C6orf15 and YTHDF1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		C6orf15	YTHDF1
Description		chromosome 6 open reading frame 15	YTH N6-methyladenosine RNA binding protein F1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Matrix	P-body Cytoplasm Cytoplasmic Stress Granule
	Molecular Function	Protein Binding	RNA Binding MRNA Binding Protein Binding Ribosome Binding N6-methyladenosine-containing RNA Reader Activity
	Biological Process	Extracellular Matrix Organization	Immune System Process Regulation Of Antigen Processing And Presentation Learning Memory Stress Granule Assembly Regulation Of MRNA Stability Positive Regulation Of Translation Positive Regulation Of Translational Initiation MRNA Destabilization Organelle Assembly Regulation Of Long-term Synaptic Potentiation Regulation Of Axon Guidance
Pathways
Drugs
Diseases
GWAS		A body shape index ( 34021172) Apolipoprotein B levels ( 32203549) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Epstein-Barr virus immune response (EBNA-1) ( 23326239) Follicular lymphoma ( 20639881) Graves' disease ( 21841780) Hematology traits ( 23263863) Hip circumference adjusted for BMI ( 34021172) Hypothyroidism ( 22493691) Inflammatory bowel disease ( 28067908) Leprosy ( 32421744) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Malaria ( 31844061) Nickel levels ( 26025379) Response to hepatitis B vaccine ( 29534301) Rosacea symptom severity ( 29771307) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848) Small cell lung carcinoma ( 28604730) Thyrotoxic hypokalemic periodic paralysis and Graves disease ( 31050781) Type 1 diabetes (age at diagnosis) ( 33179336) Ulcerative colitis ( 28067908) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) White blood cell count ( 21738480)	Response to cytadine analogues (cytosine arabinoside) ( 24483146)
Interacting Genes		5 interacting genes: KRTAP6-2 PROP1 UBQLN2 VENTX YTHDF1	42 interacting genes: ABHD11 BATF2 BICD2 C6orf15 CFTR CLK2 CPSF7 CTTN DMRTB1 DYNC1I1 ERI3 FAM168A FHIT HEY1 HSF4 ITSN2 KRTAP13-1 KRTAP26-1 KRTAP7-1 KRTAP8-1 LASP1 MAGED1 MOV10 MSX2 OIP5 PPIL3 PRR32 PRRC2B QKI RBFOX2 RBM22 RBMS3 RBPMS SARNP SF1 SNCA SNRPA TLE5 TMED9 VPS37C XRN2 ZNF34
Entrez ID		29113	54915
HPRD ID		12856	11691
Ensembl ID		ENSG00000204542	ENSG00000149658
Uniprot IDs		M1T2K5 Q6UXA7	Q9BYJ9
PDB IDs			4RCI 4RCJ 7PCU 7QKN 7QL7 7YYE 7YYF 7YYJ 7YZ8 8BS4
Enriched GO Terms of Interacting Partners?			Nucleic Acid Binding MRNA Processing RNA Binding Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome MRNA Metabolic Process Negative Regulation Of Biosynthetic Process RNA Processing RNA Splicing, Via Transesterification Reactions RNA Splicing MRNA Binding
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