KRAS and CALM1

Number of citations of the paper that reports this interaction (PubMedID 11585916)
61

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		KRAS	CALM1
Description		KRAS proto-oncogene, GTPase	calmodulin 1
Image
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Mitochondrial Outer Membrane Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Focal Adhesion Cytoplasmic Side Of Plasma Membrane Endomembrane System Membrane	Spindle Pole Extracellular Region Nucleus Nucleoplasm Cytoplasm Centrosome Spindle Cytosol Cytoskeleton Spindle Microtubule Plasma Membrane Cilium Voltage-gated Potassium Channel Complex Membrane Sarcomere Synaptic Vesicle Membrane Motile Cilium Vesicle Protein-containing Complex Calcium Channel Complex Cell Projection Myelin Sheath Calyx Of Held Sperm Midpiece Presynaptic Cytosol Catalytic Complex
	Molecular Function	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity GMP Binding GDP Binding LRR Domain Binding Identical Protein Binding Protein-membrane Adaptor Activity Protein-containing Complex Binding	Calcium Channel Regulator Activity Calcium Ion Binding Protein Binding Adenylate Cyclase Activator Activity Calcium Channel Inhibitor Activity Protein Kinase Binding Titin Binding Protein Serine/threonine Kinase Activator Activity Transmembrane Transporter Binding Metal Ion Binding Calcium-dependent Protein Binding Protein Phosphatase Activator Activity Transporter Inhibitor Activity
	Biological Process	MAPK Cascade Liver Development Signal Transduction Ras Protein Signal Transduction Female Pregnancy Cell Population Proliferation Visual Learning Response To Gravity Gene Expression Positive Regulation Of Gene Expression Glial Cell Proliferation Rac Protein Signal Transduction Cytokine-mediated Signaling Pathway Forebrain Astrocyte Development Actin Cytoskeleton Organization Negative Regulation Of Epithelial Cell Differentiation Regulation Of Synaptic Transmission, GABAergic Positive Regulation Of Rac Protein Signal Transduction Response To Isolation Stress Skeletal Muscle Cell Differentiation Negative Regulation Of Neuron Apoptotic Process Regulation Of Long-term Neuronal Synaptic Plasticity Homeostasis Of Number Of Cells Within A Tissue Striated Muscle Cell Differentiation Response To Glucocorticoid Response To Mineralocorticoid Neuron Apoptotic Process Myoblast Proliferation Cardiac Muscle Cell Proliferation Positive Regulation Of Glial Cell Proliferation Epithelial Tube Branching Involved In Lung Morphogenesis Type I Pneumocyte Differentiation Positive Regulation Of Cellular Senescence	G2/M Transition Of Mitotic Cell Cycle Regulation Of Heart Rate Detection Of Calcium Ion G Protein-coupled Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway Via JAK-STAT Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Autophagosome Membrane Docking Substantia Nigra Development Regulation Of Cytokinesis