FFAR3 and TOMM6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FFAR3	TOMM6
Description		free fatty acid receptor 3	translocase of outer mitochondrial membrane 6
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GO Annotations	Cellular Component	Plasma Membrane Membrane	Mitochondrion Mitochondrial Outer Membrane Mitochondrial Outer Membrane Translocase Complex Membrane TOM Complex
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Lipid Binding	Protein Binding
	Biological Process	Immune System Process Mucosal Immune Response Positive Regulation Of Cytokine Production Involved In Immune Response Positive Regulation Of Acute Inflammatory Response To Non-antigenic Stimulus Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Regulation Of Norepinephrine Secretion Positive Regulation Of Chemokine Production Negative Regulation Of Blood Pressure Regulation Of Insulin Receptor Signaling Pathway Regulation Of Hormone Biosynthetic Process Cellular Response To Fatty Acid Regulation Of Peptide Hormone Secretion	Protein Transport Protein Insertion Into Mitochondrial Outer Membrane
Pathways		G alpha (q) signalling events Free fatty acid receptors	Mitochondrial protein import PINK1-PRKN Mediated Mitophagy
Drugs
Diseases
GWAS			Hip circumference adjusted for BMI ( 34021172)
Interacting Genes		13 interacting genes: CD79A COMT CTXN3 EFNA5 LAT LTC4S SERINC1 SLC41A1 TEX264 TOMM6 TREX1 UNC93B1 YIPF1	15 interacting genes: AQP6 C1orf159 CD68 CERS4 DNAH8 ERGIC3 FFAR3 GLP1R HUNK ODF4 SEC61A2 SLC10A1 SLC16A2 SLC18A2 TMEM14B
Entrez ID		2865	100188893
HPRD ID		04823	19464
Ensembl ID		ENSG00000185897	ENSG00000214736
Uniprot IDs		A0A0K0PUW7 O14843	Q96B49
PDB IDs		8J20 8J21	7CK6 7CP9 7VBY 7VC4 7VD2 7VDD 8XVA 9EIH 9EII 9EIJ
Enriched GO Terms of Interacting Partners?		T Cell Antigen Processing And Presentation Membrane Adaptive Immune Response Immune Response-activating Signaling Pathway Immune Response-regulating Signaling Pathway Activation Of Immune Response Norepinephrine Secretion Catechol O-methyltransferase Activity Neurotrophin TRKC Receptor Binding Neurotrophin TRKB Receptor Binding Endoplasmic Reticulum Membrane Immune Complex Formation Adenyl Deoxyribonucleotide Binding Immune Response In Brain Or Nervous System	Post-translational Protein Targeting To Membrane, Translocation Hormone Secretion Hormone Transport Transmembrane Transport Membrane Intracellular Protein Transmembrane Transport Signal Release Nitrate Transmembrane Transporter Activity Glucagon-like Peptide 1 Receptor Activity Negative Regulation Of Blood Pressure Serotonin Secretion By Mast Cell Somato-dendritic Dopamine Secretion Regulation Of Hormone Levels PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Positive Regulation Of Acute Inflammatory Response To Non-antigenic Stimulus Thyroid-stimulating Hormone Secretion Aminergic Neurotransmitter Loading Into Synaptic Vesicle Retrograde Transporter Complex, Golgi To ER Protein Transmembrane Transport Glucagon Receptor Activity Histamine Uptake Serotonin:sodium:chloride Symporter Activity
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