IDH3B and RAB35

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		IDH3B	RAB35
Description		isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta	RAB35, member RAS oncogene family
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GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix Isocitrate Dehydrogenase Complex (NAD+)	Endosome Cytosol Plasma Membrane Clathrin-coated Pit Endosome Membrane Membrane Clathrin-coated Vesicle Clathrin-coated Endocytic Vesicle Membrane Cell Projection Membrane Cytoplasmic Vesicle Melanosome Intercellular Bridge Clathrin-coated Endocytic Vesicle Recycling Endosome Membrane Extracellular Exosome
	Molecular Function	Magnesium Ion Binding Isocitrate Dehydrogenase (NAD+) Activity Protein Binding Electron Transfer Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor NAD Binding	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Phosphatidylinositol-4,5-bisphosphate Binding Hydrolase Activity GDP Binding Metal Ion Binding
	Biological Process	Tricarboxylic Acid Cycle Isocitrate Metabolic Process	Mitotic Cytokinesis Intracellular Protein Localization Protein Transport Endosomal Transport Antigen Processing And Presentation Neuron Projection Development Endocytic Recycling Rab Protein Signal Transduction Protein Localization To Endosome Plasma Membrane To Endosome Transport Cellular Response To Nerve Growth Factor Stimulus
Pathways		Citric acid cycle (TCA cycle)	TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs		NADH
Diseases		Retinitis pigmentosa (RP)
GWAS			Heel bone mineral density ( 30598549)
Interacting Genes		7 interacting genes: ATXN2 IDH3A IDH3G MAPK6 PRMT1 RAB35 TNFRSF9	12 interacting genes: APP CALCOCO2 CBR3 DENND1B GNPAT IDH3B MPHOSPH9 PTPRS TBPL1 TRIM54 USP32 WDCP
Entrez ID		3420	11021
HPRD ID		05163	05010
Ensembl ID		ENSG00000101365	ENSG00000111737
Uniprot IDs		A0A087WZN1 A0A087X2E5 O43837	Q15286
PDB IDs		6KDE 6KDF 6KDY 6KE3 7CE3 8GRB 8GRD 8GRU 8GS5	3TW8 6EKK 6IF2 6IF3
Enriched GO Terms of Interacting Partners?		Isocitrate Dehydrogenase (NAD+) Activity Isocitrate Dehydrogenase Complex (NAD+) Isocitrate Metabolic Process Tricarboxylic Acid Metabolic Process Tricarboxylic Acid Cycle NAD Binding Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor GATOR1 Complex Binding Septin Cytoskeleton Protein-arginine Omega-N Monomethyltransferase Activity N-methyltransferase Activity Histone H4R3 Methyltransferase Activity Positive Regulation Of Hemoglobin Biosynthetic Process Peptidyl-arginine Methylation Regulation Of Hemoglobin Biosynthetic Process Mitogen-activated Protein Kinase P38 Binding Response To Methionine Protein-arginine Omega-N Asymmetric Methyltransferase Activity Histone H4 Methyltransferase Activity Cellular Response To Methionine Magnesium Ion Binding
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