LEUTX and MRPL57

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LEUTX	MRPL57
Description		leucine twenty homeobox	mitochondrial ribosomal protein L57
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Ribosome Mitochondrial Large Ribosomal Subunit Ribosome Ribonucleoprotein Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding	Structural Constituent Of Ribosome Protein Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II	Translation Mitochondrial Translation
Pathways		Zygotic genome activation (ZGA)	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial ribosome-associated quality control
Drugs
Diseases
GWAS		Macular thickness ( 30535121)
Interacting Genes		46 interacting genes: AGPAT4 AIG1 AQP2 AQP3 ASGR1 C1GALT1 C1QL4 C3orf52 CDS2 CMTM3 CMTM5 CNIH1 CNIH3 CXCL9 EMP3 ENTPD3 FAM24B FZD7 GOSR2 KIR2DL3 LAT MRPL57 MS4A1 NAPB NDRG4 OLFM4 PLP1 PNLIPRP1 PRB1 SLC13A3 SLC30A8 SLC41A2 STATH TF TMEM128 TMEM147 TMEM187 TMEM254 TMEM60 TMEM97 TSPO TTPA UNC93B1 VAMP4 ZFPL1 ZNF646	3 interacting genes: CIDEB CREB3 LEUTX
Entrez ID		342900	78988
HPRD ID			14736
Ensembl ID		ENSG00000213921	ENSG00000173141
Uniprot IDs		A8MZ59	Q9BQC6
PDB IDs			3J7Y 3J9M 5OOL 5OOM 6I9R 6NU2 6NU3 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5H 7A5I 7A5J 7A5K 7L08 7L20 7O9K 7O9M 7ODR 7ODS 7ODT 7OF0 7OF2 7OF3 7OF4 7OF5 7OF6 7OF7 7OG4 7OI6 7OI7 7OI8 7OI9 7OIA 7OIB 7OIC 7OID 7OIE 7PD3 7PO4 7QH6 7QH7 7QI4 7QI5 7QI6 8ANY 8K2A 8K2B 8OIR 8OIT 8PK0 8QSJ 8QU5 8RRI 8XT0 8XT1 8XT2 8XT3
Enriched GO Terms of Interacting Partners?		Membrane	Positive Regulation Of Deacetylase Activity CCR1 Chemokine Receptor Binding Release From Viral Latency Lipid Droplet Fusion Positive Regulation Of Monocyte Chemotaxis Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Induction Of Positive Chemotaxis CAMP Response Element Binding Protein Binding Positive Regulation Of Positive Chemotaxis Execution Phase Of Apoptosis COPI-coated Vesicle Phosphatidic Acid Binding COPII Vesicle Coat Lipid Transfer Activity Protein-lipid Complex Assembly COPII-coated Vesicle Cargo Loading Plasma Lipoprotein Particle Assembly Very-low-density Lipoprotein Particle Assembly
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