KRT3 and SAPCD2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRT3	SAPCD2
Description		keratin 3	suppressor APC domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament Extracellular Exosome	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Plasma Membrane Bicellular Tight Junction Cell Cortex Membrane Apical Plasma Membrane Apical Junction Complex Apical Cortex Anchoring Junction
	Molecular Function	Protein Binding Structural Constituent Of Skin Epidermis	Protein Binding
	Biological Process	Epithelial Cell Differentiation Keratinization Intermediate Filament Cytoskeleton Organization Intermediate Filament Organization	Establishment Of Mitotic Spindle Orientation Positive Regulation Of Cell Population Proliferation Cell Division Regulation Of Establishment Of Planar Polarity Symmetric Cell Division Negative Regulation Of Protein Localization To Cell Cortex
Pathways		Keratinization Formation of the cornified envelope
Drugs
Diseases		Meesmann corneal dystrophy
GWAS			Aspartate aminotransferase levels ( 33547301) Platelet count ( 32888494)
Interacting Genes		42 interacting genes: BPIFA1 C3orf62 CCDC197 DEUP1 HAUS1 HGS HYI KIFC3 KRT13 KRT14 KRT15 KRT20 KRT24 KRT25 KRT26 KRT27 KRT28 KRT31 KRT32 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT39 KRT40 KRT6A KRTAP13-2 LHX3 LURAP1 NUP62 OIP5 PLEKHG4 SAPCD2 SPAG5 TRAF1 TRIM27 TRIM54 WASHC1 WWOX ZNF426	13 interacting genes: AIRIM ATF4 BFSP2 CYSRT1 EXOC7 GMNN GPRASP2 KRT3 KRTAP1-3 MDFI RALBP1 USHBP1 VCL
Entrez ID		3850	89958
HPRD ID		01013	12943
Ensembl ID		ENSG00000186442	ENSG00000186193
Uniprot IDs		P12035	Q86UD0
PDB IDs
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Keratin Filament Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Structural Molecule Activity Morphogenesis Of An Epithelium Epithelial Cell Differentiation Supramolecular Fiber Organization Tissue Morphogenesis Cytoskeleton Organization Cytoskeleton Anatomical Structure Morphogenesis Organelle Organization Cell Differentiation Cellular Developmental Process Cytosol Extracellular Exosome Structural Constituent Of Cytoskeleton Hair Cycle Developmental Process Epidermis Development Protein Binding Hair Follicle Morphogenesis Phosphatidylinositol 3-kinase Inhibitor Activity Intermediate Filament Cytoskeleton Regulation Of Microtubule Cytoskeleton Organization Arp2/3 Complex-mediated Actin Nucleation Hair Cycle Process Microtubule Organizing Center Organization Regulation Of Cytoskeleton Organization Actin Nucleation Centriole Assembly Hydroxypyruvate Isomerase Activity Symmetric Cell Division Negative Regulation Of Protein Localization To Cell Cortex
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