Regulation Of CAMP/PKA Signal Transduction Ciliary Base Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite 5'-tyrosyl-DNA Phosphodiesterase Activity Tyrosyl-RNA Phosphodiesterase Activity Tyrosyl-DNA Phosphodiesterase Activity Myoblast Fate Determination Negative Regulation Of Intracellular Signal Transduction Response To Antipsychotic Drug Regulation Of Ral Protein Signal Transduction
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