ANXA6 and TPD52

Number of citations of the paper that reports this interaction (PubMedID 15576473)
0

Data Source:
HPRD (in vivo)

		ANXA6	TPD52
Description		annexin A6	tumor protein D52
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Lysosomal Membrane Plasma Membrane Focal Adhesion Vesicle Membrane Membrane Extracellular Matrix Late Endosome Membrane Melanosome Perinuclear Region Of Cytoplasm Extracellular Exosome	Cytoplasm Endoplasmic Reticulum Perinuclear Region Of Cytoplasm
	Molecular Function	Phosphatidylserine Binding Calcium Ion Binding Protein Binding GTP Binding Calcium-dependent Phospholipid Binding Lipid Binding Ligand-gated Monoatomic Ion Channel Activity Cholesterol Binding Identical Protein Binding Calcium-dependent Protein Binding	Calcium Ion Binding Protein Binding Protein Homodimerization Activity
	Biological Process	Calcium Ion Transport Regulation Of Muscle Contraction Monoatomic Ion Transmembrane Transport Negative Regulation Of Sequestering Of Calcium Ion Mitochondrial Calcium Ion Homeostasis Apoptotic Signaling Pathway	Positive Regulation Of Cell Population Proliferation Anatomical Structure Morphogenesis B Cell Differentiation Secretion
Pathways		Smooth Muscle Contraction	Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Inflammatory skin disease ( 25574825) Lymphocyte count ( 32888494) Psoriasis ( 25574825 25903422) Psoriatic arthritis ( 26626624)	Allergic rhinitis ( 30013184) Allergy ( 27182965) Asthma ( 34103634 31959851 31619474 31361310 29273806 27182965) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Fasting glucose ( 34059833) Kawasaki disease ( 33772158) Lapatinib-induced hepatotoxicity ( 25987243) Metabolite levels (HVA/MHPG ratio) ( 23319000) Metabolite levels (Pyroglutamine) ( 23934736) Rheumatoid arthritis ( 30423114 24390342) Self-reported allergy ( 23817569)
Interacting Genes		19 interacting genes: A2M CDC73 CEBPA CR2 ERBB2 IL16 LINC00632 LINC01554 MLH1 MTNR1B OGT PDE4B RASA1 RHOU S100A1 S100B SMURF1 SNCA TPD52	17 interacting genes: ANXA6 AR MAL2 MAPK3 SENP2 SH3GLB1 SOCS2 SPG21 SPOP SRPK2 STUB1 THAP4 TPD52L1 TPD52L2 TPD52L3 TTPA UBC
Entrez ID		309	7163
HPRD ID		00231	04963
Ensembl ID		ENSG00000197043	ENSG00000076554
Uniprot IDs		A0A0S2Z2Z6 A0A0S2Z377 P08133	P55327
PDB IDs		1M9I
Enriched GO Terms of Interacting Partners?		Regulation Of Multicellular Organismal Process Regulation Of Immune System Process Positive Regulation Of Multicellular Organismal Process Signaling Receptor Binding Calcium-dependent Protein Binding Cellular Developmental Process Negative Regulation Of Complement Activation Signal Transduction Regulation Of Developmental Process Cellular Response To Epinephrine Stimulus S100 Protein Binding Response To Epinephrine Regulation Of Cell Morphogenesis Regulation Of Anatomical Structure Morphogenesis Regulation Of Complement Activation Leukocyte Activation Regulation Of Cell Shape Developmental Process Regulation Of Cell Activation Regulation Of Signal Transduction Cell Activation Enzyme Binding Regulation Of Ubiquitin-dependent Protein Catabolic Process Cell Surface Receptor Signaling Pathway RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Protein Homodimerization Activity Positive Regulation Of Inflammatory Response Regulation Of Programmed Cell Death Regulation Of Biological Quality Late Recombination Nodule Meiotic Metaphase I Homologous Chromosome Alignment Negative Regulation Of Neuron Apoptotic Process Tau Protein Binding Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Engulfment Of Target By Autophagosome Growth Factor Binding B Cell Activation Regulation Of Humoral Immune Response Positive Regulation Of Proteolysis Carbohydrate Homeostasis Glucose Homeostasis Response To Lipid Lymphocyte Activation Negative Regulation Of Complement Activation, Lectin Pathway	Cytoplasm Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway ERBB Signaling Pathway Mammary Gland Alveolus Development Positive Regulation Of Macroautophagy Animal Organ Formation ERBB2 Signaling Pathway Lipid Binding Enzyme-linked Receptor Protein Signaling Pathway Regulation Of Protein Stability Protein Modification By Small Protein Conjugation Insulin-like Growth Factor Receptor Signaling Pathway Prostate Induction Male Somatic Sex Determination Protein Modification Process Positive Regulation Of Autophagy Regulation Of Macroautophagy Negative Regulation Of Establishment Of Blood-brain Barrier Post-translational Protein Modification Positive Regulation Of Chaperone-mediated Protein Complex Assembly Peroxynitrite Isomerase Activity Protein Localization To Vacuolar Membrane Response To Epidermal Growth Factor
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