UBAC2 and MIR182

Number of citations of the paper that reports this interaction (PubMedID 32913183)
70

Data Source:
BioGRID (affinity chromatography technology, unspecified method)

		UBAC2	MIR182
Description		UBA domain containing 2	microRNA 182
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Extracellular Space
	Molecular Function	Serine-type Endopeptidase Activity Protein Binding	MRNA Base-pairing Post-transcriptional Repressor Activity
	Biological Process	Wnt Signaling Pathway Protein Localization To Endoplasmic Reticulum Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Retrograde Protein Transport, ER To Cytosol	Positive Regulation Of Cytokine Production Positive Regulation Of Gene Expression Positive Regulation Of Cell Migration MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By Inhibition Of Translation Epigenetic Regulation Of Gene Expression Cholesterol Homeostasis Positive Regulation Of Cholesterol Biosynthetic Process Positive Regulation Of Fatty Acid Biosynthetic Process Cellular Response To Cholesterol Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Negative Regulation Of Epithelial Cell Apoptotic Process Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Negative Regulation Of Vascular Associated Smooth Muscle Cell Migration Negative Regulation Of Vascular Associated Smooth Muscle Cell Dedifferentiation
Pathways
Drugs
Diseases
GWAS		Asthma ( 32296059 31959851 31619474 31361310 30929738) Asthma (childhood onset) ( 31036433 30929738) Basal cell carcinoma ( 21700618) Behcet's disease ( 33393726) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Cuneus cortex volume ( 31530798) Eosinophil count ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Inflammatory bowel disease ( 28067908) Medication use (adrenergics, inhalants) ( 31015401) Metabolite levels ( 23823483) Neutrophil percentage of granulocytes ( 27863252) Psoriasis ( 28537254) Sum eosinophil basophil counts ( 27863252) Systemic lupus erythematosus ( 33536424) Tinnitus ( 33742053)	Bipolar disorder ( 31043756)
Interacting Genes		5 interacting genes: CALCOCO2 GET4 LMO7 MIR182 UBC	1 interacting genes: UBAC2
Entrez ID		337867	406958
HPRD ID		11429
Ensembl ID		ENSG00000134882	ENSG00000207990
Uniprot IDs		A8K2S7 Q8NBM4
PDB IDs
Enriched GO Terms of Interacting Partners?			Negative Regulation Of Protein Exit From Endoplasmic Reticulum Regulation Of Retrograde Protein Transport, ER To Cytosol Negative Regulation Of Retrograde Protein Transport, ER To Cytosol Protein Localization To Endoplasmic Reticulum Regulation Of Protein Exit From Endoplasmic Reticulum Negative Regulation Of Intracellular Protein Transport Negative Regulation Of Intracellular Transport Serine-type Endopeptidase Activity Regulation Of Intracellular Protein Transport Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Establishment Of Protein Localization Negative Regulation Of Protein Transport Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Protein Localization Regulation Of Intracellular Transport Wnt Signaling Pathway Regulation Of Canonical Wnt Signaling Pathway
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