Cellular Response To Interferon-beta Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Regulation Of Calcium-mediated Signaling Response To Calcium Ion Regulation Of Cardiac Muscle Contraction Long-term Synaptic Potentiation Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Cellular Response To Type II Interferon Calcineurin-mediated Signaling Regulation Of Cardiac Muscle Cell Action Potential Organelle Localization By Membrane Tethering Presynaptic Endocytosis Negative Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Negative Regulation Of Calcium Ion Export Across Plasma Membrane Mitochondrion-endoplasmic Reticulum Membrane Tethering
Pathways		Signaling by moderate kinase activity BRAF mutants Paradoxical activation of RAF signaling by kinase inactive BRAF RUNX3 regulates p14-ARF RAS processing Signaling downstream of RAS mutants Signaling by CSF3 (G-CSF) Signaling by CSF1 (M-CSF) in myeloid cells Signaling by RAS GAP mutants Signaling by RAS GTPase mutants	CaMK IV-mediated phosphorylation of CREB CaMK IV-mediated phosphorylation of CREB Calmodulin induced events Cam-PDE 1 activation CaM pathway Platelet degranulation Translocation of SLC2A4 (GLUT4) to the plasma membrane Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation PKA activation DARPP-32 events Synthesis of IP3 and IP4 in the cytosol Calcineurin activates NFAT Calcineurin activates NFAT eNOS activation Transcriptional activation of mitochondrial biogenesis Inactivation, recovery and regulation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade Stimuli-sensing channels FCERI mediated Ca+2 mobilization FCERI mediated Ca+2 mobilization Ca2+ pathway Reduction of cytosolic Ca++ levels Sodium/Calcium exchangers Unblocking of NMDA receptors, glutamate binding and activation CREB1 phosphorylation through the activation of Adenylate Cyclase CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde Ras activation upon Ca2+ influx through NMDA receptor Smooth Muscle Contraction Smooth Muscle Contraction Activation of Ca-permeable Kainate Receptor Uptake and function of anthrax toxins VEGFR2 mediated vascular permeability VEGFR2 mediated cell proliferation Phase 0 - rapid depolarisation Ion homeostasis CLEC7A (Dectin-1) induces NFAT activation CLEC7A (Dectin-1) induces NFAT activation RHO GTPases activate IQGAPs RHO GTPases activate PAKs RHO GTPases activate PAKs RAF activation RAF/MAP kinase cascade Signaling by moderate kinase activity BRAF mutants Signaling by BRAF and RAF1 fusions Paradoxical activation of RAF signaling by kinase inactive BRAF Glycogen breakdown (glycogenolysis) Glycogen breakdown (glycogenolysis) Protein methylation Extra-nuclear estrogen signaling Loss of phosphorylation of MECP2 at T308 Regulation of MECP2 expression and activity Ion transport by P-type ATPases Negative regulation of NMDA receptor-mediated neuronal transmission Activation of RAC1 