PRICKLE3 and SULT2B1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		PRICKLE3	SULT2B1
Description		prickle planar cell polarity protein 3	sulfotransferase family 2B member 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Plasma Membrane Membrane	Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Extracellular Exosome
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding	Nucleic Acid Binding Alcohol Sulfotransferase Activity Protein Binding Sulfotransferase Activity Cholesterol Binding Transferase Activity Small Molecule Binding Steroid Sulfotransferase Activity Cholesterol Sulfotransferase Activity Steroid Hormone Binding
	Biological Process	Cell Projection Organization	Lipid Metabolic Process Steroid Metabolic Process Cholesterol Metabolic Process Negative Regulation Of Cell Population Proliferation Positive Regulation Of Epidermal Cell Differentiation 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Sulfation
Pathways
Drugs			Adenosine 3',5'-diphosphate Pregnenolone N-cyclohexyltaurine
Diseases
GWAS		Mean platelet volume ( 32888494)	Elevated serum carcinoembryonic antigen levels ( 24941225) Non-oily fish consumption ( 32066663) Resting metabolic rate ( 28476931)
Interacting Genes		2 interacting genes: SULT2B1 TRIM29	12 interacting genes: ACYP2 DDIT4L FLACC1 KLHL8 PRICKLE3 REL SRP72 SULT1A1 SULT1B1 SULT1C3 SULT1E1 ZNF497
Entrez ID		4007	6820
HPRD ID		02120	04991
Ensembl ID		ENSG00000012211	ENSG00000088002
Uniprot IDs		B7Z5U0 B7Z8D2 H0Y413 O43900	O00204
PDB IDs			1Q1Q 1Q1Z 1Q20 1Q22
Enriched GO Terms of Interacting Partners?		Alcohol Sulfotransferase Activity Cholesterol Sulfotransferase Activity Steroid Sulfotransferase Activity Steroid Hormone Binding 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Sulfation Cadherin Binding Involved In Cell-cell Adhesion Small Molecule Binding Positive Regulation Of Epidermal Cell Differentiation Positive Regulation Of Epidermis Development Sulfotransferase Activity Cholesterol Binding Negative Regulation Of Protein Localization To Nucleus Regulation Of Epidermal Cell Differentiation Regulation Of Epidermis Development Positive Regulation Of Epithelial Cell Differentiation P53 Binding	Aryl Sulfotransferase Activity 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Sulfation Sulfotransferase Activity Ethanol Catabolic Process Ethanol Metabolic Process Flavonol 3-sulfotransferase Activity Alcohol Catabolic Process Steroid Sulfotransferase Activity Sulfur Compound Metabolic Process 3'-phosphoadenosine 5'-phosphosulfate Binding Flavonoid Metabolic Process Purine Ribonucleotide Metabolic Process Alcohol Metabolic Process Ribonucleotide Metabolic Process Ribose Phosphate Metabolic Process Xenobiotic Metabolic Process Purine Nucleotide Metabolic Process Thyroid Hormone Metabolic Process Nucleotide Metabolic Process Estrogen Metabolic Process Purine-containing Compound Metabolic Process Hormone Metabolic Process Nucleoside Phosphate Metabolic Process Steroid Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Estrogen Catabolic Process Estrone Sulfotransferase Activity Biogenic Amine Metabolic Process Acylphosphatase Activity Organic Acid Metabolic Process Amine Metabolic Process Bile-salt Sulfotransferase Activity Phosphate-containing Compound Metabolic Process Carbohydrate Derivative Metabolic Process Phenol-containing Compound Metabolic Process Alcohol Sulfotransferase Activity NF-kappaB Complex Organophosphate Metabolic Process Cytoplasm Signal Recognition Particle 7S RNA Binding Outer Dense Fiber Signal Recognition Particle Binding Signal Recognition Particle, Endoplasmic Reticulum Targeting TPR Domain Binding Regulation Of Hormone Levels Modified Amino Acid Metabolic Process Dopamine Catabolic Process Catecholamine Catabolic Process
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