POLR1H and IVNS1ABP

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		POLR1H	IVNS1ABP
Description		RNA polymerase I subunit H	influenza virus NS1A binding protein
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GO Annotations	Cellular Component	DNA-directed RNA Polymerase Complex Nucleus Nucleoplasm Nucleolus RNA Polymerase I Complex	Nucleus Nucleoplasm Transcription Regulator Complex Spliceosomal Complex Cytoplasm Cytosol Cytoskeleton Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Nucleic Acid Binding DNA-directed RNA Polymerase Activity Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Nucleobase-containing Compound Metabolic Process DNA-templated Transcription Termination Of RNA Polymerase I Transcription	Transcription By RNA Polymerase III MRNA Processing RNA Splicing Response To Virus Negative Regulation Of Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination
Drugs
Diseases
GWAS			Lead levels ( 26025379)
Interacting Genes		18 interacting genes: APOA1 ATXN2 CIC DUSP1 FHL3 GFI1B GPR20 HAX1 IL15 IVNS1ABP MAPK8IP2 NONO SACS SERPINA3 TNS2 TRIML2 UBE2I ZNF593	12 interacting genes: AHR CHD3 ENO1 KLHL20 NSD3 PFN2 POLR1H RPL6 SYNCRIP TRA2B TRIM14 VIM
Entrez ID		30834	10625
HPRD ID		09601	10004
Ensembl ID		ENSG00000066379	ENSG00000116679
Uniprot IDs		Q2L6J2 Q9P1U0	Q9Y6Y0
PDB IDs		7OB9 7OBA 7OBB 7VBA 7VBB 7VBC 8A43	5YY8 6N34 6N3H
Enriched GO Terms of Interacting Partners?			Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Nucleus RNA Binding Regulation Of Macromolecule Metabolic Process Cytosolic Aryl Hydrocarbon Receptor Complex Type II Interferon Binding Histone H3K4 Dimethyltransferase Activity Histone H3K27 Dimethyltransferase Activity Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Macromolecule Biosynthetic Process Nuclear Aryl Hydrocarbon Receptor Complex Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Metabolic Process Cellular Response To Type II Interferon Protein K33-linked Ubiquitination Phagocytic Vesicle Cellular Response To 2,3,7,8-tetrachlorodibenzodioxine Phosphopyruvate Hydratase Complex Phosphopyruvate Hydratase Activity Termination Of RNA Polymerase I Transcription Histone H3K27 Trimethyltransferase Activity Response To Type II Interferon
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