CFAP77 and PRRC2B

		CFAP77	PRRC2B
Description		cilia and flagella associated protein 77	proline rich coiled-coil 2B
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Axonemal Microtubule Cilium Axoneme Motile Cilium Sperm Flagellum Cell Projection Axonemal B Tubule Inner Sheath
	Molecular Function	Protein Binding	RNA Binding Protein Binding
	Biological Process	Flagellated Sperm Motility	Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Irritable mood ( 29500382) Triglyceride levels in HIV infection ( 33109212) Type 2 diabetes ( 30054458)	Femur bone mineral density x serum urate levels interaction ( 34046847) Lung function ( 31902109) Urate levels ( 31578528)
Interacting Genes		2 interacting genes: PRRC2B TCF4	48 interacting genes: AK8 ALG13 ANKHD1 APP ATN1 ATXN1 ATXN1L BAG4 BCAS2 CFAP77 CRK CTBP1 DAPK1 DDX11 DDX31 DIMT1 DMRTB1 DNAJC5 DPY30 EHMT2 ESS2 EXOSC1 EXOSC4 EXOSC7 FBXO7 GTF3C4 IPO5 LSM5 MRPL44 NIP7 NXF1 NXF5 PLPP7 PRPF39 QKI RBFOX2 RBPMS RERE RPL13 SETX SF1 SRPK2 SRSF4 TRNAU1AP TXNL4A UCK1 YTHDF1 YTHDF3
Entrez ID		389799	84726
HPRD ID		13522	13805
Ensembl ID		ENSG00000188523	ENSG00000288701
Uniprot IDs		A2A393 Q6ZQR2	Q5JSZ5 Q9BU62
PDB IDs		7UNG 8J07
Enriched GO Terms of Interacting Partners?		TFIIB-class Transcription Factor Binding Beta-catenin-TCF7L2 Complex Beta-catenin-TCF Complex	RNA Binding Nucleus RNA Processing RNA Metabolic Process Nucleic Acid Binding RNA Splicing MRNA Metabolic Process Nucleolus MRNA Processing MRNA Binding Nucleoplasm Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Splicing, Via Transesterification Reactions Nucleolar Exosome (RNase Complex) Regulation Of MRNA Metabolic Process Cytoplasmic Stress Granule Cytoplasmic Exosome (RNase Complex) RNA Exonuclease Activity Macromolecule Metabolic Process Regulation Of RNA Splicing Nuclear Exosome (RNase Complex) Exosome (RNase Complex) Regulation Of MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing POZ Domain Binding Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Stress Granule Assembly Negative Regulation Of Macromolecule Metabolic Process MRNA Splice Site Recognition Exoribonuclease Complex Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Spliceosomal Complex Nuclear RNA Export Factor Complex U4 SnRNA 3'-end Processing Protein-RNA Complex Assembly Cytoplasm Transcription Corepressor Activity Negative Regulation Of Metabolic Process Spliceosomal Complex Assembly Memory Negative Regulation Of RNA Metabolic Process Regulation Of Macromolecule Metabolic Process Nuclear MRNA Surveillance Nuclear Inclusion Body N6-methyladenosine-containing RNA Reader Activity
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