FFAR2 and YIPF6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FFAR2	YIPF6
Description		free fatty acid receptor 2	Yip1 domain family member 6
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Cell Projection	Golgi Trans Cisterna Golgi Membrane Endoplasmic Reticulum Golgi Apparatus Golgi Medial Cisterna Cis-Golgi Network Trans-Golgi Network Endomembrane System Membrane COPII-coated ER To Golgi Transport Vesicle
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Lipid Binding	Protein Binding Identical Protein Binding
	Biological Process	Leukocyte Chemotaxis Involved In Inflammatory Response Immune System Process Mucosal Immune Response Regulation Of Acute Inflammatory Response Positive Regulation Of Cytokine Production Involved In Immune Response Cell Surface Pattern Recognition Receptor Signaling Pathway Positive Regulation Of Acute Inflammatory Response To Non-antigenic Stimulus Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Lipid Storage Positive Regulation Of Insulin Secretion Positive Regulation Of Chemokine Production Positive Regulation Of Interleukin-8 Production Glucose Homeostasis Fat Cell Differentiation Negative Regulation Of Insulin Secretion Cellular Response To Fatty Acid Regulation Of Peptide Hormone Secretion Ligand-gated Ion Channel Signaling Pathway	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intestinal Epithelial Cell Development
Pathways		G alpha (q) signalling events Free fatty acid receptors	Golgi Associated Vesicle Biogenesis
Drugs		GLPG-0974
Diseases
GWAS		Hemoglobin ( 32888494) Iron status biomarkers (iron levels) ( 33536631) Iron status biomarkers (transferrin saturation) ( 33536631) Metabolite levels ( 23823483) Monocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494)	Male-pattern baldness ( 28196072)
Interacting Genes		120 interacting genes: AGPAT4 AGTRAP ALOX5AP ANKRD46 APOD ARLN ATP13A1 ATP6V0C BMP10 BNIP3 BTN2A2 C11orf24 C3orf52 CACNG1 CATSPERH CBLIF CCDC167 CD82 CDIPT CFHR5 CGRRF1 CLDN4 CLDND2 CLEC1A CMTM5 CMTM7 CNIH1 COL4A5 CXCL16 CXCL9 CYB561A3 CYB5R2 DERL1 EDDM3B EMC6 EMP1 ERG28 FAM20B FAM3C FAXDC2 FCER1G FIS1 FXYD3 FXYD6 FZD7 GALNT15 GJB2 GNAO1 GNAQ GPR37L1 GUCA2A GYPA IFITM3 IGF1R IGFBP5 KRT1 KTN1 LAPTM4A LAT LEPROTL1 LHFPL5 LPAR3 MALL MS4A13 NAT8 NIPAL4 NKG7 NRM NSG1 NUCB2 OR10AG1 PEX16 PLP1 PMP22 PNLIPRP1 RPRM RTP2 RUSF1 SACM1L SCGB1D1 SELENOK SERP2 SLC30A2 SLC35B4 SLC35E3 SLC35H1 SLC38A1 SLC38A7 SLC39A9 SLC41A1 SLC61A1 SMAGP SMCO4 SMIM1 STRIT1 STX8 SYNDIG1 TEX264 TM4SF4 TMEM11 TMEM120B TMEM128 TMEM144 TMEM147 TMEM203 TMEM218 TMEM229B TMEM239 TMEM243 TMEM60 TMEM86A TMEM86B TMEM97 TNF TSPO2 UNC50 UPK1B YIF1A YIPF2 YIPF6	93 interacting genes: APOL2 AQP2 AQP6 ARL13B ATP6V0E1 CD79A CGRRF1 CISD2 CLN8 CNR2 CPLX4 CRB3 CREB3L1 CREB3L3 CXorf66 CYSLTR2 EBP EFNA5 ELOVL4 ERGIC3 F2RL1 FAM209A FCER1G FFAR2 FKBP7 GJA5 GJA8 GJB1 GPR101 GPR152 GPR42 GPX8 HSD17B11 IL10RA IL1RL1 IL27RA JKAMP KCNJ6 KCNK5 LMNA LRRC25 LRRC3B LRRC4C LY6G6C LYVE1 MMD MS4A3 MTIF3 MUC1 NDUFAF1 ODF4 PDZK1IP1 PSCA RAET1L REEP4 RETREG3 RHCG RNF185 SCN3B SLC10A1 SLC10A6 SLC12A7 SLC17A8 SLC18A1 SLC30A4 SLC30A8 SLC35H1 SLC38A7 SLC39A1 SLC39A2 SLC61A1 SLC71A2 SLC7A14 SLC7A8 SSMEM1 STOM TCTA THAP4 TMEM106C TMEM11 TMEM130 TMEM14B TMEM237 TMEM31 TMEM52B TMEM71 TMX2 TRARG1 TRHR TVP23B ULBP2 YIPF1 YIPF2
Entrez ID		2867	286451
HPRD ID		04824	06639
Ensembl ID		ENSG00000126262	ENSG00000181704
Uniprot IDs		C6KYL4 O15552	Q96EC8
PDB IDs		8J22 8J23 8J24 8T3S 9K1D
Enriched GO Terms of Interacting Partners?		Membrane Protein Binding Endoplasmic Reticulum Membrane Endoplasmic Reticulum Plasma Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Bleb Assembly Alkenylglycerophosphocholine Hydrolase Activity Transmembrane Transport	Membrane Transmembrane Transport Plasma Membrane Protein Binding Endoplasmic Reticulum Monoatomic Ion Transport Zinc Ion Transmembrane Transporter Activity Monoatomic Cation Transport Zinc Ion Transmembrane Transport Zinc Ion Transport Metal Ion Transport Inorganic Cation Transmembrane Transport Endoplasmic Reticulum Membrane Inorganic Ion Transmembrane Transport Regulation Of Renin Secretion Into Blood Stream Amino Acid Transmembrane Transport Connexin Complex Import Across Plasma Membrane Gap Junction Channel Activity Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Bile Acid:sodium Symporter Activity Positive Regulation Of Acute Inflammatory Response Gap Junction Transmembrane Transporter Activity SA Node Cell Action Potential Side Of Membrane Amino Acid Transport Carboxylic Acid Transport Organic Acid Transport Organic Anion Transport Regulation Of Ventricular Cardiac Muscle Cell Membrane Depolarization Monoatomic Cation Transmembrane Transport Neurotransmitter Loading Into Synaptic Vesicle Renal Water Transport Monoatomic Ion Transmembrane Transport Gap Junction Assembly Golgi Trans Cisterna Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Ammonium Channel Activity G Protein-coupled Receptor Activity Regulation Of Atrial Cardiac Muscle Cell Membrane Depolarization Golgi Medial Cisterna
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