KCNJ6 and STATH

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KCNJ6	STATH
Description		potassium inwardly rectifying channel subfamily J member 6	statherin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Plasma Membrane Voltage-gated Potassium Channel Complex Membrane Monoatomic Ion Channel Complex	Extracellular Region
	Molecular Function	Inward Rectifier Potassium Channel Activity Protein Binding G-protein Activated Inward Rectifier Potassium Channel Activity	Protein Binding Extracellular Matrix Constituent, Lubricant Activity Structural Constituent Of Tooth Enamel Hydroxyapatite Binding
	Biological Process	Monoatomic Ion Transport Potassium Ion Transport Monoatomic Ion Transmembrane Transport Regulation Of Monoatomic Ion Transmembrane Transport Potassium Ion Import Across Plasma Membrane	Ossification Regulation Of Bone Mineralization Negative Regulation Of Bone Mineralization Biomineral Tissue Development Defense Response To Bacterium Saliva Secretion
Pathways		Activation of G protein gated Potassium channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs		Ethanol Halothane Ifenprodil Isavuconazole
Diseases
GWAS		Body size at age 10 ( 32376654) Clostridioides difficle infection ( 33841421) Electroencephalographic traits in alcoholism ( 22554406) Response to placebo treatment in childhood asthma (FVC change) ( 31557306) Rosacea symptom severity ( 29771307)
Interacting Genes		71 interacting genes: ADRB2 AIG1 APOD BCL2L2 BET1 BIRC5 C14orf180 CMAS CMTM5 CNPY3 COL4A5 CXXC5 DLG1 DRD2 EDDM3B ERG28 FAM20B FIS1 FUNDC2 FXYD6 GABBR1 GIPC1 HMOX2 ICMT ITGAM KCNJ3 KCNJ9 LEPROTL1 LPAR3 LPCAT2 MAP1S MIP MYO15B NINJ2 ORMDL2 PEX11G PEX16 PICK1 PLLP PMP22 PNLIPRP1 PTPRD RPRM RPS6KA2 RTP2 SCAMP4 SCARF1 SCD SERTM1 STATH STRIT1 SYT3 THSD7B TM6SF2 TMEM107 TMEM120B TMEM203 TMEM208 TMEM218 TMPPE TNFRSF10C TSPO2 UBIAD1 UNC50 UPK1B VSTM1 XIAP YIPF1 YIPF6 ZBTB38 ZDHHC24	30 interacting genes: AQP6 C16orf92 DERL3 ERGIC3 FAM209A FAM210B FCRL3 FKBP7 GET3 GPR152 GPR42 KCNJ6 LEUTX MRM1 MTIF3 OPRPN OVGP1 REEP4 SAR1A SGPL1 SLC10A1 SLC10A6 SLC35H1 SLC39A2 SLC61A1 SPNS3 TFAM TLCD4 TMEM80 TMX2
Entrez ID		3763	6779
HPRD ID		02929	01696
Ensembl ID		ENSG00000157542	ENSG00000126549
Uniprot IDs		P48051	P02808
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Presynaptic Membrane Trans-synaptic Signaling Synaptic Signaling Endoplasmic Reticulum Membrane Protein Binding Endoplasmic Reticulum Chemical Synaptic Transmission Negative Regulation Of Dopamine Secretion G-protein Activated Inward Rectifier Potassium Channel Activity Compact Myelin Inward Rectifier Potassium Channel Complex Regulation Of Sodium Ion Transport Protein Targeting Regulation Of Presynaptic Membrane Potential Regulation Of Monoatomic Ion Transport Nervous System Process Involved In Regulation Of Systemic Arterial Blood Pressure Golgi Trans Cisterna Negative Regulation Of Synaptic Transmission	Bile Acid:sodium Symporter Activity
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