CCDC158 and DESI1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CCDC158	DESI1
Description		coiled-coil domain containing 158	desumoylating isopeptidase 1
Image		No pdb structure
GO Annotations	Cellular Component	Early Endosome Clathrin-coated Vesicle	Nucleus Cytoplasm Cytosol Protein-containing Complex
	Molecular Function	Protein Binding Clathrin Binding	Protein Binding Peptidase Activity Palmitoyl-(protein) Hydrolase Activity Hydrolase Activity DeSUMOylase Activity Identical Protein Binding Long-chain Fatty Acyl-CoA Hydrolase Activity Importin-alpha Family Protein Binding
	Biological Process	Receptor-mediated Endocytosis	Proteolysis Protein Export From Nucleus Protein Desumoylation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Macromolecule Depalmitoylation
Pathways
Drugs
Diseases
GWAS		Chronic kidney disease ( 20383146) Estimated glomerular filtration rate ( 31015462)	General cognitive ability ( 29844566) Meat-related diet ( 32066663) Neuroticism ( 29255261) Refractive error ( 32231278)
Interacting Genes		11 interacting genes: C1orf216 DESI1 FCHSD2 GPSM1 NAGK NUTF2 SGF29 SH3GLB2 TBC1D21 TNPO2 UBQLN2	35 interacting genes: ABI3 AGR3 CCDC158 CDIP1 CDSN CENPM CTAG1A CTAG1B CTAG2 DAZAP2 ERP29 EVI2B FGF7 GOLM1 KLRF1 MEOX2 NME3 NT5C3A PRR5 RBX1 RNF4 RPS27A SHISA4 SHISA5 SLC25A17 SMIM21 TAS2R41 UBA52 UBB UBC UBQLN1 UBQLNL UHRF2 XPO1 ZBTB46
Entrez ID		339965	27351
HPRD ID		13395	18590
Ensembl ID		ENSG00000163749	ENSG00000100418
Uniprot IDs		A0A804HIY6 Q5M9N0	Q6ICB0
PDB IDs			3EBQ
Enriched GO Terms of Interacting Partners?		Nuclear Import Signal Receptor Activity Stereocilium Shaft Establishment Of Protein Localization Nuclear Transport Nucleocytoplasmic Transport Small GTPase Binding Protein Export From Nucleus N-acetylglucosamine Kinase Activity Muramyl Dipeptide Kinase Activity Establishment Of Protein Localization To Organelle Negative Regulation Of G Protein-coupled Receptor Internalization N-acylmannosamine Kinase Activity N-acetylmannosamine Metabolic Process	Protein Tag Activity TRNA Threonylcarbamoyladenosine Metabolic Process Modification-dependent Protein Catabolic Process Endocytic Vesicle Membrane Ubiquitin Protein Ligase Binding Mitochondrial Outer Membrane Proteolysis Involved In Protein Catabolic Process Protein Ubiquitination Regulation Of Granulocyte Differentiation Protein Modification By Small Protein Conjugation Vesicle
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