SERTAD3 and TBCE

		SERTAD3	TBCE
Description		SERTA domain containing 3	tubulin folding cofactor E
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Cytoplasm Cytoskeleton Microtubule
	Molecular Function	Protein Binding	Protein Binding Alpha-tubulin Binding Protein-folding Chaperone Binding
	Biological Process	Regulation Of DNA-templated Transcription Negative Regulation Of Cell Growth Positive Regulation Of DNA-templated Transcription	Microtubule Cytoskeleton Organization Protein Folding Tubulin Complex Assembly Post-chaperonin Tubulin Folding Pathway Mitotic Spindle Organization Axonogenesis Adult Locomotory Behavior Post-embryonic Development Muscle Atrophy Developmental Growth Peripheral Nervous System Neuron Axonogenesis
Pathways			Post-chaperonin tubulin folding pathway
Drugs
Diseases			Kenny-Caffey syndrome Hypoparathyroidism-retardation-dysmorphism syndrome; Sanjad-Sakati syndrome
GWAS		Mean reticulocyte volume ( 32888494) Otitis media ( 27632927) Otitis media (chronic) ( 27632927) Otitis media (recurrent) ( 27632927)	Adiposity ( 19557161) Blood protein levels ( 30072576) First year height change in growth hormone-treated short stature ( 32652002) Household income (MTAG) ( 31844048)
Interacting Genes		44 interacting genes: ANKRD11 BEX2 BFSP2 C1orf216 CCNC CENPP CREBBP CTNNAL1 DPPA3 FAAP20 FBXO44 FCHSD2 GTPBP3 HGS IL16 IMP3 KANK2 KLHL42 KPNA2 MBD3 MED25 MSGN1 NDN NPPB P4HA3 PICK1 PKN1 PRKAA2 RPA2 RTP5 SMARCD1 SNRPB SPG11 SUOX TASOR2 TBCE TLE5 TNPO2 TPRX1 TRAPPC6A TXN UBL5 USHBP1 ZGPAT	7 interacting genes: AKT1 EIF2B2 OGT PRDM2 SERTAD3 TBCD TUBA4A
Entrez ID		29946	6905
HPRD ID		15327	05381
Ensembl ID		ENSG00000167565	ENSG00000284770
Uniprot IDs		Q9UJW9	A0A2R8Y6Q1 Q15813
PDB IDs			4ICU 4ICV
Enriched GO Terms of Interacting Partners?			Regulation Of Translational Initiation Regulation Of Translation TOR Signaling Negative Regulation Of Protein Ubiquitination Translation Negative Regulation Of Translational Initiation Phosphatidylinositol-3,4,5-trisphosphate Binding Response To Heat Positive Regulation Of Translational Initiation Positive Regulation Of TOR Signaling Positive Regulation Of TORC1 Signaling Regulation Of TRNA Methylation Response To Peptide Hormone TORC1 Signaling Translational Initiation Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Positive Regulation Of Proteolysis Carbohydrate Homeostasis Response To Rapamycin Positive Regulation Of Protein Localization To Endoplasmic Reticulum Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Nitric-oxide Synthase Regulator Activity Positive Regulation Of RNA Biosynthetic Process Glucose Homeostasis Regulation Of Proteasomal Protein Catabolic Process Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Negative Regulation Of SREBP Signaling Pathway Response To Insulin-like Growth Factor Stimulus Cytoplasmic Translation Response To Temperature Stimulus Negative Regulation Of Fatty Acid Beta-oxidation Positive Regulation Of TORC2 Signaling TRNA Stabilization Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To Hydrogen Peroxide Regulation Of Protein Localization To Cell Periphery Potassium Channel Activator Activity Regulation Of Protein Ubiquitination Mammalian Oogenesis Stage RNA (guanine-N7)-methylation Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of TORC1 Signaling Negative Regulation Of Fatty Acid Transport Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Long-chain Fatty Acid Import Across Plasma Membrane Cellular Response To Peptide Regulation Of Glucose Metabolic Process Response To Hormone Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Regulation Of TOR Signaling
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