NRBP1 and CIMIP5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NRBP1	CIMIP5
Description		nuclear receptor binding protein 1	ciliary microtubule inner protein 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cell Cortex Endomembrane System Membrane Lamellipodium Cell Projection	Cilium Cell Projection
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Homodimerization Activity	Protein Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport DNA Damage Response
Pathways		Nuclear Receptor transcription pathway
Drugs
Diseases
GWAS		Bone mineral density (total hip) ( 29883787) Creatinine levels ( 31015462) Crohn's disease ( 28067908) Hypertriglyceridemia ( 23505323) Inflammatory bowel disease ( 28067908) Takayasu arteritis ( 25604533)
Interacting Genes		17 interacting genes: BCL2L13 BTG3 CDKN1A CIMIP5 CSNK2B GADD45A GSK3B LRIF1 MLF1 PPP1CC RAC3 RIBC2 SNX31 SORBS3 TIAM1 TK1 TSC22D4	5 interacting genes: CFTR GSTA4 NOL10 NRBP1 SPP1
Entrez ID		29959	130813
HPRD ID		05819	08051
Ensembl ID		ENSG00000115216	ENSG00000150873
Uniprot IDs		F8W6G1 Q9UHY1	Q96LR7
PDB IDs
Enriched GO Terms of Interacting Partners?		Intracellular Signaling Cassette Wnt Signaling Pathway Regulation Of Dopaminergic Neuron Differentiation	Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport Positive Regulation Of Hormone Secretion Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Positive Regulation Of Estradiol Secretion Regulation Of Estradiol Secretion Positive Regulation Of Enamel Mineralization Regulation Of Hormone Secretion Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Response To Ketone Transepithelial Water Transport Steroid Metabolic Process Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Androgen Catabolic Process Cellular Response To Testosterone Stimulus Response To 2,3,7,8-tetrachlorodibenzodioxine Amelogenesis Response To Macrophage Colony-stimulating Factor Positive Regulation Of Secretion By Cell ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Regulation Of Monoatomic Anion Transport Positive Regulation Of Secretion Epithelial Fluid Transport Positive Regulation Of Bone Resorption Negative Regulation Of Collateral Sprouting Negative Regulation Of Axon Regeneration Negative Regulation Of Neuron Projection Regeneration Golgi-associated Vesicle Membrane Hormone Catabolic Process Cellular Response To Forskolin Response To Forskolin Chloride Transmembrane Transporter Activity Sperm Capacitation Bicarbonate Transport Cellular Response To Lipid Regulation Of Collateral Sprouting Decidualization Small Molecule Binding Steroid Catabolic Process Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Water Transport Androgen Metabolic Process
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