TMIGD1 and EFCAB5

		TMIGD1	EFCAB5
Description		transmembrane and immunoglobulin domain containing 1	EF-hand calcium binding domain 5
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytosol Plasma Membrane Cell Surface Membrane Neuron Projection
	Molecular Function	Protein Binding Protein Homodimerization Activity Cell Adhesion Mediator Activity Cell-cell Adhesion Mediator Activity	Calcium Ion Binding Metal Ion Binding
	Biological Process	Response To Nutrient Intracellular Protein Localization Cell Migration Regulation Of Cell Migration Regulation Of Cell Population Proliferation Negative Regulation Of Apoptotic Process Cell-cell Junction Organization Negative Regulation Of Epithelial Cell Proliferation Intestinal Epithelial Cell Maturation Cellular Response To Hydroperoxide Regulation Of Membrane Permeability Cell-cell Adhesion Cell Aggregation Brush Border Assembly
Pathways
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Appendicular lean mass ( 33097823)	Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease ( 30804561 33909500) Coffee consumption (cups per day) ( 25288136) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Hemoglobin levels ( 32327693) Lung function (FEV1/FVC) ( 28166213) PR interval ( 32439900) QRS complex (12-leadsum) ( 27659466)
Interacting Genes		2 interacting genes: EFCAB5 MYO18A	3 interacting genes: LYRM9 TMIGD1 USP7
Entrez ID		388364	374786
HPRD ID		18274	13528
Ensembl ID		ENSG00000182271	ENSG00000176927
Uniprot IDs		Q6UXZ0	A4FU69
PDB IDs		8CD3
Enriched GO Terms of Interacting Partners?		Actomyosin Asymmetric Golgi Ribbon Formation Regulation Of Opsonization Golgi Vesicle Budding Golgi Ribbon Formation Positive Regulation Of Opsonization Myosin Filament Myosin II Complex Vesicle Budding From Membrane ATP-dependent Activity, Acting On DNA ADP Binding Myosin Complex	Regulation Of Establishment Of Protein Localization To Chromosome Monoubiquitinated Protein Deubiquitination Regulation Of Establishment Of Protein Localization To Telomere DNA Alkylation Repair Symbiont-mediated Disruption Of Host Cell PML Body Regulation Of Retrograde Transport, Endosome To Golgi Transcription-coupled Nucleotide-excision Repair Brush Border Assembly Cell Adhesion Mediator Activity Columnar/cuboidal Epithelial Cell Maturation Cellular Response To Hydroperoxide Intestinal Epithelial Cell Maturation Response To Nutrient Levels Regulation Of Telomere Capping Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation Negative Regulation Of Gluconeogenesis K48-linked Deubiquitinase Activity Response To Hydroperoxide Cell Aggregation Deubiquitinase Activity Epithelial Cell Maturation
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