SUMO1P1 and HNRNPC

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		SUMO1P1	HNRNPC
Description		SUMO1 pseudogene 1	heterogeneous nuclear ribonucleoprotein C
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus PML Body	Chromatin Extracellular Region Nucleus Nucleoplasm Spliceosomal Complex Telomerase Holoenzyme Complex Cytosol Actin Cytoskeleton Membrane Protein-containing Complex Extracellular Exosome Catalytic Step 2 Spliceosome Ribonucleoprotein Complex
	Molecular Function	Protein Binding Transcription Factor Binding Protein Tag Activity Identical Protein Binding Ubiquitin-like Protein Ligase Binding	Nucleic Acid Binding RNA Binding MRNA 3'-UTR Binding Protein Binding Poly(U) RNA Binding Nucleosomal DNA Binding Identical Protein Binding Telomerase RNA Binding N6-methyladenosine-containing RNA Reader Activity
	Biological Process	Protein Sumoylation PML Body Organization	MRNA Splicing, Via Spliceosome Osteoblast Differentiation Chromatin Remodeling MRNA Processing RNA Splicing Negative Regulation Of Telomere Maintenance Via Telomerase 3'-UTR-mediated MRNA Stabilization
Pathways			SUMOylation of RNA binding proteins mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA RHOBTB2 GTPase cycle RHOBTB1 GTPase cycle
Drugs
Diseases
GWAS		Copper levels ( 26025379) Cortical volume ( 32963231) Polycystic ovary syndrome ( 22885925)	Bipolar disorder ( 21738484 31043756) Height ( 31562340)
Interacting Genes		33 interacting genes: ACTN3 ARK2N AXIN1 CKS1B EDARADD ESRRG FAM118B FAM200A FHL2 FKBP6 GMCL1 HNRNPC KRTAP9-2 L3MBTL3 LCE2A LCE2D MAPK1IP1L NAB2 PHC1 PIAS1 PIAS2 SATB1 SETBP1 SOX5 STX1A SUMO1 TRAF2 TRIM23 UBA2 UBE2I ZBTB26 ZBTB6 ZNRD2	59 interacting genes: AP1M1 BARD1 BRCA1 BRCA2 BRIP1 CCDC85B CDKN2A CSNK1A1 CSNK2A1 CSNK2A2 DHX9 DISC1 DLG4 EPS8 ERG ESR1 FAS FXR2 GRB2 IL7R KHDRBS3 KPNA2 KPNA3 KPNA4 KPNA5 KRAS LMO2 LMO3 MAPT MEOX2 NUFIP2 OGT PALB2 PAX6 PDGFB PHKB PIN1 PJA1 PRKDC PTBP2 RAD51 RALYL RBM41 RBPMS2 SDCBP SF3B2 SMARCD1 SREK1 SRPK2 SUMO1 SUMO1P1 TRAF3 UBE2I USP7 WEE2-AS1 YWHAE YWHAQ ZFYVE26 ZNF581
Entrez ID		391257	3183
HPRD ID			01243
Ensembl ID			ENSG00000092199
Uniprot IDs			P07910
PDB IDs			1TXP 1WF2 2MXY 2MZ1 3LN4
Enriched GO Terms of Interacting Partners?		Protein Sumoylation Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Identical Protein Binding Small Protein Activating Enzyme Binding Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process PML Body Negative Regulation Of Metabolic Process Protein Modification By Small Protein Conjugation Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process Transcription Factor Binding SUMO Transferase Activity Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Post-translational Protein Modification Presynaptic Cytosol Postsynaptic Cytosol Transcription Corepressor Activity Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Primary Metabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Metabolic Process Regulation Of Gene Expression Ubiquitin Protein Ligase Binding SUMO Ligase Activity Positive Regulation Of Protein Sumoylation Negative Regulation Of Calcineurin-NFAT Signaling Cascade Protein Binding Nucleoplasm Regulation Of Macromolecule Biosynthetic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Nucleus Positive Regulation Of Catabolic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of Proteolysis Nuclear Body Negative Regulation Of Calcium-mediated Signaling Chromatin Organization Regulation Of Protein Sumoylation Enzyme Binding Synaptonemal Complex Positive Regulation Of Proteasomal Protein Catabolic Process Chromatin Remodeling Positive Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate	Nuclear Ubiquitin Ligase Complex Nucleus Macromolecule Metabolic Process RNA Binding Nucleic Acid Metabolic Process Protein Localization To Organelle Regulation Of Nucleobase-containing Compound Metabolic Process Nucleoplasm Regulation Of Primary Metabolic Process Regulation Of Intracellular Signal Transduction Positive Regulation Of Metabolic Process Regulation Of Signal Transduction Regulation Of RNA Metabolic Process NLS-dependent Protein Nuclear Import Complex Intracellular Signal Transduction Regulation Of Metabolic Process Regulation Of Macromolecule Metabolic Process Double-strand Break Repair Regulation Of Cell Communication Regulation Of Signaling BRCA1-B Complex DNA Metabolic Process DNA Repair DNA Recombination Regulation Of Ubiquitin-dependent Protein Catabolic Process Identical Protein Binding Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process DNA Damage Response Regulation Of Cell Cycle Nuclear Body Organization Double-strand Break Repair Via Homologous Recombination Regulation Of Macromolecule Biosynthetic Process Recombinational Repair Nuclear Import Signal Receptor Activity Cytosol Regulation Of DNA Metabolic Process Nuclear Localization Sequence Binding Regulation Of Cell Cycle Process Regulation Of DNA Damage Checkpoint Regulation Of DNA-templated Transcription Response To Stress Regulation Of RNA Biosynthetic Process NLS-bearing Protein Import Into Nucleus Regulation Of Cellular Response To Stress Cellular Component Assembly PML Body Cytoplasm Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Protein Localization To Nucleus
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