AGMO and BZW2

		AGMO	BZW2
Description		alkylglycerol monooxygenase	basic leucine zipper and W2 domains 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Cytoplasm Membrane
	Molecular Function	Iron Ion Binding Protein Binding Oxidoreductase Activity Glyceryl-ether Monooxygenase Activity	Protein Binding Cadherin Binding
	Biological Process	Lipid Metabolic Process Membrane Lipid Metabolic Process Lipid Biosynthetic Process Triglyceride Biosynthetic Process Ether Lipid Metabolic Process	Regulation Of Translation Regulation Of Translational Initiation
Pathways		Triglyceride biosynthesis
Drugs
Diseases
GWAS		Adolescent idiopathic scoliosis ( 31417091) Blood sugar levels ( 29403010) Cerebrospinal P-tau181p levels ( 28247064) Fasting glucose ( 34059833) FEV1 ( 30804560) Heel bone mineral density ( 30598549) Heel bone mineral density x serum urate levels interaction ( 34046847) Lung function (FVC) ( 30061609 30804560) Obesity-related traits ( 23251661) Sweet taste preference ( 32572145) Tuberculosis ( 26767831) Type 2 diabetes ( 30054458 31049640)	Alzheimer's disease (cognitive decline) ( 23535033) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) High light scatter reticulocyte count ( 27863252 32888494) High light scatter reticulocyte percentage of red cells ( 27863252 32888494) Immature fraction of reticulocytes ( 27863252 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean platelet volume ( 27863252 32888494) Metabolite levels ( 23823483) Neurofibrillary tangles ( 31497858) Red cell distribution width ( 32888494) Reticulocyte count ( 27863252 32888494) Reticulocyte fraction of red cells ( 27863252 32888494) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
Interacting Genes		2 interacting genes: AQP6 BZW2	10 interacting genes: AGMO AGR3 CDC42 CEBPA EIF2A EIF2B1 EIF3A GSK3B LINC01554 OGT
Entrez ID		392636	28969
HPRD ID		13362	16571
Ensembl ID		ENSG00000187546	ENSG00000136261
Uniprot IDs		Q6ZNB7 X5D773	B5MCE7 Q9Y6E2
PDB IDs
Enriched GO Terms of Interacting Partners?		PH-gated Chloride Channel Activity Nitrate Transmembrane Transporter Activity Nitrate Transmembrane Transport Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Monoatomic Anion Channel Activity Ammonium Transmembrane Transport Ammonium Channel Activity Renal Water Transport Water Channel Activity Carbon Dioxide Transport One-carbon Compound Transport Water Transport Fluid Transport Channel Activity Chloride Transmembrane Transport Odontogenesis Chloride Transport Regulation Of Translational Initiation Inorganic Anion Transmembrane Transport Renal System Process Monoatomic Anion Transmembrane Transport Inorganic Anion Transport Monoatomic Anion Transport Cytoplasmic Vesicle Membrane	Translational Initiation Cytoplasmic Translational Initiation Translation Initiation Factor Activity Translation Negative Regulation Of Protein-containing Complex Assembly Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process ER-nucleus Signaling Pathway Macrophage Differentiation Neuron Projection Organization Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Regulation Of Microtubule Anchoring At Centrosome Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Membraneless Organelle Assembly Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Glyceryl-ether Monooxygenase Activity Protein-containing Complex GBD Domain Binding Storage Vacuole Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Chromatin DNA Binding Regulation Of Protein Catabolic Process Macromolecule Biosynthetic Process Regulation Of Proteolysis Response To Vitamin B2 C/EBP Complex Superior Temporal Gyrus Development TOR Signaling Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Negative Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Mesenchymal Stem Cell Differentiation Negative Regulation Of Glycogen (starch) Synthase Activity Eukaryotic Translation Initiation Factor 3 Complex, EIF3e Establishment Of Cell Polarity Endothelin Receptor Signaling Pathway Involved In Heart Process Cellular Response To Cytokine Stimulus Regulation Of Protein-containing Complex Assembly CHOP-C/EBP Complex Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Translation Protein O-acetylglucosaminyltransferase Activity Translation Reinitiation Multi-eIF Complex Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Apolipoprotein A-I Receptor Binding
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