KRT13 and KRT78

Number of citations of the paper that reports this interaction (PubMedID 40437099)
172

Data Source:
BioGRID (two hybrid, biochemical)

		KRT13	KRT78
Description		keratin 13	keratin 78
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Cytoskeleton Intermediate Filament Keratin Filament Intermediate Filament Cytoskeleton Extracellular Exosome	Extracellular Space Cytosol Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis	Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Morphogenesis Of An Epithelium Cytoskeleton Organization Epithelial Cell Differentiation Regulation Of Translation In Response To Stress Intermediate Filament Organization	Keratinization Intermediate Filament Organization
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
Drugs
Diseases		White sponge nevus
GWAS			Aspartate aminotransferase levels ( 33547301) Gamma glutamyl transferase levels ( 29403010)
Interacting Genes		71 interacting genes: ABI2 ABI3 AIRIM AMOTL2 ANKRD36BP1 APC ATP5PO BLOC1S6 C1orf216 CATSPERT CCHCR1 CCNC CEP57 CEP57L1 CFTR DES DNAAF4 EIF4E2 EXOSC5 FANCG FARS2 FBF1 GFAP GLYCTK GOLGA8EP GRAP2 HGS HOOK3 IFT20 KLC3 KLC4 KRT1 KRT2 KRT20 KRT3 KRT5 KRT6A KRT6B KRT6C KRT7 KRT71 KRT72 KRT74 KRT75 KRT76 KRT78 KRT79 KRT8 KRT81 KRT85 LSM2 MOS MYH1 MYO15B NEFL NEIL3 ORMDL3 PPP1R18 PSMA1 PSMB1 PSMB2 RTL8B SGF29 SPG21 TLE5 TMSB4X TRIM42 TSG101 TXLNA TXLNB ZNF688	24 interacting genes: C14orf119 KRT13 KRT14 KRT15 KRT16 KRT19 KRT24 KRT25 KRT26 KRT27 KRT31 KRT32 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT39 KRT40 KRT72 SRPK2 TRIM54 UCHL5
Entrez ID		3860	196374
HPRD ID		01016	17171
Ensembl ID		ENSG00000171401	ENSG00000170423
Uniprot IDs		A1A4E9 P13646	Q8N1N4
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Constituent Of Skin Epidermis Keratin Filament Intermediate Filament Keratinization Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Intermediate Filament Cytoskeleton Cytosol Structural Constituent Of Cytoskeleton Intermediate Filament Polymerization Or Depolymerization Extracellular Exosome Cytoskeleton Cytoplasm Protein Binding Proteasome Core Complex Epidermis Development Actin-based Cell Projection	Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Structural Molecule Activity Morphogenesis Of An Epithelium Supramolecular Fiber Organization Epithelial Cell Differentiation Tissue Morphogenesis Cytoskeleton Organization Cytoskeleton Anatomical Structure Morphogenesis Organelle Organization Cell Differentiation Cellular Developmental Process Extracellular Exosome Cytosol Developmental Process Hair Cycle Epidermis Development Structural Constituent Of Cytoskeleton Tissue Development Hair Follicle Morphogenesis Intermediate Filament Cytoskeleton Cornified Envelope Protein Binding Keratinocyte Differentiation Keratinization Terminal Web Hair Cycle Process Nuclear Speck Organization
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