ZNF699 and HRC

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF699	HRC
Description		zinc finger protein 699	histidine rich calcium binding protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Lumen Cytosol Sarcoplasmic Reticulum Z Disc Sarcoplasmic Reticulum Lumen
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Calcium Ion Binding Protein Binding Transmembrane Transporter Binding ATPase Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II	Regulation Of Heart Rate Muscle Contraction Positive Regulation Of Heart Rate Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Positive Regulation Of Heart Contraction Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Positive Regulation Of Relaxation Of Cardiac Muscle Regulation Of Calcium Ion Transmembrane Transport
Pathways		Generic Transcription Pathway	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs
Diseases
GWAS
Interacting Genes		7 interacting genes: DVL3 EFEMP2 HEXIM2 HRC KRTAP10-3 KRTAP10-9 SRRM4	2 interacting genes: TRDN ZNF699
Entrez ID		374879	3270
HPRD ID		13429	00818
Ensembl ID		ENSG00000196110	ENSG00000130528
Uniprot IDs		Q32M78	P23327
PDB IDs
Enriched GO Terms of Interacting Partners?			Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Positive Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Sarcoplasmic Reticulum Lumen Positive Regulation Of Cell Communication By Electrical Coupling Junctional Sarcoplasmic Reticulum Membrane Regulation Of Cardiac Muscle Cell Membrane Potential Release Of Sequestered Calcium Ion Into Cytosol By Endoplasmic Reticulum Junctional Membrane Complex Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of Cell Communication By Electrical Coupling Sarcoplasmic Reticulum Calcium Ion Transport Endoplasmic Reticulum Membrane Organization Heart Contraction Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Heart Process Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Sarcoplasmic Reticulum Membrane Release Of Sequestered Calcium Ion Into Cytosol Negative Regulation Of Sequestering Of Calcium Ion Cytoplasmic Microtubule Organization Sarcoplasmic Reticulum
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