EHD3 and SNAP29

Number of citations of the paper that reports this interaction (PubMedID 11423532)
0

Data Source:
HPRD (two hybrid)

		EHD3	SNAP29
Description		EH domain containing 3	synaptosome associated protein 29
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endosome Early Endosome Cytosol Plasma Membrane Focal Adhesion Cilium Endosome Membrane Membrane Ciliary Pocket Membrane Endocytic Vesicle Cell Projection Perinuclear Region Of Cytoplasm Recycling Endosome Membrane Ciliary Membrane	Golgi Membrane Autophagosome Membrane Cytoplasm Mitochondrion Autophagosome Golgi Apparatus Centrosome Cytosol Plasma Membrane Cilium Membrane Ciliary Pocket Membrane SNARE Complex Cytoplasmic Vesicle Azurophil Granule Membrane Cell Projection Ciliary Membrane Presynapse
	Molecular Function	Nucleotide Binding Nucleic Acid Binding Calcium Ion Binding Protein Binding ATP Binding GTP Binding Protein-macromolecule Adaptor Activity Metal Ion Binding	SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Receptor Recycling Endocytosis Protein Transport Cell Projection Organization Endocytic Recycling Early Endosome To Golgi Transport Protein Homooligomerization Regulation Of Cardiac Muscle Contraction Cilium Assembly Protein Localization To Plasma Membrane Regulation Of Cardiac Muscle Cell Membrane Potential Golgi To Lysosome Transport Regulation Of Golgi Organization Regulation Of Cardiac Conduction	Exocytosis Vesicle Targeting Autophagy Protein Transport Synaptic Vesicle Priming Autophagosome Membrane Docking Cell Projection Organization Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Cilium Assembly Membrane Fusion Autophagosome Maturation
Pathways		Factors involved in megakaryocyte development and platelet production	Neutrophil degranulation Intra-Golgi traffic
Drugs
Diseases			Cerebral dysgenesis, neuropathy, ichthyosis, and palmoplantar keratoderma syndrome; CEDNIK syndrome
GWAS		Estradiol levels ( 22675492) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Lymphocyte percentage of white cells ( 32888494) Male-pattern baldness ( 28196072) Mean platelet volume ( 22139419 32888494 27863252 24026423 19820697) Metabolite levels ( 23823483) Monocyte count ( 32888494) Neutrophil count ( 32888494) Platelet count ( 27863252 32888494 22139419) Platelet distribution width ( 27863252 32888494) Plateletcrit ( 27863252 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 27863252 32888494) White blood cell count ( 32888494)
Interacting Genes		4 interacting genes: ARL6IP1 EHD1 SNAP29 SNCA	24 interacting genes: AP2A1 ATF4 CD7 DNAJC5 EHD1 EHD3 FAM9B ITSN2 KIFC3 LURAP1 NAPB NTAQ1 RASSF7 STX12 STX17 STX1A STX1B STX2 STX3 STX6 STX7 TXNRD3 VAMP1 VAMP7
Entrez ID		30845	9342
HPRD ID		16170	11968
Ensembl ID		ENSG00000013016	ENSG00000099940
Uniprot IDs		Q9NZN3	O95721
PDB IDs			4WY4 7BV6
Enriched GO Terms of Interacting Partners?		Ciliary Pocket Membrane Synaptic Vesicle Priming Ciliary Membrane Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Regulation Of Amine Transport Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Membrane Organization Organelle Organization Cellular Component Assembly Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Positive Regulation Of Transport Negative Regulation Of Serotonin Uptake Transporter Regulator Activity Negative Regulation Of Chaperone-mediated Autophagy Negative Regulation Of Dopamine Metabolic Process Exocytosis Regulation Of Serotonin Uptake Positive Regulation Of L-glutamate Import Across Plasma Membrane Mitochondrial ATP Synthesis Coupled Electron Transport Presynapse Cuprous Ion Binding Protein Complex Oligomerization Protein-containing Complex Organization Regulation Of Chaperone-mediated Autophagy Negative Regulation Of Thrombin-activated Receptor Signaling Pathway Dopamine Uptake Involved In Synaptic Transmission Response To Growth Factor Negative Regulation Of Catecholamine Metabolic Process Cellular Response To Growth Factor Stimulus Response To Iron(II) Ion Dopamine Biosynthetic Process Protein-containing Complex Assembly Regulation Of Dopamine Uptake Involved In Synaptic Transmission Vesicle-mediated Transport Negative Regulation Of Cellular Respiration Cell Projection Negative Regulation Of Oxidative Phosphorylation Cilium Assembly Cilium Organization Establishment Of Protein Localization Autophagosome Membrane Docking Positive Regulation Of Endocytic Recycling Positive Regulation Of Cholesterol Storage Platelet Dense Tubular Network Membrane Sec61 Translocon Complex	SNAP Receptor Activity SNARE Complex Vesicle Fusion Organelle Membrane Fusion SNARE Binding Organelle Fusion Membrane Fusion Vesicle Docking Vesicle-mediated Transport Organelle Localization By Membrane Tethering Membrane Docking Vesicle Organization Intracellular Protein Transport Endomembrane System Intracellular Transport Establishment Of Localization In Cell Protein Transport Cellular Localization Establishment Of Protein Localization Vesicle-mediated Transport In Synapse Membrane Organization Exocytosis Intracellular Protein Localization Organelle Localization Regulation Of Synaptic Vesicle Priming Syntaxin Binding Secretion By Cell Synaptic Vesicle Organelle Organization Synaptic Vesicle Membrane Endocytic Recycling Secretion Ciliary Pocket Membrane Presynaptic Active Zone Membrane Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Recycling Endosome Membrane Regulated Exocytosis Synaptic Vesicle Exocytosis Calcium-ion Regulated Exocytosis Synaptic Vesicle Endocytosis Endosomal Transport Presynaptic Endocytosis Vesicle-mediated Transport To The Plasma Membrane Golgi Vesicle Transport ATP-dependent Protein Binding Chloride Channel Inhibitor Activity Plasma Membrane Azurophil Granule Membrane Regulation Of Vesicle-mediated Transport Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane
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