HLF and DBP

Number of citations of the paper that reports this interaction (PubMedID 10073576)
0

Data Source:
HPRD (in vivo, in vitro)

		HLF	DBP
Description		HLF transcription factor, PAR bZIP family member	D-box binding PAR bZIP transcription factor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm RNA Polymerase II Transcription Regulator Complex	Chromatin Nucleus RNA Polymerase II Transcription Regulator Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Double-stranded DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Skeletal Muscle Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Rhythmic Process	Liver Development Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Rhythmic Process
Pathways			Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes
Drugs
Diseases
GWAS		Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced) ( 24236485) Bipolar disorder ( 31043756 33263727) HDL cholesterol levels ( 32203549) Hematocrit ( 32888494) Hemoglobin ( 32888494) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917) Platelet distribution width ( 32888494) Red blood cell count ( 32888494) Serum uric acid levels ( 30993211) Urate levels ( 23263486 31578528 31985003) Urate levels in obese individuals ( 25811787) Waist circumference ( 28552196) Weight ( 28552196) Zinc levels ( 26025379)	Bipolar disorder ( 21926972) Crohn's disease ( 23128233) Elevated serum carcinoembryonic antigen levels ( 24941225) Lymphocyte count ( 32888494) Non-oily fish consumption ( 32066663) Oily fish consumption ( 32066663) Pork consumption ( 32066663)
Interacting Genes		11 interacting genes: ABCC3 BMAL1 CCDC59 CREBBP DBP HNF4G MYB MYL4 PPAN TET2 USO1	12 interacting genes: ATF3 BATF BATF2 BATF3 CEBPA CEBPG CLOCK DDIT3 EP300 EPAS1 HLF TEF
Entrez ID		3131	1628
HPRD ID		00797	00497
Ensembl ID		ENSG00000108924	ENSG00000105516
Uniprot IDs		Q16534	Q10586
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription By RNA Polymerase II Rhythmic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of DNA-templated Transcription DNA-binding Transcription Factor Activity Positive Regulation Of RNA Metabolic Process Golgi Vesicle Docking Icosanoid Transmembrane Transporter Activity Glucuronoside Transmembrane Transporter Activity Glucuronoside Transport Energy Homeostasis Histone H3K27 Acetyltransferase Activity Positive Regulation Of Hepatic Stellate Cell Proliferation Myosin II Heavy Chain Binding Oxidative Stress-induced Premature Senescence Histone H3K18 Acetyltransferase Activity N-terminal Peptidyl-lysine Acetylation Peptide Lactyltransferase (CoA-dependent) Activity Positive Regulation Of Testosterone Secretion DNA 5-methylcytosine Dioxygenase Activity	Chromatin DNA-binding Transcription Factor Activity RNA Polymerase II Transcription Regulator Complex Integrated Stress Response Signaling RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Myeloid Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Response To Stress Positive Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Sequence-specific Double-stranded DNA Binding Mononuclear Cell Differentiation Leukocyte Differentiation Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Intracellular Signal Transduction Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Sequence-specific DNA Binding Myeloid Dendritic Cell Differentiation Positive Regulation Of Biosynthetic Process Transcription Regulator Complex CHOP-ATF3 Complex Intracellular Signaling Cassette Myeloid Dendritic Cell Activation Positive Regulation Of DNA-binding Transcription Factor Activity Regulation Of Macromolecule Metabolic Process CHOP-C/EBP Complex Positive Regulation Of Macromolecule Metabolic Process Response To Stress Dendritic Cell Differentiation Myeloid Leukocyte Differentiation Cell Differentiation Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Regulation Of DNA-binding Transcription Factor Activity Nucleus RNA Polymerase II-specific DNA-binding Transcription Factor Binding Developmental Process Cellular Developmental Process
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