downstream of NMDARs Activation of RAC1 downstream of NMDARs Activation of AMPK downstream of NMDARs Long-term potentiation Long-term potentiation RAS processing Signaling downstream of RAS mutants Signaling by RAF1 mutants FCGR3A-mediated IL10 synthesis FCGR3A-mediated IL10 synthesis Antigen activates B Cell Receptor (BCR) leading to generation of second messengers High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells CASP4 inflammasome assembly Microbial factors inhibit CASP4 activity CASP4 inflammasome assembly Microbial factors inhibit CASP4 activity CASP4 inflammasome assembly Microbial factors inhibit CASP4 activity
Drugs		[(3,7,11-TRIMETHYL-DODECA-2,6,10-TRIENYLOXYCARBAMOYL)-METHYL]-PHOSPHONIC ACID Farnesyl diphosphate Adagrasib Sotorasib	Chlorpromazine Cinchocaine Nicardipine Fluphenazine Isoflurane Trifluoperazine Loperamide Perphenazine Phenoxybenzamine Felodipine Melatonin Promethazine Pimozide Nifedipine Bepridil Calcium Aprindine Deacetoxyvinzolidine tert-butanol Trimethyllysine Dequalinium N-(6-Aminohexyl)-5-Chloro-1-Naphthalenesulfonamide Prenylamine Flunarizine (3Z)-N,N-DIMETHYL-2-OXO-3-(4,5,6,7-TETRAHYDRO-1H-INDOL-2-YLMETHYLIDENE)-2,3-DIHYDRO-1H-INDOLE-5-SULFONAMIDE Myristic acid Calcium citrate Calcium citrate Calcium citrate Calcium Phosphate Calcium Phosphate Calcium Phosphate Calcium levulinate Calcium phosphate dihydrate Calcium phosphate dihydrate Calcium phosphate dihydrate
Diseases		Acute myeloid leukemia (AML) Oral cancer Non-small cell lung cancer Multiple myeloma Cervical cancer Kaposi's sarcoma Cholangiocarcinoma Gallbladder cancer Gastric cancer Noonan syndrome and related disorders, including: Noonan syndrome (NS); Leopard syndrome (LS); Noonan syndrome-like with loose anagen hair (NS/LAH); CBL-mutation associated syndrome (CBL); Neurofibromatosis type 1 (NF1); Neurofibromatosis type 2 (NF2); Neurofibromatosis-Noonan syndrome (NFNS); Legius syndrome; Cardiofaciocutaneous syndrome (CFCS); Costello syndrome (CS) Ovarian cancer Hepatocellular carcinoma Thyroid cancer Squamous cell carcinoma Colorectal cancer Endometrial Cancer Craniosynostosis, including: Pfeiffer syndrome; Apert syndrome; Crouzon syndrome; Jackson-Weiss syndrome; Beare-Stevenson syndrome; Muenke craniosynostosis; Saethre-Chotzen syndrome; Craniosynostosis Boston type; Antley-Bixler syndrome; Carpenter syndrome; Craniofrontonasal dysplasia; Noonan syndrome; Baller-Gerold syndrome Pancreatic cancer
GWAS		Alanine aminotransferase levels ( 33547301) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) Dysmenorrheic pain ( 27454463) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514)	Leukocyte telomere length ( 32109421) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872)
