KRTAP5-3 and FUCA2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRTAP5-3	FUCA2
Description		keratin associated protein 5-3	alpha-L-fucosidase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament	Extracellular Region Extracellular Space Lysosome Endoplasmic Reticulum Lumen Azurophil Granule Lumen Extracellular Exosome
	Molecular Function	Protein Binding	Alpha-L-fucosidase Activity Protein Binding Hydrolase Activity Hydrolase Activity, Acting On Glycosyl Bonds
	Biological Process		Carbohydrate Metabolic Process Fucose Metabolic Process Response To Bacterium Glycoside Catabolic Process Regulation Of Entry Of Bacterium Into Host Cell
Pathways		Keratinization	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Neutrophil degranulation Post-translational protein phosphorylation
Drugs		Beta-D-Glucose
Diseases
GWAS			Multiple sclerosis ( 31604244)
Interacting Genes		64 interacting genes: ADAMTSL4 CATSPER1 CRCT1 CREB5 CRY2 CYSRT1 ECM1 FBXO34 FUCA2 GLRX3 HOXA1 KPRP KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP15-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-1 KRTAP5-2 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LELP1 MEOX2 NBPF19 NOTCH2NLA NR4A3 NUFIP2 OTX1 POU4F2 RAMP3 RGS17 RGS20 SMCP	19 interacting genes: GPR37 GPRC5B GUCD1 HOXA1 KRTAP10-1 KRTAP4-12 KRTAP5-2 KRTAP5-3 LCE1A LCE1B LCE1E LCE4A MEOX2 NUFIP2 OGT PIN1 TNPO2 VWC2 WNT11
Entrez ID		387266	2519
HPRD ID		12395	00649
Ensembl ID		ENSG00000196224	ENSG00000001036
Uniprot IDs		Q6L8H2	Q9BTY2
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Keratinization Epidermis Development Tissue Development Hair Cycle Identical Protein Binding Protein Binding	Keratinization Epidermis Development Intermediate Filament Tissue Development Somite Development
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