KRT27 and ZC3H14

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRT27	ZC3H14
Description		keratin 27	zinc finger CCCH-type containing 14
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome	Nucleus Nucleolus Cytoplasm Nuclear Speck Dendrite Cytoplasm Axon Cytoplasm Ribonucleoprotein Complex
	Molecular Function	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis	RNA Binding MRNA 3'-UTR Binding Protein Binding Poly(A) Binding Zinc Ion Binding Pre-mRNA Binding Metal Ion Binding
	Biological Process	Morphogenesis Of An Epithelium Epithelial Cell Differentiation Hair Follicle Morphogenesis Intermediate Filament Organization	Spermatogenesis Cell Differentiation Regulation Of MRNA Stability MRNA Stabilization Spliceosome-depend Formation Of Circular RNA
Pathways		Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		Asthma ( 31959851)	Visceral fat ( 30942860)
Interacting Genes		139 interacting genes: AARD ABI2 AMOT ARFIP1 ARHGEF6 ATP6V1D BCAS2 BEX2 BFSP2 C19orf44 C1orf216 C21orf58 CCBE1 CCDC138 CCDC146 CCDC185 CCDC187 CCDC22 CCDC68 CCHCR1 CCNC CEP95 CFAP58 COX5B DPPA3 DTNB DUSP26 EXOC3L1 EXOSC5 FAM107A FAM110A FMNL2 GADD45GIP1 GFAP GNG13 GOLGA1 GPS2 GSTK1 HAPLN2 HDAC4 HGS HOXB9 HSPBP1 ICA1L IGF1R INSR INSRR JOSD1 KANK2 KIAA1217 KLHL38 KRT1 KRT2 KRT20 KRT3 KRT4 KRT5 KRT6A KRT6B KRT6C KRT7 KRT71 KRT72 KRT74 KRT75 KRT76 KRT77 KRT78 KRT79 KRT8 KRT81 KRT82 KRT83 KRT85 KRT86 LKAAEAR1 LMNTD2 MATR3 MBD3L2 MID2 MORN4 MOS MTMR9 NDC80 NDUFAF3 NTAQ1 NUP54 NUP58 ODAD3 OIP5 PBX3 PCDHB14 PNN POLL PPP1R18 PRPH PSMC5 RASAL3 RBM41 RCOR3 RNF39 RTP5 RUNX1T1 SCNM1 SDHAF1 SEMA4C SLC22A5 SLIRP SMARCC2 SMARCD1 SMARCE1 SSC5D SSX3 SUFU SUOX TBRG4 TEAD4 TEDC2 TEX28 THAP7 TNNT1 TRAF3IP3 TRIML2 TSKS TTC23 TXLNB TXN2 USHBP1 USP2 VPS37C WASHC3 XRCC4 ZC3H14 ZFYVE26 ZNF3 ZNF580 ZNF581 ZNF669 ZNF80	9 interacting genes: DDIT3 DYNLT3 EXOC7 HOOK2 ITCH KRT20 KRT27 NEDD4 UBC
Entrez ID		342574	79882
HPRD ID		17244	13348
Ensembl ID		ENSG00000171446	ENSG00000100722
Uniprot IDs		Q7Z3Y8	G3V256 Q6PJT7
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Organization Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Keratinization Keratin Filament Supramolecular Fiber Organization Cytoskeleton Organization Protein Binding Organelle Organization Insulin Receptor Activity Structural Constituent Of Cytoskeleton Insulin Receptor Complex Intermediate Filament Cytoskeleton Structural Molecule Activity Insulin Receptor Substrate Binding Epidermis Development Brahma Complex NpBAF Complex RSC-type Complex NBAF Complex Phosphatidylinositol 3-kinase Binding Nucleosome Disassembly Insulin Binding	Intrinsic Apoptotic Signaling Pathway In Response To Nitrosative Stress Negative Regulation Of Determination Of Dorsal Identity Modification-dependent Protein Catabolic Process Cytoplasm Proteolysis Involved In Protein Catabolic Process CHOP-ATF4 Complex CHOP-ATF3 Complex Regulation Of Autophagy Cytosol Receptor Internalization Channel Inhibitor Activity Protein K63-linked Ubiquitination Protein Monoubiquitination Formation Of Structure Involved In A Symbiotic Process Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Organization ATF6-mediated Unfolded Protein Response Macromolecule Catabolic Process GDF15-GFRAL Signaling Pathway HRI-mediated Signaling Involuntary Skeletal Muscle Contraction Blood Vessel Maturation CHOP-C/EBP Complex Establishment Of Protein Localization Negative Regulation Of Interleukin-4 Production Response To Nitrosative Stress Diaphragm Contraction Smooth Muscle Cell Proliferation Cellular Response To Nitrosative Stress Ubiquitin-dependent Protein Catabolic Process Vascular Associated Smooth Muscle Cell Proliferation Proteolysis Vascular Associated Smooth Muscle Cell Migration Sodium Channel Inhibitor Activity Cell Cortex Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Import Into Cell Vesicle-mediated Transport Endocytosis Phosphoserine Residue Binding Nuclear Receptor-mediated Corticosteroid Signaling Pathway Vacuolar Transport Lysosomal Transport Beta-2 Adrenergic Receptor Binding Phosphothreonine Residue Binding Receptor-mediated Endocytosis Protein Ubiquitination
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