Interacting Genes		63 interacting genes: ADH6 ARL6IP5 BCAS3 BCL2 CALM1 CCL5 CCT7 CDK8 DDX47 DDX50 DIRAS3 DNAJA3 EGLN1 EPB42 FANCC FNTA FNTB FRAT2 HEMGN HNRNPC HRAS IGFBP3 IGSF21 IL24 LPAR1 LYPD4 LZTR1 MDFI MOCS2 MT-CO3 MT-CYB NDUFA13 NEDD4 OSGIN1 PDE4DIP PGGT1B PIK3CA PIK3CG PIK3R2 PIP5K1A PPP2CB PSMA3 QDPR RAF1 RALGDS RAP1GDS1 RASGRF2 RASGRP2 RASSF2 RASSF5 RBPMS RGL2 RNF141 SERPINB5 SHOC2 SOX4 STX17 THRSP TNFSF13 UQCRC1 WDR76 ZDHHC17 ZNF189	268 interacting genes: ACADM ACE2 ADCY8 ADCYAP1R1 ADD1 ADD2 AKAP5 AKAP6 AKAP9 AR ARHGEF7 ARLN ARMC1 ASCL2 ATP2B1 ATRX BRWD1 C11orf65 CABIN1 CALCR CALD1 CAMK1 CAMK2G CAMKK1 CAMKK2 CAMTA2 CASP8AP2 CCDC14 CCNA2 CCND1 CCND2 CCNE1 CCP110 CDC37L1 CDC5L CHEK2 CKMT1B CLINT1 CLIP1 CLTB CNGA2 CNN1 CRHR1 CSNK2A1 CSNK2A2 CSNK2B DAPK1 DCTN2 DCUN1D1 DDAH1 DDIT4L DDX21 DDX5 DLG3 DMXL1 DNAJC13 DOCK11 DOCK3 DRC9 DRD2 DST EDF1 EGFR EIF3C ERBB2 ERBB3 ESR1 ESR2 ESRRG EWSR1 FAS FBXO9 FER FKBP3 FKBP4 GAD1 GAD2 GAP43 GCLM GEM GJB1 GLP1R GLP2R GNAS GRB7 GRIN1 GRK1 GRK4 GRK5 GRM3 GRM4 GRM5 GRM7 GSC2 GTF2I H2AX HERC2 HMMR HSP90AA1 HSPA4 HTR2C HUWE1 IDH1 IMMT INSR IQCE IQCN IQGAP1 IQGAP2 IQSEC2 ITGA6 ITPKA ITPKB KCNB1 KCNH1 KCNN1 KCNN2 KCNN3 KCNN4 KCNQ2 KCNQ3 KCNQ5 KDM5C KIF1B KRAS LACTB LINC00839 LMO7 LTF LUC7L LY96 LYST MAPT MATR3 MBIP METAP2 MFHAS1 MIP MORF4L1 MYBPC1 MYCBP2 MYF5 MYF6 MYLK MYO10 MYO5A MYO7A MYO9B MYOD1 MYOG NBR1 NEB NEUROD1 NEXN NOL7 NOS3 NR3C1 NRGN NSMF NT5C2 OBSCN OPALIN OPRM1 OPTN PAM PCNT PCP4 PDCD7 PDE1A PHACTR4 PHKB PHKG1 PIK3C3 PLA2G6 PLCD1 POC5 POLR2B PPEF1 PPEF2 PPIL2 PRDX1 PSMD12 PSMD2 PTAFR PTEN PTH2R PTPRA PUM3 RAB3B RAD23B RALA RALB RANBP2 RDX REL RELA RGS10 RGS2 RGS4 RIT2 RPL13A RPL22 RPS14 RPS15A RPS4Y1 RPS8 RRAD RS1 RYR1 S100B SCAPER SCLT1 SCN1A SCN4A SCN5A SCTR SDCBP SEC61A1 SEC61B SET SF3B1 SLF2 SLTM SNCA SNRPB2 SNTA1 SNX6 SPATA17 SPP1 SQSTM1 SRP14 SRSF5 STAG1 STIM2 STK38 STRN STRN3 STRN4 STX8 SUMO2 SYK SYNE2 SYT1 TBC1D1 TCF3 TCF4 THOP1 TNNI2 TPT1 TRDN TRPC3 TRPV1 TRPV4 TRPV6 TSC2 TTN UBC UBR4 UCHL5 USP16 UTRN VAMP7 VIPR1 XRCC4 YBX1 YWHAE ZBTB24 ZNF280A
Entrez ID		3845	801
HPRD ID		01817	00241
Ensembl ID		ENSG00000133703	ENSG00000198668
Uniprot IDs		I1SRC5 L7RSL8 P01116	B4DJ51 P0DP23 P0DP24 P0DP25 Q96HY3
PDB IDs		1D8D 1D8E 1KZO 1KZP 1N4P 1N4Q 1N4R 1N4S 2MSC 2MSD 2MSE 3GFT 4DSN 4DSO 4EPR 4EPT 4EPV 4EPW 4EPX 4EPY 4L8G 4LDJ 4LPK 4LRW 4LUC 4LV6 4LYF 4LYH 4LYJ 4M1O 4M1S 4M1T 4M1W 4M1Y 4M21 4M22 4NMM 4OBE 4PZY 4PZZ 4Q01 4Q02 4Q03 4QL3 4TQ9 4TQA 4WA7 5F2E 5KYK 5MLA 5MLB 5O2S 5O2T 5OCG 5OCO 5OCT 5TAR 5TB5 5UFE 5UFQ 5UK9 5UQW 5US4 5USJ 5V6S 5V6V 5V71 5V9L 5V9O 5V9U 5VBM 5VP7 5VPI 5VPY 5VPZ 5VQ0 5VQ1 5VQ2 5VQ6 5VQ8 5W22 5WHA 5WHB 5WHD 5WHE 5WLB 5WPM 5XCO 5YXZ 5YY1 6ARK 6ASA 6ASE 6B0V 6B0Y 6BOF 6BP1 6CC9 6CCH 6CCX 6CU6 6E6F 6E6G 6EPL 6EPM 6EPN 6EPO 6EPP 6F76 6FA1 6FA2 6FA3 6FA4 6GJ5 6GJ6 6GJ7 6GJ8 6GOD 6GOE 6GOF 6GOG 6GOM 6GQT 6GQW 6GQX 6GQY 6H46 6H47 6JTN 6JTO 6JTP 6M9W 6MBQ 6MBT 6MBU 6MNX 6MQG 6MQN 6MS9 6MTA 6N2J 6N2K 6O36 6O46 6O4Y 6O4Z 6O51 6O53 6OB2 6OB3 6OIM 6P0Z 6P8W 6P8X 6P8Y 6P8Z 6PGO 6PGP 6PQ3 6PTS 6PTW 6QUU 6QUV 6QUW 6QUX 6T5B 6T5U 6T5V 6TAM 