ARLN and SERINC2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ARLN	SERINC2
Description		allregulin	serine incorporator 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Plasma Membrane Membrane Extracellular Exosome
	Molecular Function	Protein Binding	Acetyltransferase Activator Activity Phospholipid Scramblase Activity
	Biological Process		Phosphatidylserine Metabolic Process Plasma Membrane Phospholipid Scrambling
Pathways			Serine metabolism
Drugs
Diseases
GWAS			Alcohol dependence ( 23455491) Body mass index ( 26426971) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Heart rate response to recovery post exercise (50 sec) ( 29497042) Systolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
Interacting Genes		73 interacting genes: ADGRG3 AQP2 AQP6 ARL13B ATP2A2 BCL2L13 BIK C5AR2 CALM1 CCRL2 CD79A CISD2 CLDN9 CREB3L1 CXCR2 CYBC1 EBP ELN ELOVL4 ERGIC3 FAM174A FAM209A FFAR2 GJA5 GJB4 GJB5 GLP1R GPR61 GPX8 HHATL HTR2C JAGN1 LAPTM5 LMNA LY6G6C MILR1 MMD MMGT1 MRM3 MS4A3 NCAPH2 PLEKHO1 PLN PTGES REEP4 RETREG3 RHBDL1 RHCG SCN3B SERINC2 SHISAL1 SLC10A6 SLC14A2 SLC19A3 SLC35E3 SLC35H1 SLC39A2 SLC41A3 SLC71A2 SLCO3A1 SMO SSMEM1 STX1A SYNPR TIMMDC1 TM4SF19 TMEM101 TMEM237 TMEM248 TMEM45A TMEM45B TMEM51 YIF1A	16 interacting genes: ARLN CCDC167 GPX8 LAT MFF SEC22B SLC12A7 SLC29A2 SLC39A9 SMAGP TMEM14A TMEM167B TMEM239 TMEM42 TMEM54 TMEM86B
Entrez ID		401152	347735
HPRD ID		14223	15481
Ensembl ID		ENSG00000164096	ENSG00000168528
Uniprot IDs		Q8WVX3	Q96IM8 Q96SA4
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Transmembrane Transport Protein Binding Plasma Membrane Calcium Ion-transporting ATPase Complex Endoplasmic Reticulum Membrane G Protein-coupled Receptor Activity Connexin Complex Regulation Of Heart Rate Gap Junction Channel Activity Carbon Dioxide Transmembrane Transporter Activity One-carbon Compound Transport Carbon Dioxide Transmembrane Transport Gap Junction Regulation Of Heart Contraction Regulation Of Cardiac Muscle Cell Action Potential Transporter Inhibitor Activity SA Node Cell Action Potential Transmembrane Transporter Binding Mitochondrion-endoplasmic Reticulum Membrane Tethering Regulation Of Cardiac Muscle Cell Membrane Potential Autophagosome Membrane Docking Regulation Of Cardiac Muscle Contraction Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Regulation Of Ventricular Cardiac Muscle Cell Membrane Depolarization G Protein-coupled Receptor Signaling Pathway Renal Water Transport Regulation Of System Process Ammonium Channel Activity Regulation Of Atrial Cardiac Muscle Cell Membrane Depolarization Ammonium Transmembrane Transport Regulation Of Blood Circulation Calcium-mediated Signaling Metal Ion Transport Regulation Of Striated Muscle Contraction	Membrane
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