LILRA5 and DNAAF3

		LILRA5	DNAAF3
Description		leukocyte immunoglobulin like receptor A5	dynein axonemal assembly factor 3
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Cell Surface Membrane	Extracellular Region Cytoplasm Dynein Axonemal Particle
	Molecular Function	Inhibitory MHC Class I Receptor Activity
	Biological Process	Immune System Process Immune Response-regulating Signaling Pathway Cytokine-mediated Signaling Pathway Negative Regulation Of Interleukin-12 Production Negative Regulation Of Interleukin-13 Production Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Interleukin-10 Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Tumor Necrosis Factor Production Positive Regulation Of MAPK Cascade Innate Immune Response Positive Regulation Of Inflammatory Response Positive Regulation Of Cell Activation Positive Regulation Of Calcium Ion Transport Positive Regulation Of Protein Tyrosine Kinase Activity	Cell Morphogenesis Spermatogenesis Determination Of Left/right Symmetry Brain Development Heart Development Determination Of Adult Lifespan Male Gonad Development Cell Projection Organization Lung Development Multicellular Organism Growth Motile Cilium Assembly Axonemal Dynein Complex Assembly Seminiferous Tubule Development Cerebrospinal Fluid Circulation
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) HDL cholesterol ( 25961943) High density lipoprotein cholesterol levels ( 33339817)
Interacting Genes		1 interacting genes: DNAAF3	7 interacting genes: ACP4 BRSK1 LENG9 LILRA5 SIGLEC12 SIGLEC14 ZNF606
Entrez ID		353514	352909
HPRD ID		06924	14185
Ensembl ID		ENSG00000187116	ENSG00000167646
Uniprot IDs		A6NI73	Q8N9W5
PDB IDs		2D3V
Enriched GO Terms of Interacting Partners?		Dynein Axonemal Particle Axonemal Dynein Complex Assembly Motile Cilium Assembly Extracellular Transport Epithelial Cilium Movement Involved In Extracellular Fluid Movement Cerebrospinal Fluid Circulation Seminiferous Tubule Development Determination Of Adult Lifespan Lung Development Male Gonad Development Determination Of Bilateral Symmetry Multicellular Organism Growth Determination Of Left/right Symmetry Gonad Development Cell Morphogenesis Cilium Movement Reproductive Structure Development Microtubule-based Transport Tube Development Brain Development Heart Development Cilium Assembly Cilium Organization Pattern Specification Process Microtubule-based Movement Plasma Membrane Bounded Cell Projection Assembly Cell Projection Assembly Developmental Growth	Sialic Acid Binding Negative Regulation Of ERBB4 Signaling Pathway Peptidyl-tyrosine Dephosphorylation Involved In Inactivation Of Protein Kinase Activity
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