6TAN 6USX 6USZ 6UT0 6V5L 6V65 6V6F 6VC8 6VJJ 6W4E 6W4F 6WGN 6WS2 6WS4 6XGU 6XGV 6XHA 6XHB 6YR8 6YXW 6ZL5 6ZLI 7A1W 7A1X 7A1Y 7A47 7ACA 7ACF 7ACH 7ACQ 7C40 7C41 7EW9 7EWA 7EWB 7EYX 7F0W 7KFZ 7KMR 7KYZ 7LC1 7LC2 7LGI 7LZ5 7MDP 7MQU 7NY8 7O70 7OK3 7OK4 7OO7 7Q9U 7R0M 7R0N 7R0Q 7ROV 7RP2 7RP3 7RP4 7RPZ 7RSC 7RSE 7RT1 7RT2 7RT3 7RT4 7RT5 7SCW 7SCX 7STF 7T1F 7T47 7TLE 7TLG 7TLK 7U8H 7VVB 7W5R 7YCC 7YCE 7YUZ 7YV1 8AFB 8AFC 8AFD 8AQ5 8AQ7 8AZR 8AZV 8AZX 8AZY 8AZZ 8B00 8B69 8B6I 8B78 8BE3 8BE4 8BE5 8BLR 8CPR 8CX5 8DGS 8DGT 8DNI 8DNJ 8DNK 8DVG 8EBZ 8ECR 8EDY 8EER 8EIE 8EPW 8EZG 8F0M 8FMI 8FMJ 8FMK 8G42 8G47 8G4F 8G4H 8G9P 8G9Q 8I5C 8I5D 8I5E 8JGD 8JHL 8JJS 8K4T 8K4V 8K50 8ONV 8PI0 8PIY 8QU8 8QUG 8QVU 8QW6 8QW7 8R7W 8R7X 8RNI 8RRO 8S8C 8STM 8STN 8T4V 8T71 8T72 8T73 8T74 8T75 8TBF 8TBH 8TBJ 8TBK 8TBL 8TBM 8TBN 8TVK 8TXE 8TXG 8TXH 8TXJ 8TXK 8TY2 8TY8 8TY9 8UDR 8UN3 8UN4 8UN5 8V39 8V3A 8VGQ 8VJZ 8VR9 8VRA 8VRB 8WTE 8WUL 8X6R 8YIV 8YJ2 9AX6 9BFW 9BFY 9BFZ 9BG1 9BHO 9BHP 9BHQ 9BI1 9BI2 9C15 9E5D 9E5F 9E9H 9E9I 9KPM 9KPN	1CDL 1CLL 1CTR 1IWQ 1J7O 1J7P 1K90 1K93 1L7Z 1LVC 1NKF 1PK0 1S26 1SK6 1SW8 1UP5 1WRZ 1XFU 1XFV 1XFW 1XFX 1XFY 1XFZ 1Y6W 1YR5 1YRT 1YRU 1ZOT 1ZUZ 2BE6 2F3Y 2F3Z 2HF5 2I08 2JZI 2K0E 2K0F 2K0J 2K61 2KNE 2KUG 2KUH 2L53 2L7L 2LGF 2LL6 2LL7 2LQC 2LQP 2LV6 2M0J 2M0K 2M55 2MG5 2N27 2N6A 2N77 2N8J 2R28 2V01 2V02 2VAY 2W73 2WEL 2X0G 2Y4V 3BYA 3DVE 3DVJ 3DVK 3DVM 3EVV 3EWT 3EWV 3G43 3HR4 3J41 3O77 3O78 3OXQ 3SUI 3UCT 3UCW 3UCY 4BW7 4BW8 4BYF 4DCK 4DJC 4GOW 4JPZ 4JQ0 4L79 4LZX 4M1L 4OVN 4Q57 4Q5U 4UMO 4UPU 4V0C 5COC 5DBR 5DOW 5DSU 5GGM 5I0I 5J03 5J8H 5JQA 5JTH 5K7L 5K8Q 5NIN 5OEO 5TP5 5TP6 5V02 5V03 5V7X 5VMS 5WBX 5WC5 5WSU 5WSV 6B8L 6B8M 6B8N 6B8P 6B8Q 6BUT 6C1D 6C1G 6C1H 6CNM 6CNN 6CNO 6DAD 6DAE 6DAF 6DAH 6E2F 6E2G 6EEB 6FEG 6FEH 6GDK 6GDL 6HCS 6HR1 6JI8 6JII 6JIU 6JIY 6JRS 6JV2 6K4K 6K4L 6K4R 6K67 6M2W 6M7H 6MUD 6MUE 6N5W 6O5G 6OS4 6PAW 6PBX 6PBY 6PLM 6S5T 6SZ5 6TV7 6U39 6U3A 6U3B 6U3D 6UZZ 6V00 6V01 6X32 6X33 6X35 6X36 6XXF 6XXX 6XY3 6XYR 6Y4O 6Y4P 6Y94 6Y95 6YA9 6YNS 6YNU 6ZBI 7AUG 7BF1 7BF2 7BYL 7BYM 7BYN 7CR3 7CR4 7CR7 7KL5 7L8V 7MIR 7MIS 7PPO 7PQE 7PSZ 7PU9 7SHQ 7SX3 7SX4 7T2Q 7TCI 7TCP 7TZC 7U9T 7UA3 7UA4 7VMB 7VNP 7VNQ 7VNR 7VUO 7VUR 7VUS 7VUT 7VUU 7VVD 7VVH 7WJI 7WR3 7WR4 7WR5 7WZS 7XN4 7XN5 7XN6 7XNI 7XNK 7XNL 7XNN 7ZRP 7ZRQ 8AHS 8B6Q 8BD2 8BFG 8DGH 8DGK 8DUJ 8DVE 8EOW 8EP0 8EP1 8FNY 8FO6 8GM4 8GM5 8IJK 8J00 8J01 8J02 8J03 8J04 8J05 8J07 8JFK 8K9Z 8KA0 8KA1 8ODZ 8OE0 8OE4 8PB1 8SIK 8SIM 8SIN 8UXL 8UXM 8W4U 8X43 8XJI 8XKH 8XLF 8XLH 8XO1 8XYA 8XYB 8Y40 9CUI 9CUK 9E17 9JQI 9K8W 9K8X
