DCPS and CHST4

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		DCPS	CHST4
Description		decapping enzyme, scavenger	carbohydrate sulfotransferase 4
Image			No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol	Golgi Membrane Golgi Apparatus Trans-Golgi Network Membrane
	Molecular Function	RNA 7-methylguanosine Cap Binding RNA Exonuclease Activity Protein Binding Hydrolase Activity Identical Protein Binding 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] Diphosphatase Activity	N-acetylglucosamine 6-O-sulfotransferase Activity Sulfotransferase Activity Transferase Activity
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA MRNA Processing RNA Splicing MRNA Cis Splicing, Via Spliceosome MRNA Methylguanosine-cap Decapping	Carbohydrate Metabolic Process N-acetylglucosamine Metabolic Process Protein Sulfation Sulfur Compound Metabolic Process Inflammatory Response Immune Response Cell Adhesion Cell-cell Signaling Protein O-linked Glycosylation Via N-acetyl-galactosamine Positive Regulation Of Leukocyte Tethering Or Rolling
Pathways		mRNA decay by 3' to 5' exoribonuclease	O-linked glycosylation of mucins
Drugs		7-methyl-GpppA 7-methyl-7,8-dihydroguanosine-5'-diphosphate 7-methyl-5'-guanylic acid 7-methyl-guanosine-5'-triphosphate-5'-guanosine 5-{[1-(2-fluorobenzyl)piperidin-4-yl]methoxy}quinazoline-2,4-diamine 5-{[1-(2,3-dichlorobenzyl)piperidin-4-yl]methoxy}quinazoline-2,4-diamine 5-[(1S)-1-(3-chlorophenyl)ethoxy]quinazoline-2,4-diamine
Diseases
GWAS		Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494) Lymphocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 27863252 32888494)
Interacting Genes		11 interacting genes: CDC20 CDC27 CEBPA CHST4 CSNK2A2 FZR1 GPC5 KPNA2 KPNA5 KPNA6 YWHAQ	2 interacting genes: CD34 DCPS
Entrez ID		28960	10164
HPRD ID		16787	07477
Ensembl ID		ENSG00000110063	ENSG00000140835
Uniprot IDs		A0A384MTI8 Q96C86	Q8NCG5
PDB IDs		1ST0 1ST4 1XML 1XMM 3BL7 3BL9 3BLA 4QDE 4QDV 4QEB 5OSY
Enriched GO Terms of Interacting Partners?		NLS-dependent Protein Nuclear Import Complex Anaphase-promoting Complex-dependent Catabolic Process Anaphase-promoting Complex NLS-bearing Protein Import Into Nucleus Nuclear Localization Sequence Binding Nuclear Import Signal Receptor Activity Entry Of Viral Genome Into Host Nucleus Through Nuclear Pore Complex Via Importin Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Viral Penetration Into Host Nucleus Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Positive Regulation Of Ubiquitin Protein Ligase Activity Regulation Of Meiotic Cell Cycle Metaphase/anaphase Transition Of Cell Cycle Intracellular Transport Of Virus Anaphase-promoting Complex Binding Ubiquitin-protein Transferase Activator Activity Host Cell Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Ubiquitin Ligase Activator Activity Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Protein Import Into Nucleus Import Into Nucleus Regulation Of Protein Catabolic Process Regulation Of Chromosome Segregation Histone Deacetylase Binding Regulation Of Proteolysis Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Viral Life Cycle Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Meiotic Nuclear Division Protein Localization To Nucleus Regulation Of Reproductive Process Positive Regulation Of Proteolysis Positive Regulation Of Protein Catabolic Process Protein K11-linked Ubiquitination Regulation Of Cell Cycle Nuclear Transport Nucleocytoplasmic Transport Animal Organ Regeneration Metaphase/anaphase Transition Of Meiosis I RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Nucleoplasm Positive Regulation Of Viral Process Regulation Of Cell Cycle Process Regulation Of Chromosome Separation	Extracellular Exosome Assembly Metanephric Glomerular Mesangial Cell Differentiation Glomerular Endothelium Fenestra Mesangial Cell-matrix Adhesion 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] Diphosphatase Activity Positive Regulation Of Granulocyte Colony-stimulating Factor Production Positive Regulation Of Macrophage Colony-stimulating Factor Production Transdifferentiation Sulfate Binding Pericyte Cell Differentiation Paracrine Signaling Glomerular Epithelium Development Glomerular Endothelium Development Positive Regulation Of Odontogenesis Regulation Of Macrophage Colony-stimulating Factor Production Vascular Wound Healing Glomerular Filtration Regulation Of Vasculogenesis Regulation Of Odontogenesis Endothelium Development Angiogenesis Involved In Wound Healing Positive Regulation Of Vasculogenesis Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay RNA 7-methylguanosine Cap Binding Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA MRNA Methylguanosine-cap Decapping RNA Exonuclease Activity MRNA Cis Splicing, Via Spliceosome Renal Filtration RNA Decapping Hematopoietic Stem Cell Proliferation Negative Regulation Of Interleukin-2 Production Cell Differentiation Involved In Kidney Development Endothelial Cell Proliferation Negative Regulation Of Gene Expression Regulation Of Interleukin-2 Production Basal Plasma Membrane Kidney Epithelium Development Stem Cell Proliferation Regulation Of Animal Organ Morphogenesis Cell Periphery Intercellular Bridge MRNA Destabilization P-body RNA Destabilization Cell-matrix Adhesion Nuclear-transcribed MRNA Catabolic Process Positive Regulation Of MRNA Catabolic Process Renal System Process MRNA Catabolic Process
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