KCNC1 and KCNV2

Number of citations of the paper that reports this interaction (PubMedID 12060745)
35

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KCNC1	KCNV2
Description		potassium voltage-gated channel subfamily C member 1	potassium voltage-gated channel modifier subfamily V member 2
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Voltage-gated Potassium Channel Complex Cell Surface Membrane Axon Dendrite Axolemma Neuron Projection Membrane Dendrite Membrane Neuronal Cell Body Membrane Monoatomic Ion Channel Complex Presynaptic Membrane Cell Projection Neuronal Cell Body Axon Terminus Calyx Of Held Synapse Postsynaptic Membrane	Plasma Membrane Voltage-gated Potassium Channel Complex Membrane Monoatomic Ion Channel Complex
	Molecular Function	Monoatomic Ion Channel Activity Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Potassium Channel Activity Protein Binding Kinesin Binding Gated Channel Activity Transmembrane Transporter Binding Voltage-gated Monoatomic Ion Channel Activity Involved In Regulation Of Presynaptic Membrane Potential	Monoatomic Ion Channel Activity Voltage-gated Potassium Channel Activity Potassium Channel Activity Protein Binding Potassium Channel Regulator Activity
	Biological Process	Action Potential Monoatomic Ion Transport Potassium Ion Transport Response To Toxic Substance Response To Light Intensity Response To Auditory Stimulus Response To Amine Cerebellum Development Optic Nerve Development Globus Pallidus Development Corpus Callosum Development Monoatomic Ion Transmembrane Transport Regulation Of Monoatomic Ion Transmembrane Transport Positive Regulation Of Monoatomic Ion Transmembrane Transport Response To Potassium Ion Protein Homooligomerization Protein Tetramerization Transmembrane Transport Cellular Response To Xenobiotic Stimulus Response To Fibroblast Growth Factor Potassium Ion Transmembrane Transport Regulation Of Presynaptic Membrane Potential Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Potassium Ion Transmembrane Transport Response To Nerve Growth Factor	Action Potential Monoatomic Ion Transport Potassium Ion Transport Monoatomic Ion Transmembrane Transport Protein Homooligomerization Transmembrane Transport Potassium Ion Transmembrane Transport
Pathways		Voltage gated Potassium channels	Voltage gated Potassium channels
Drugs		Enflurane Promethazine Miconazole Dalfampridine	Enflurane Promethazine Miconazole
Diseases			Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD)
GWAS		Body mass index ( 26426971) Night sleep phenotypes ( 27126917) Opioid sensitivity ( 24143882)	Alzheimer's disease (age of onset) ( 22005931) Blood trace element (Se levels) ( 23720494) Inflammatory biomarkers (multivariate analysis) ( 33110245) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Vascular endothelial growth factor levels ( 21757650 26910538)
Interacting Genes		7 interacting genes: ANK3 KCNG3 KCNH1 KCNV2 LPAR3 TMBIM6 TRARG1	4 interacting genes: ANKRD28 KCNB1 KCNC1 KCNF1
Entrez ID		3746	169522
HPRD ID		15936	12126
Ensembl ID		ENSG00000129159	ENSG00000168263
Uniprot IDs		P48547	Q8TDN2
PDB IDs		7PHH 7PHI 7PHK 7PHL 7PQT 7PQU 8F1C 8F1D 8QUC 8QUD
Enriched GO Terms of Interacting Partners?		Voltage-gated Potassium Channel Activity Potassium Channel Activity Voltage-gated Potassium Channel Complex Regulation Of Metal Ion Transport Action Potential Regulation Of Membrane Potential Regulation Of Monoatomic Ion Transport Monoatomic Ion Channel Complex Potassium Ion Transmembrane Transport Transmembrane Transport Monoatomic Ion Channel Activity Potassium Ion Transport Metal Ion Transport Monoatomic Cation Transmembrane Transport Inorganic Cation Transmembrane Transport Regulation Of Biological Quality Plasma Membrane Inorganic Ion Transmembrane Transport Regulation Of Monoatomic Cation Transmembrane Transport Monoatomic Cation Transport Monoatomic Ion Transmembrane Transport Potassium Channel Regulator Activity Regulation Of Monoatomic Ion Transmembrane Transport Establishment Of Protein Localization To Plasma Membrane Monoatomic Ion Transport Regulation Of Potassium Ion Transmembrane Transport Negative Regulation Of Cation Transmembrane Transport Axon Negative Regulation Of Monoatomic Ion Transmembrane Transport Cyclic Nucleotide Binding Neuron Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Regulation Of Potassium Ion Transport Negative Regulation Of Monoatomic Ion Transport Positive Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential Maintenance Of Protein Location In Plasma Membrane Endoribonuclease Inhibitor Activity Negative Regulation Of Transmembrane Transport Positive Regulation Of Cell Communication By Electrical Coupling Vesicle-mediated Transport To The Plasma Membrane Membrane Lysophosphatidic Acid Receptor Activity Regulation Of Transport Cellular Response To Metal Ion Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential Negative Regulation Of Calcium Ion Transport Into Cytosol Cellular Response To Magnesium Ion Positive Regulation Of Monoatomic Ion Transport Negative Regulation Of IRE1-mediated Unfolded Protein Response Glucose Import In Response To Insulin Stimulus Protein Localization To Plasma Membrane	Voltage-gated Potassium Channel Activity Potassium Channel Activity Voltage-gated Potassium Channel Complex Action Potential Monoatomic Ion Channel Complex Potassium Ion Transmembrane Transport Monoatomic Ion Channel Activity Potassium Ion Transport Protein Homooligomerization Delayed Rectifier Potassium Channel Activity Neuronal Cell Body Membrane Protein Complex Oligomerization Dendrite Membrane Potassium Channel Regulator Activity Regulation Of Membrane Potential Regulation Of Potassium Ion Transport Metal Ion Transport Monoatomic Cation Transmembrane Transport Inorganic Cation Transmembrane Transport Inorganic Ion Transmembrane Transport Monoatomic Cation Transport Monoatomic Ion Transmembrane Transport Transmembrane Transporter Binding Monoatomic Ion Transport Positive Regulation Of Norepinephrine Secretion Globus Pallidus Development Gated Channel Activity Neuron Projection Membrane Clustering Of Voltage-gated Potassium Channels Transmembrane Transport Postsynaptic Membrane Cell Projection Protein-containing Complex Assembly Positive Regulation Of Long-term Synaptic Depression Proximal Dendrite Protein-containing Complex Organization Protein Serine/threonine Phosphatase Complex Response To Metal Ion Voltage-gated Monoatomic Ion Channel Activity Involved In Regulation Of Presynaptic Membrane Potential Regulation Of Metal Ion Transport Cholinergic Synapse Neuronal Ion Channel Clustering Neuronal Cell Body Regulation Of Norepinephrine Secretion Positive Regulation Of Catecholamine Secretion Regulation Of Transport Axolemma Optic Nerve Development Axon Regulation Of Motor Neuron Apoptotic Process
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