CENATAC and PPIL3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CENATAC	PPIL3
Description		centrosomal AT-AC splicing factor	peptidylprolyl isomerase like 3
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GO Annotations	Cellular Component	Cytoplasm Centrosome Cytoskeleton	Nucleoplasm Spliceosomal Complex Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Isomerase Activity
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Negative Regulation Of Centrosome Duplication Regulation Of Protein Catabolic Process Chromosome Separation	MRNA Splicing, Via Spliceosome MRNA Processing Protein Folding RNA Splicing
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Breast cancer ( 27117709) Breast cancer (estrogen-receptor negative) ( 27117709) Triptolide cytotoxicity ( 26121980)
Interacting Genes		7 interacting genes: MESD MRPL38 NAT10 NDOR1 PPIL3 SIRT1 ZNF114	20 interacting genes: ALS2 CDK11B CENATAC DMRTB1 MAIP1 MOB4 NOP58 NUP107 PCBP1 PHC1 RPS13 SHARPIN SLU7 SPATS2L SRPK1 STRADB TAB2 TAB3 WDR12 YTHDF1
Entrez ID		338657	53938
HPRD ID		13234	15163
Ensembl ID		ENSG00000186166	ENSG00000240344
Uniprot IDs		Q86UT8	A0A024R3V4 A0A0S2Z5A8 Q9H2H8
PDB IDs		8Y6O	1XYH 2OJU 2OK3 8C6J
Enriched GO Terms of Interacting Partners?		Regulation Of Centrosome Cycle NAD-dependent Protein Decrotonylase Activity Histone H4K12 Deacetylase Activity, Hydrolytic Mechanism Protein Acetylation Negative Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Regulation Of Centrosome Duplication Maintenance Of Nucleus Location Histone Decrotonylase Activity, NAD-dependent Histone H3K14 Deacetylase Activity, NAD-dependent Negative Regulation Of Cellular Response To Testosterone Stimulus Histone H3K Deacetylase Activity NADPH-iron-sulfur [2Fe-2S] Protein Oxidoreductase Activity TRNA Acetylation MRNA N-acetyltransferase Activity TRNA Cytidine N4-acetyltransferase Activity TRNA Wobble Cytosine Modification RRNA Acetylation Involved In Maturation Of SSU-rRNA 18S RRNA Cytidine N-acetyltransferase Activity NAD-dependent Protein Lysine Delactylase Activity Regulation Of Cellular Response To Testosterone Stimulus Behavioral Response To Starvation Negative Regulation Of Peptidyl-lysine Acetylation Histone H4K16 Deacetylase Activity, NAD-dependent Histone H3K9 Deacetylase Activity, NAD-dependent NAD-dependent Protein-lysine Depropionylase Activity Negative Regulation Of Prostaglandin Biosynthetic Process Protein Depropionylation Positive Regulation Of Macrophage Apoptotic Process ENoSc Complex Positive Regulation Of CAMP-dependent Protein Kinase Activity NADPH-hemoprotein Reductase Activity Negative Regulation Of Protein Acetylation Negative Regulation Of Triglyceride Biosynthetic Process Triglyceride Mobilization Pyrimidine Dimer Repair By Nucleotide-excision Repair HLH Domain Binding Oxidoreductase Activity, Acting On NAD(P)H, Heme Protein As Acceptor Histone Deacetylase Activity, NAD-dependent Regulation Of CAMP-dependent Protein Kinase Activity RDNA Heterochromatin Chromosome, Telomeric Region Keratin Filament Binding Protein Folding RDNA Heterochromatin Formation Regulation Of Endodeoxyribonuclease Activity Stress-induced Premature Senescence NAD-dependent Protein Lysine Deacetylase Activity Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Ovulation From Ovarian Follicle
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