Enriched GO Terms of Interacting Partners?		Regulation Of Intracellular Signal Transduction Intracellular Signaling Cassette Protein Prenyltransferase Activity Intracellular Signal Transduction Regulation Of Signal Transduction Regulation Of Small GTPase Mediated Signal Transduction Regulation Of MAPK Cascade Protein Prenylation Phosphatidylinositol 3-kinase Complex, Class IA GTPase Regulator Activity Prenyltransferase Activity Acetyltransferase Activator Activity Channel Inhibitor Activity Regulation Of Cell Communication Regulation Of Signaling CAAX-protein Geranylgeranyltransferase Activity CAAX-protein Geranylgeranyltransferase Complex Protein Farnesyltransferase Activity Protein Farnesyltransferase Complex Ras Protein Signal Transduction Signal Transduction Protein Farnesylation Positive Regulation Of Intracellular Signal Transduction Small GTPase-mediated Signal Transduction Regulation Of Programmed Cell Death Protein Geranylgeranyltransferase Activity Phosphatidylinositol 3-kinase Complex, Class IB Cytoplasm Glial Cell Development Adenylate Cyclase Activator Activity Quinol-cytochrome-c Reductase Activity Positive Regulation Of Apoptotic Process Positive Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Apoptotic Process Regulation Of Smooth Muscle Cell Migration Positive Regulation Of Signal Transduction Positive Regulation Of Cell Communication Positive Regulation Of Signaling Positive Regulation Of Programmed Cell Death Protein Geranylgeranylation Insulin Receptor Signaling Pathway Autophagosome Membrane Docking 1-phosphatidylinositol-4-phosphate 3-kinase Activity 1-phosphatidylinositol-4,5-bisphosphate 3-kinase Activity Intracellular Glucose Homeostasis Neuromuscular Junction Development Apoptotic Process Phosphatidylinositol 3-kinase Complex Negative Regulation Of Fibroblast Apoptotic Process Protein Phosphatase Binding	Calmodulin Binding Cytosol Plasma Membrane Cytoplasm Regulation Of Signaling Regulation Of Cell Communication Intracellular Signal Transduction Signal Transduction Neuron Projection Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Intracellular Signaling Cassette Regulation Of Synaptic Plasticity Regulation Of Biological Quality Response To Calcium Ion Chemical Synaptic Transmission Biological_process Actin Binding Synaptic Signaling Regulation Of Signal Transduction Metal Ion Transport Trans-synaptic Signaling Positive Regulation Of Cell Communication Axon Cellular Response To Calcium Ion Regulation Of Membrane Potential Regulation Of Transport Positive Regulation Of Signaling Monoatomic Ion Channel Activity Synapse Small Conductance Calcium-activated Potassium Channel Activity Response To Metal Ion Regulation Of System Process Regulation Of Metal Ion Transport Cell Cortex Neuronal Cell Body Calcium Ion Homeostasis Cellular Response To Oxygen-containing Compound Calcium Ion Transport Estrogen Response Element Binding Regulation Of Intracellular Signal Transduction Identical Protein Binding Kinase Activity Response To Hormone Regulation Of Calcium Ion Transport Cellular Response To Metal Ion Cell Communication Muscle System Process Calcium/calmodulin-dependent Protein Kinase Activity Signaling Focal Adhesion
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