TFPT and CNN1

Number of citations of the paper that reports this interaction (PubMedID 27107012)
72

Data Source:
BioGRID (two hybrid)

		TFPT	CNN1
Description		TCF3 fusion partner	calponin 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Ino80 Complex	Cytoskeleton Focal Adhesion Actin Cytoskeleton
	Molecular Function	DNA Binding Protein Binding	Actin Binding Protein Binding Calmodulin Binding Actin Filament Binding
	Biological Process	Telomere Maintenance Regulation Of DNA Replication DNA Repair Regulation Of DNA Repair DNA Recombination Chromatin Remodeling Apoptotic Process DNA Damage Response Regulation Of Chromosome Organization Positive Regulation Of Apoptotic Process Positive Regulation Of DNA Repair Positive Regulation Of DNA-templated Transcription Regulation Of Embryonic Development Regulation Of Cell Cycle Regulation Of DNA Strand Elongation Apoptotic Signaling Pathway Positive Regulation Of Telomere Maintenance In Response To DNA Damage	Regulation Of Smooth Muscle Contraction Actin Filament Organization Actomyosin Structure Organization Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Pathways		UCH proteinases DNA Damage Recognition in GG-NER	Developmental Lineage of Mammary Gland Myoepithelial Cells
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Presence of antiphospholipid antibodies ( 27098658)
Interacting Genes		30 interacting genes: APP C19orf25 C4orf46 CCDC57 CCNDBP1 CDCA7L CNN1 DDIT4L DEUP1 DYDC1 EAF1 EAF2 ELL HAUS1 KRT19 LMO2 NOL3 PAWR PIM1 PIN1 PSMB1 RPGRIP1 RUNDC3A STK3 TCF3 TFIP11 TPM1 TPM2 TPM3 TRAF1	18 interacting genes: ACTA1 ADRB2 AKAP8 CALM1 CCHCR1 COG6 DNMBP ECSIT FYN MYO1A NCAPD2 PLRG1 PRKCE SYCE1 TFPT TPM3 TUBB UPF1
Entrez ID		29844	1264
HPRD ID		10266	02884
Ensembl ID		ENSG00000105619	ENSG00000130176
Uniprot IDs		P0C1Z6	B7Z7E1 P51911 Q53FP8 V9HWA5
PDB IDs			1WYP
Enriched GO Terms of Interacting Partners?		Muscle Thin Filament Tropomyosin Supramolecular Fiber Organization Transcription Elongation Factor Complex Actin Filament Super Elongation Complex Actin Filament Organization Structural Constituent Of Muscle Transcription Elongation By RNA Polymerase II Transcription Elongation Factor Activity Cytoskeleton Actin Cytoskeleton DNA-templated Transcription Elongation Regulation Of Extrinsic Apoptotic Signaling Pathway Cytoplasm Actin Binding Actin Filament Binding Microtubule Organizing Center Organization Regulation Of Transcription Elongation By RNA Polymerase II Apoptotic Process Protein Binding Cell Differentiation Involved In Embryonic Placenta Development Nuclear Speck Regulation Of DNA-templated Transcription Elongation Centriole Replication Programmed Cell Death Cell Death Actomyosin Structure Organization	Actin Filament Chromosome Organization Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Cell Body Mitotic Chromosome Condensation Cellular Response To Prostaglandin E Stimulus Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc Receptor Mediated Stimulatory Signaling Pathway Cellular Response To Prostaglandin Stimulus Regulation Of Metal Ion Transport Response To Prostaglandin E Mitotic Cell Cycle Protein-containing Complex Binding Regulation Of Calcium Ion Transmembrane Transport Cell Cycle Phase Transition Fc-gamma Receptor Signaling Pathway Condensed Chromosome Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Positive Regulation Of Mini Excitatory Postsynaptic Potential Regulation Of Monoatomic Ion Transport Innate Immune Response-activating Signaling Pathway Cellular Response To Glycine Response To Singlet Oxygen Toll-like Receptor 4 Signaling Pathway Cell Surface Toll-like Receptor Signaling Pathway Chromosome Condensation Cell Division Muscle Contraction Glutamate Receptor Signaling Pathway Cellular Response To Amyloid-beta Activation Of Innate Immune Response Cytoplasm Sarcomere Cellular Response To Oxygen-containing Compound Positive Regulation Of Organelle Organization Modulation Of Chemical Synaptic Transmission Cell Cycle G2/M Phase Transition Regulation Of Calcium Ion Transport Fc Receptor Signaling Pathway Cell Surface Pattern Recognition Receptor Signaling Pathway Chromosome Organization Involved In Meiotic Cell Cycle Response To Amyloid-beta Beta2-adrenergic Receptor Activity Negative Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Immune Response-activating Cell Surface Receptor Signaling Pathway Response To Glycine Ethanol Binding Regulation Of Chromosome Organization Muscle System Process
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