KIR2DL2 and CD93

Number of citations of the paper that reports this interaction (PubMedID 9476117)
0

Data Source:
HPRD (in vitro)

		KIR2DL2	CD93
Description		killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2	CD93 molecule
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GO Annotations	Cellular Component	Plasma Membrane Membrane	Plasma Membrane Cell Surface Membrane Secretory Granule Membrane Cytoplasmic Vesicle Specific Granule Membrane Tertiary Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	Protein Binding	Complement Component C1q Complex Binding Calcium Ion Binding Protein Binding Carbohydrate Binding Signaling Receptor Activity
	Biological Process	Immune Response-regulating Signaling Pathway	Angiogenesis Phagocytosis Cell Adhesion Macrophage Activation Cell-cell Adhesion
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Neutrophil degranulation
Drugs
Diseases
GWAS			Liver enzyme levels (alanine transaminase) ( 24124411) Obesity-related traits ( 23251661) Venous thromboembolism ( 26888256 31676865)
Interacting Genes		2 interacting genes: CD93 HLA-C	25 interacting genes: ARHGAP15 BAG6 C1QA COL1A1 COL1A2 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 COPS5 F12 GIPC1 ITGB1 KIR2DL2 KNG1 MBL2 MMRN2 MSN MYD88 RANBP1 SCYL1 TENT5A UBQLN2
Entrez ID		3803	22918
HPRD ID		16080	00396
Ensembl ID			ENSG00000125810
Uniprot IDs		A0A0C4ZN23 P43627 Q6H2H0 Q8N742	Q9NPY3
PDB IDs		1EFX 2DL2 2DLI 6PA1 8TMU	8A59 8IVD
Enriched GO Terms of Interacting Partners?		Secretory Granule Membrane TAP Binding MHC Class I Protein Complex Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-independent Cell Surface Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class Ib Complement Component C1q Complex Binding Positive Regulation Of T Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Lumenal Side Of Endoplasmic Reticulum Membrane Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Positive Regulation Of Natural Killer Cell Mediated Immunity Antigen Processing And Presentation Of Endogenous Antigen Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Peptide Antigen Binding Regulation Of T Cell Mediated Cytotoxicity Antigen Processing And Presentation Of Peptide Antigen ER To Golgi Transport Vesicle Membrane Regulation Of Natural Killer Cell Mediated Immunity Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Leukocyte Mediated Cytotoxicity Tertiary Granule Membrane Ficolin-1-rich Granule Membrane Macrophage Activation Positive Regulation Of Cell Killing Positive Regulation Of T Cell Mediated Immunity Phagocytic Vesicle Membrane Specific Granule Membrane Antigen Processing And Presentation Regulation Of T Cell Mediated Immunity Immune System Process Regulation Of Leukocyte Mediated Cytotoxicity Recycling Endosome Membrane Phagocytosis Receptor Ligand Activity Positive Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Positive Regulation Of Lymphocyte Mediated Immunity Positive Regulation Of Adaptive Immune Response Myeloid Leukocyte Activation	Collagen Trimer Collagen Type IV Trimer Extracellular Matrix Structural Constituent Conferring Tensile Strength Collagen-activated Tyrosine Kinase Receptor Signaling Pathway Collagen-activated Signaling Pathway Extracellular Matrix Structural Constituent Extracellular Matrix Basement Membrane Endoplasmic Reticulum Lumen Extracellular Matrix Organization Extracellular Structure Organization Extracellular Region Platelet-derived Growth Factor Binding Response To Amino Acid Collagen Type I Trimer Enzyme-linked Receptor Protein Signaling Pathway Cellular Response To Amino Acid Stimulus Signal Transduction Signaling Receptor Binding Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Cell Surface Receptor Signaling Pathway Fibrillar Collagen Trimer Inflammatory Response Glomerular Basement Membrane Development Molecular Adaptor Activity Skin Morphogenesis Regulation Of Proteolysis Endothelial Cell Migration Misfolded Protein Binding Positive Regulation Of ERAD Pathway Regulation Of Response To Endoplasmic Reticulum Stress Symbiont Cell Surface Protease Binding Cell Migration Involved In Sprouting Angiogenesis Regulation Of ERAD Pathway Killing Of Cells Of Another Organism Angiogenesis Cellular Response To Low-density Lipoprotein Particle Stimulus Killing By Host Of Symbiont Cells Leukocyte Activation Leukocyte Activation Involved In Inflammatory Response Complement Activation, Classical Pathway Cellular Response To Vitamin E Protein Heterotrimerization Neuromuscular Junction Development Basement Membrane Organization Regulation Of Anatomical Structure Morphogenesis Regulation Of Wound Healing Zymogen Activation Cellular Response To Lipoprotein Particle Stimulus
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