DPPA3 and IPO5

Number of citations of the paper that reports this interaction (PubMedID 17143267)
0

Data Source:
HPRD (in vitro, in vivo)

		DPPA3	IPO5
Description		developmental pluripotency associated 3	importin 5
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GO Annotations	Cellular Component	Female Pronucleus Male Pronucleus Nucleus Cytoplasm	Nucleus Nuclear Pore Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Cytosol Membrane Nuclear Membrane
	Molecular Function	Protein Binding Histone H3K9me2/3 Reader Activity	RNA Binding GTPase Inhibitor Activity Protein Binding Nuclear Localization Sequence Binding Small GTPase Binding Nuclear Import Signal Receptor Activity
	Biological Process	Chromatin Organization Epigenetic Programing Of Female Pronucleus	Cytoplasmic Pattern Recognition Receptor Signaling Pathway Protein Import Into Nucleus NLS-bearing Protein Import Into Nucleus Ribosomal Protein Import Into Nucleus Intracellular Protein Transport Protein Transport Positive Regulation Of Protein Import Into Nucleus Negative Regulation Of Cell Cycle Cellular Response To Amino Acid Stimulus
Pathways		Chromatin modifications during the maternal to zygotic transition (MZT)	vRNP Assembly
Drugs
Diseases
GWAS		Borderline personality disorder ( 28632202) White matter hyperintensities in ischemic stroke ( 26674333)	Peripheral artery disease ( 26488411) Smooth-surface caries ( 24556642)
Interacting Genes		15 interacting genes: CFTR DEPDC5 DYNLL1 DYNLL2 HAUS7 IPO5 KRT27 KRT76 NUP62 PLEKHG4 SERTAD3 SYCE1L TFIP11 TRIB3 ZNF618	31 interacting genes: ACD CAB39 CDC42 DPPA3 DTNBP1 GPRASP3 H1-0 NOSIP NRIP1 NUP153 NUP214 NUP62 NUP98 OGT PRRC2B PTEN RAG2 RAN RANBP2 RNF10 RPL13 RPL23 RPL23A RPL5 RPL7 RPS7 SRP19 SUMO2 TERF1 TINF2 WASL
Entrez ID		359787	3843
HPRD ID		16331	03597
Ensembl ID		ENSG00000187569	ENSG00000065150
Uniprot IDs		Q6W0C5	B3KWG6 O00410 Q9BVS9
PDB IDs		8WMS 8XV7 8XV8	6XTE 6XU2 9IM6
Enriched GO Terms of Interacting Partners?			Cytosolic Ribosome Import Into Nucleus Protein Import Into Nucleus Cytoplasmic Translation Establishment Of Protein Localization To Organelle Nuclear Pore Nucleus Ribonucleoprotein Complex Protein Localization To Nucleus Cytosolic Large Ribosomal Subunit Structural Constituent Of Nuclear Pore RNA Binding Protein Localization To Organelle Nuclear Export Shelterin Complex Nuclear Transport Nucleocytoplasmic Transport RNA Transport Structural Constituent Of Ribosome RNA Export From Nucleus Nucleolus Negative Regulation Of Ubiquitin Protein Ligase Activity Nuclear Telomere Cap Complex Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Ubiquitin-protein Transferase Activity Nucleoplasm Ribosome Nuclear Inclusion Body Ubiquitin Ligase Inhibitor Activity Telomere Capping Nuclear Pore Nuclear Basket Nucleobase-containing Compound Transport Nuclear Envelope Translation MRNA Transport Intracellular Transport Intracellular Protein Transport Dendritic Spine Morphogenesis Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Cellular Localization Negative Regulation Of Telomere Maintenance Via Telomerase Nuclear Localization Sequence Binding Negative Regulation Of Protein Ubiquitination Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Ubiquitin-protein Transferase Activity Organelle Localization Nuclear Pore Cytoplasmic Filaments Negative Regulation Of RNA Export From Nucleus Telomeric DNA Binding Negative Regulation Of Telomere Maintenance Via Telomere Lengthening
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